Chee San Tong
Associate Research Scientist in Cell BiologyCards
About
Research
Publications
2025
Pangenome analysis of Liriodendron reveals presence/absence variations associated with growth traits
Wu H, Chen S, Wang J, Zong Y, Yang L, Tong C, Li H. Pangenome analysis of Liriodendron reveals presence/absence variations associated with growth traits. BMC Plant Biology 2025, 25: 1039. PMID: 40781705, PMCID: PMC12333063, DOI: 10.1186/s12870-025-07109-1.Peer-Reviewed Original ResearchConceptsGene presence/absence variationGenome-wide association studiesPresence/absence variationSpecies genetic diversitySingle nucleotide polymorphismsGrowth traitsNon-reference sequencesMolecular marker-assisted breedingMarker-assisted breedingDominant expression patternHeterotic combinationsCombination of leafReference genomeResequencing dataPangenome analysisGenetic diversityNovel genesAssociation studiesGenomic datasetsPhloem tissueCandidate genesCore genesGenetic basisNucleotide polymorphismsLiriodendron
2024
Competition and synergy of Arp2/3 and formins in nucleating actin waves
Le Chua X, San Tong C, Su M, Xǔ X, Xiao S, Wu X, Wu M. Competition and synergy of Arp2/3 and formins in nucleating actin waves. Cell Reports 2024, 43: 114423. PMID: 38968072, PMCID: PMC11378572, DOI: 10.1016/j.celrep.2024.114423.Peer-Reviewed Original ResearchActin wavesActin regulatory proteinsActin cytoskeletal networkConstitutively active mutantArp2/3 complexActin assemblyMonomeric actinActive Cdc42Cdc42-interactingCytoskeletal networkArp2/3Active mutantCellular processesRegulatory proteinsUpstream regulatorCdc42ActinPlasma membraneFMNL1Complex feedback loopsForminPhysiological stateDelayed recruitmentFeedback loopGTPaseLeaf morphology related genes revealed by integrating Pan‐transcriptome, GWAS and eQTL analyses in a Liriodendron population
Wu H, Liu X, Zong Y, Yang L, Wang J, Tong C, Li H. Leaf morphology related genes revealed by integrating Pan‐transcriptome, GWAS and eQTL analyses in a Liriodendron population. Physiologia Plantarum 2024, 176: e14392. PMID: 38887911, DOI: 10.1111/ppl.14392.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociGenome-wide association studiesTranscriptome-wide association studyComplex genetic basisMolecular regulatory mechanismsPan-transcriptomeLeaf morphogenesisLeaf morphologyAssociation studiesMolecular breedingMorphological traitsLeaf shapeGenome-wide association study analysisLeaf sizeExpression quantitative trait loci analysisExpression of downstream genesGlobal expression differencesLeaf morphological traitsQuantitative trait lociCo-expression analysisLeaf morphological developmentCis-eQTLsLinkage mapAllelic lociTrait loci
2023
Periodicity, mixed-mode oscillations, and multiple timescales in a phosphoinositide-Rho GTPase network
San Tong C, Xǔ X, Wu M. Periodicity, mixed-mode oscillations, and multiple timescales in a phosphoinositide-Rho GTPase network. Cell Reports 2023, 42: 112857. PMID: 37494180, DOI: 10.1016/j.celrep.2023.112857.Peer-Reviewed Original ResearchRe-annotation of the Liriodendron chinense genome identifies novel genes and improves genome annotation quality
Wu H, Hao Z, Tu Z, Zong Y, Yang L, Tong C, Li H. Re-annotation of the Liriodendron chinense genome identifies novel genes and improves genome annotation quality. Tree Genetics & Genomes 2023, 19: 30. DOI: 10.1007/s11295-023-01605-x.Peer-Reviewed Original ResearchL. chinense genomePacBio long readsL. chinenseLong readsNovel genesAlternative splicingTranscriptome dataTranscriptome analysisAb initio annotationIllumina short readsWhole-genome scaleLeaf shape developmentAnatomical structure formationGenetic linkage mapGene function discoveryPlant organ formationFunction of genesGene function studiesComplete BUSCOsNuclear genomeShort readsLinkage mapGenomic analysisGene modelsFunction discovery
2018
Membrane shape-mediated wave propagation of cortical protein dynamics
Wu Z, Su M, Tong C, Wu M, Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nature Communications 2018, 9: 136. PMID: 29321558, PMCID: PMC5762918, DOI: 10.1038/s41467-017-02469-1.Peer-Reviewed Original ResearchConceptsMembrane shape changesF-BAR proteinsDomain-containing proteinsPeripheral membrane proteinsProtein lateral diffusionActin machineryProtein recruitmentMembrane proteinsProtein dynamicsCortical proteinsShape changesProtein waveActin wavesUnderappreciated roleProteinMembrane undulationsLateral diffusionSpatial gradientsMachineryCytoplasmImmune cellsRecruitmentAssemblyCells
2017
Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information
Xiao S, Tong C, Yang Y, Wu M. Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information. Developmental Cell 2017, 43: 493-506.e3. PMID: 29161593, DOI: 10.1016/j.devcel.2017.10.023.Peer-Reviewed Original Research
2011
Haplotype Analysis of Complex Traits in Outcrossing Tree Species: Allele Discovery of Quantitative Trait Loci
Liu T, Tong C, Luo J, Wu J, Zhang B, Cui Y, Li Y, Zeng Y, Wu R. Haplotype Analysis of Complex Traits in Outcrossing Tree Species: Allele Discovery of Quantitative Trait Loci. 2011, 62-84. DOI: 10.1201/b10819-3.Peer-Reviewed Original ResearchQuantitative trait lociAllele discoveryGenetic mapOutcrossing speciesComplex traitsTrait lociQuantitative traitsComplex network of genetic regulationHaplotype analysisAvailability of polymorphic markersGenetic mapping of quantitative trait lociDiscovery of quantitative trait lociMapping of quantitative trait lociAnalysis of complex traitsQuantitative trait locus mappingOutcrossing tree speciesQuantitative trait locus allelesHigh-resolution mappingMapping of genesComplex quantitative traitsMarker-assisted selectionFull-sib familiesHaplotype approachLinkage phasePolymorphic markers