2023
Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers
Hennein R, Lowe S, Feingold J, Feder A, Peccoralo L, Ripp J, Mazure C, Pietrzak R. Pre- and peri-traumatic event stressors drive gender differences in chronic stress-related psychological sequelae: A prospective cohort study of COVID-19 frontline healthcare providers. Journal Of Psychiatric Research 2023, 162: 88-94. PMID: 37105023, DOI: 10.1016/j.jpsychires.2023.04.009.Peer-Reviewed Original ResearchConceptsMajor depressive disorderPosttraumatic stress disorderProspective cohort studyHealthcare providersCohort studyLarge tertiary care hospitalPsychological sequelaeSymptoms of MDDMental health risk factorsTertiary care hospitalProbable major depressive disorderWomen's healthcare providersHealth risk factorsFrontline healthcare providersCare hospitalRisk factorsDepressive disorderGender differencesStress disorderAnxiety disordersWomenSequelaeCOVID-19DisordersCOVID-19 pandemic
2021
Research on Posttraumatic Stress Disorder in the Context of the COVID-19 Pandemic: A Review of Methods and Implications in General Population Samples
Husky M, Pietrzak R, Marx B, Mazure C. Research on Posttraumatic Stress Disorder in the Context of the COVID-19 Pandemic: A Review of Methods and Implications in General Population Samples. Chronic Stress 2021, 5: 24705470211051327. PMID: 34765850, PMCID: PMC8576091, DOI: 10.1177/24705470211051327.Peer-Reviewed Original ResearchPosttraumatic stress disorderStress disorderGeneral population sampleMental disordersCOVID-19 pandemicPre-existing mental disordersSevere posttraumatic symptomsPopulation samplePublic health planningDirect trauma exposurePosttraumatic stress disorder (PTSD) symptomsCross-sectional designGeneral populationSnowball sampling strategiesHealth planningTrauma exposureMental healthStatistical ManualDisordersDisorder symptomsInadequate assessmentCriterion ASymptomsPosttraumatic symptomsSelf-report measures
2016
Brain circuitry associated with the development of substance use in bipolar disorder and preliminary evidence for sexual dimorphism in adolescents
Lippard ET, Mazure CM, Johnston JA, Spencer L, Weathers J, Pittman B, Wang F, Blumberg HP. Brain circuitry associated with the development of substance use in bipolar disorder and preliminary evidence for sexual dimorphism in adolescents. Journal Of Neuroscience Research 2016, 95: 777-791. PMID: 27870392, PMCID: PMC5123602, DOI: 10.1002/jnr.23901.Peer-Reviewed Original ResearchConceptsGray matter volumePrefrontal gray matter volumeBipolar disorderSubstance use problemsFuture substance useSubstance useLower gray matter volumeUse problemsFuture substance use problemsRegional gray matter volumeStructural magnetic resonanceAdverse outcomesTemporopolar cortexInsula gray matter volumeSubstance exposureMood disordersHigh riskLower riskSubsequent alcoholMatter volumeNeurodevelopmental basisSubstance problemsDisordersAdolescentsMales
2010
Computerized ambulatory monitoring in mood disorders: Feasibility, compliance, and reactivity
Husky MM, Gindre C, Mazure CM, Brebant C, Nolen-Hoeksema S, Sanacora G, Swendsen J. Computerized ambulatory monitoring in mood disorders: Feasibility, compliance, and reactivity. Psychiatry Research 2010, 178: 440-442. PMID: 20488558, DOI: 10.1016/j.psychres.2010.04.045.Peer-Reviewed Original Research
2009
Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal
Weinberger AH, Maciejewski PK, McKee SA, Reutenauer EL, Mazure CM. Gender Differences in Associations between Lifetime Alcohol, Depression, Panic Disorder, and Posttraumatic Stress Disorder and Tobacco Withdrawal. American Journal On Addictions 2009, 18: 140-147. PMID: 19283566, PMCID: PMC2874459, DOI: 10.1080/10550490802544888.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceAbuse/dependenceMajor depressionWithdrawal symptomsPsychiatric statusSmoking relapsePanic disorderIndices of withdrawalStrong associationSmoking cessation interventionNational Comorbidity SurveyPosttraumatic stress disorderGender-specific effectsCessation interventionsNicotine withdrawalTobacco withdrawalRetrospective dataStress disorderLifetime alcoholLonger durationDepressionWithdrawalDisordersRelapseMultiple regression analysis
2002
Gambling
Potenza MN, Fiellin DA, Heninger GR, Rounsaville BJ, Mazure CM. Gambling. Journal Of General Internal Medicine 2002, 17: 721-732. PMID: 12220370, PMCID: PMC1495100, DOI: 10.1046/j.1525-1497.2002.10812.x.Peer-Reviewed Educational Materials
1999
Selective Speech Perception Alterations in Schizophrenic Patients Reporting Hallucinated Voices
Hoffman RE, Rapaport J, Mazure CM, Quinlan DM. Selective Speech Perception Alterations in Schizophrenic Patients Reporting Hallucinated Voices. American Journal Of Psychiatry 1999, 156: 393-399. PMID: 10080554, DOI: 10.1176/ajp.156.3.393.Peer-Reviewed Original ResearchConceptsSpeech perceptionSchizophrenia spectrum disordersMasked speechSpectrum disorderAuditory continuous performance taskNeural network computer simulationSentence repetition performanceContinuous performance taskSentence repetition taskNonhallucinating patientsRepetition taskAttentional deficitsAttention impairmentRepetition performancePerformance taskPerception alterationHallucinated voicesMemory systemTaskPerceptionSpeechSchizophrenic patientsNonlanguageDisordersMemory
1998
Management of the Adverse Effects of Clozapine
Young CR, Bowers MB, Mazure CM. Management of the Adverse Effects of Clozapine. Schizophrenia Bulletin 1998, 24: 381-390. PMID: 9718630, DOI: 10.1093/oxfordjournals.schbul.a033333.Peer-Reviewed Original ResearchConceptsAdverse effectsElevated liver enzymesPercent of patientsSuccessful pharmacological managementPositive therapeutic outcomesHypothesized pathophysiologyPharmacological managementRefractory schizophreniaNeuromuscular effectsTraditional neurolepticsLiver enzymesPharmacological interventionsClozapineAffective disordersTherapeutic outcomesNeurological disordersMental disordersMaximum doseObsessive-compulsive symptomsWeight gainDisordersPatientsPathophysiologyNew hopeTreatmentMeasurement of dissociative states with the Clinician‐Administered Dissociative States Scale (CADSS)
Bremner J, Krystal J, Putnam F, Southwick S, Marmar C, Charney D, Mazure C. Measurement of dissociative states with the Clinician‐Administered Dissociative States Scale (CADSS). Journal Of Traumatic Stress 1998, 11: 125-136. PMID: 9479681, DOI: 10.1023/a:1024465317902.Peer-Reviewed Original Research
1997
The Expanding Indications for Clozapine
Young C, Longhurst J, Bowers M, Mazure C. The Expanding Indications for Clozapine. Experimental And Clinical Psychopharmacology 1997, 5: 216-234. PMID: 9260069, DOI: 10.1037/1064-1297.5.3.216.Peer-Reviewed Original ResearchConceptsUnique pharmacodynamic profileUse of clozapineTreatment-resistant schizophreniaTraditional drug treatmentExpanding IndicationsClozapine treatmentNeurologic conditionsPharmacodynamic profileClinical indicationsDrug treatmentMood disordersEffective treatmentClozapineSubstance abuseChildhood schizophreniaRelevant literatureSchizophreniaDisordersTreatmentAggressive behaviorIndicationsInitial rationaleAgranulocytosisPatientsBody of literatureChronic neuroleptic exposure in bipolar outpatients.
Sernyak MJ, Godleski LS, Griffin RA, Mazure CM, Woods SW. Chronic neuroleptic exposure in bipolar outpatients. The Journal Of Clinical Psychiatry 1997, 58: 193-5. PMID: 9184612, DOI: 10.4088/jcp.v58n0503.Peer-Reviewed Original ResearchConceptsChronic neuroleptic exposureNeuroleptic exposureBipolar outpatientsBipolar disorderConnecticut Mental Health CenterChronic neuroleptic administrationMental health centersComputerized administrative databasesNeuroleptic medicationChlorpromazine equivalentsNeuroleptic administrationChronic useMedical recordsAdministrative databasesNeuroleptic dosageHealth centersBipolar patientsPatientsOutpatientsReview criteriaDisordersExposurePast yearMedicationsDiagnosis
1996
Possible acceleration of alcoholic cirrhosis in a patient with bulimia
Platis I, Carpenter L, Vojvoda D, Bowers M, Mazure C. Possible acceleration of alcoholic cirrhosis in a patient with bulimia. International Journal Of Eating Disorders 1996, 20: 439-442. PMID: 8953333, DOI: 10.1002/(sici)1098-108x(199612)20:4<439::aid-eat13>3.0.co;2-t.Peer-Reviewed Original Research
1989
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale: II. Validity. JAMA Psychiatry 1989, 46: 1012-1016. PMID: 2510699, DOI: 10.1001/archpsyc.1989.01810110054008.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleYale-Brown scaleScale scoreCompulsive ScaleSecondary depressive symptomsPlacebo-controlled trialCohort of patientsDrug-induced changesObsessive-compulsive disorder symptom severityMeasures of depressionDrug trialsOutcome measuresDisorder symptom severityDepressive symptomsObsessive-compulsive disorder symptomsSymptom severityPatientsBaseline ratingsDisordersDisorder symptomsValid instrumentSymptomsTrials