Osteoporosis is a silent and debilitating disease that leads to fractures and pain. Most fractures target the femoral head, the wrist and the spine. A recent research focus in our lab has been the development of a novel approach to target the formation of new bone to specific skeletal sites. This new technology combines stem cells, nano-material and PTH. We are in the process of translating the data generated in rats into larger animals, such as rabbits, and eventually in humans. We are most interested in studying the molecular mechanisms that mediate the formation of that new bone.