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Nikhil Victor Sikand, MD, FACC

Assistant Professor of Medicine (Cardiovascular Medicine)
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Additional Titles

Medical Director, Heart Transplant and Durable Mechanical Circulatory Support Programs, Cardiovascular Medicine

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Training

Advanced Heart Failure and Transplant Cardiology Fellow
New York University School of Medicine (2022)


Cardiovascular Disease Fellow
New York University School of Medicine (2019)


Resident
Yale University Traditional Medicine Residency Program (2016)


About

Titles

Assistant Professor of Medicine (Cardiovascular Medicine)

Medical Director, Heart Transplant and Durable Mechanical Circulatory Support Programs, Cardiovascular Medicine

Appointments

Other Departments & Organizations

Education & Training

Advanced Heart Failure and Transplant Cardiology Fellow
New York University School of Medicine (2022)
Cardiovascular Disease Fellow
New York University School of Medicine (2019)
Resident
Yale University Traditional Medicine Residency Program (2016)
Intern
Yale University Traditional Medicine Residency Program (2014)
MD
Tufts University School of Medicine (2013)
BA
Trinity College

Research

Overview

Medical Research Interests

Cardiomyopathies; Critical Care; Education, Medical; Heart Failure; Heart Transplantation

Research at a Glance

Yale Co-Authors

Frequent collaborators of Nikhil Victor Sikand's published research.

Publications

Featured Publications

  • Aficamten for Symptomatic Nonobstructive Hypertrophic Cardiomyopathy
    Masri A, Maron MS, Bhatia A, Peña-Peña ML, Sherrid MV, Figueiredo EL, Arad M, Barriales-Villa R, Choudhury L, Claggett BL, Coats CJ, Correia EDB, Costabel JP, Elliott PM, Silva Enciso JE, Garcia-Pavia P, Ge J, Hegde SM, Lewis GD, Lopes RD, Martinez MW, Maurer MS, Miao ZM, Michels M, Mitter SS, Pino Moreno JE, Olivotto I, Owens AT, Poulsen SH, Rader F, Rowin EJ, Schulze PC, Sepp R, Sikand N, Solomon SD, Spertus JA, Teale C, Zhao X, Divanji PH, Heitner SB, Jacoby DL, Kupfer S, Malik FI, Salazar-Mendiguchía J, Wohltman A, Zhuo S, Ho CY. Aficamten for Symptomatic Nonobstructive Hypertrophic Cardiomyopathy. New England Journal Of Medicine 2026, NEJMoa2603021. DOI: 10.1056/NEJMoa2603021.
    Peer-Reviewed Original Research
  • Effect of Aficamten on Cardiac Structure and Function in Patients with Symptomatic Nonobstructive Hypertrophic Cardiomyopathy
    Hegde SM, Wang X, Bhatia A, Peña-Peña ML, Sherrid MV, Figueiredo EL, Arad M, Barriales-Villa R, Choudhury L, Claggett BL, Coats CJ, de Barros Correia E, Costabel JP, Elliott PM, Silva Enciso JE, Garcia-Pavia P, Ge J, Ho CY, Lakdawala NK, Lewis GD, Maron MS, Martinez MW, Masri A, Maurer MS, Michels M, Mitter SS, Pino Moreno JE, Nagy V, Olivotto I, Owens AT, Poulsen SH, Rader F, Rowin EJ, Ruda M, Schulze PC, Sikand N, Spertus JA, Zhao X, Divanji PH, Heitner SB, Jacoby DL, Kupfer S, Malik FI, Salazar-Mendiguchía J, Wohltman A, Zhuo S, Solomon SD, Salomone O, Selvanayagam J, McKenzie S, Patel V, Antunes M, Jose Alvarez Ramires F, Vellosa Schwartzmann P, Francisco Kerr Saraiva J, Pimentel Filho P, Fontales Ritt LE, Simões MV, de Lima CEB, Vieira Moreira MDC, Tadros R, Zieroth S, Caddell A, Tyrrell B, Costa-Vitali A, Jin W, Hou A, Zhang Y, Yuan Z, Li L, Li Y, Li X, Zheng Y, Dong Y, Ma W, Thune JJ, Hey TM, Ricci JE, Habib G, Logeart D, Piriou N, Hagège A, Lairez O, Roubille F, Réant P, Brandenburg S, Meder B, Edelmann F, Vlachopoulos C, Anastasakis A, Prappa GFE, Efthimiadis G, Sepp R, Merkely B, Adalsteinsdottir B, Halabi M, Zwas D, Assali A, Piltz X, Piepoli M, Ammirati E, Todiere G, Angela Losi M, Sinagra G, Metra M, Volterrani M, Brunetti N, Crotti L, Amin A, Knackstedt C, Wojakowski W, Krakowiak B, Guerreiro R, Toste Batista A, Mesquita Bastos JA, Aguiar Rosa S, Azevedo O, Rincón Diaz LM, Hidalgo-Urbano RJ, Álvarez AG, Ferrer MDA, Pinilla JMG, Espinosa Castro MA, Restrepo Córdoba MA, Blanes JRG, Quesada R, Ripoll Vera TV, Choy AM, Cooper R, Raman B, Pantazis A, Tome Esteban MT, MacNamara J, Nassif ME, Arora P, Tower-Rader A, Afshar K, Saberi S, Nagueh S, Phelan D, Hazday M, Wang J, Wharton R, Hannawi B, Bering P, Moss N, Bilen O, Ravi S, Flanagan M, Galazka P, Wong T, Desai M, Geske J, Halbmaier K, Stehlik J, Brinkley M, Zenker M, Atkins J, Harper M, Collado E, Markowitz J, Naidu S, Darlington A, Xie L, Weiner S, Ravichandran A, Doll J, Bianco C, McDonald D, Lander B, Roldan P, Abraham T, Kelly J, Jani S, Amin AH, Malhotra S, French W, Murray D, Mudd J. Effect of Aficamten on Cardiac Structure and Function in Patients with Symptomatic Nonobstructive Hypertrophic Cardiomyopathy. Circulation 2026, CIRCULATIONAHA.126.082343. DOI: 10.1161/CIRCULATIONAHA.126.082343.
    Peer-Reviewed Original Research
  • Global Efficacy of Aficamten in Nonobstructive Hypertrophic Cardiomyopathy: Results From ACACIA-HCM
    Maron MS, Masri A, Bhatia A, Peña-Peña ML, Sherrid MV, Figueiredo EL, Arad M, Choudhury L, Claggett BL, Coats CJ, de Barros Correia E, Costabel JP, Elliott PM, Silva Enciso JE, Ge J, Ho CY, Kulac I, Lewis GD, Martinez MW, Maurer MS, Michels M, Mitter SS, Pino Moreno JE, Olivotto I, Owens AT, Poulsen SH, Rader F, Rowin EJ, Schulze PC, Sepp R, Sikand N, Solomon SD, Spertus JA, Zhao X, Divanji PH, Heitner SB, Jacoby DL, Kupfer S, Malik FI, Salazar-Mendiguchía J, Wohltman A, Zhuo S, Barriales-Villa R, Costabel JP, Salomone O, Selvanayagam J, McKenzie S, Patel V, Figueiredo E, Antunes M, Barros Correia E, Alvarez Ramires FJ, Vellosa Schwartzmann P, Kerr Saraiva JF, Pimentel Filho P, Eduardo Ritt L, Vinicius Simões M, Batista de Lima CE, da Consolação Moreira M, Tadros R, Zieroth S, Caddell A, Tyrrell B, Costa Vitali A, Zhao X, Jin W, Ge J, Hou A, Zhang Y, Yuan Z, Li L, Li Y, Li X, Zheng Y, Dong Y, Ma W, H. Poulsen S, Jakob Thune J, Morris Hey T, Ricci JE, Habib G, Logeart D, Piriou N, Hagege A, Lairez O, Roubille F, Reant P, Schulze PC, Brandenburg S, Meder B, Edelmann F, Vlachopoulos C, Anastasakis A, Filippatos G, Prappa E, Efthimiadis G, Sepp R, Merkely B, Adalsteinsdottir B, Arad M, Halabi M, Zwas D, Assali A, Piltz X, Olivotto I, Piepoli M, Ammirati E, Todiere G, Angela Losi M, Sinagra G, Metra M, Volterrani M, Brunetti N, Crotti L, Amin A, Michels M, Knackstedt C, Wojakowski W, Krakowiak B, Guerreiro R, Toste Batista A, Mesquita Bastos JA, Aguiar Rosa S, Azevedo O, Peña-Peña ML, Garcia-Pavia P, Barriales-Villa R, Rincon Diaz LM, Hidalgo Urbano RJ, Garcia Alvarez A, de Antonio Ferrer M, Garcia Pinilla JM, Espinosa Castro MA, Restrepo Cordoba MA, Gimeno Blanes JR, Quesada R, Ripoll Vera TV, Elliott P, Maria Choy A, Coats CJ, Cooper R, Raman B, Pantazis A, Tome Esteban MT, Masri A, Bhatia A, Sherrid MV, Rowin EJ, Choudhury L, MacNamara J, Sikand N, Nassif ME, Arora P, Owens AT, Lakdawala N, Tower-Rader A, Afshar K, Saberi S, Nagueh S, Phelan D, Martinez MW, Hazday M, Pino Moreno J, Wang J, Wharton R, Rader F, Hannawi B, Bering P, Moss N, Bilen O, Ravi S, Flanagan M, Galazka P, Wong T, Desai M, Geske J, Halbmaier K, Stehlik J, Brinkley M, Zenker M, Atkins J, Harper M, Collado E, Markowitz J, Naidu S, Darlington A, Xie L, Weiner S, Ravichandran A, Doll J, Bianco C, McDonald D, Lander B, Roldan P, Abraham T, Kelly J, Jani S, Silva Enciso J, Hama Amin A, Malhotra S, French W, Murray D, Mudd J, Costabel JP, Salomone O, Selvanayagam J, McKenzie S, Patel V, Figueiredo E, Antunes M, Barros Correia E, Alvarez Ramires FJ, Vellosa Schwartzmann P, Kerr Saraiva JF, Pimentel Filho P, Eduardo Ritt L, Vinicius Simões M, Batista de Lima CE, da Consolação Moreira M, Tadros R, Zieroth S, Caddell A, Tyrrell B, Costa Vitali A, Zhao X, Jin W, Ge J, Hou A, Zhang Y, Yuan Z, Li L, Li Y, Li X, Zheng Y, Dong Y, Ma W, H. Poulsen S, Jakob Thune J, Morris Hey T, Ricci JE, Habib G, Logeart D, Piriou N, Hagege A, Lairez O, Roubille F, Reant P, Schulze PC, Brandenburg S, Meder B, Edelmann F, Vlachopoulos C, Anastasakis A, Filippatos G, Prappa E, Efthimiadis G, Sepp R, Merkely B, Adalsteinsdottir B, Arad M, Halabi M, Zwas D, Assali A, Piltz X, Olivotto I, Piepoli M, Ammirati E, Todiere G, Angela Losi M, Sinagra G, Metra M, Volterrani M, Brunetti N, Crotti L, Amin A, Michels M, Knackstedt C, Wojakowski W, Krakowiak B, Guerreiro R, Toste Batista A, Mesquita Bastos JA, Aguiar Rosa S, Azevedo O, Peña-Peña ML, Garcia-Pavia P, Barriales-Villa R, Rincon Diaz LM, Hidalgo Urbano RJ, Garcia Alvarez A, de Antonio Ferrer M, Garcia Pinilla JM, Espinosa Castro MA, Restrepo Cordoba MA, Gimeno Blanes JR, Quesada R, Ripoll Vera TV, Elliott P, Maria Choy A, Coats CJ, Cooper R, Raman B, Pantazis A, Tome Esteban MT, Masri A, Bhatia A, Sherrid MV, Rowin EJ, Choudhury L, MacNamara J, Sikand N, Nassif ME, Arora P, Owens AT, Lakdawala N, Tower-Rader A, Afshar K, Saberi S, Nagueh S, Phelan D, Martinez MW, Hazday M, Pino Moreno J, Wang J, Wharton R, Rader F, Hannawi B, Bering P, Moss N, Bilen O, Ravi S, Flanagan M, Galazka P, Wong T, Desai M, Geske J, Halbmaier K, Stehlik J, Brinkley M, Zenker M, Atkins J, Harper M, Collado E, Markowitz J, Naidu S, Darlington A, Xie L, Weiner S, Ravichandran A, Doll J, Bianco C, McDonald D, Lander B, Roldan P, Abraham T, Kelly J, Jani S, Silva Enciso J, Hama Amin A, Malhotra S, French W, Murray D, Mudd J. Global Efficacy of Aficamten in Nonobstructive Hypertrophic Cardiomyopathy: Results From ACACIA-HCM. Circulation 2026, CIRCULATIONAHA.126.082026. DOI: 10.1161/CIRCULATIONAHA.126.082026.
    Peer-Reviewed Original Research

2025

2024

Academic Achievements & Community Involvement

Activities

  • activity

    JACC Heart Failure

  • activity

    Yale University School of Medicine, Department of Medicine Intern Selection Committee

  • activity

    Heart Failure Society of America

  • activity

    American College of Cardiology

  • activity

    Yale Heart Failure Symposium

Honors

  • honor

    Fellow of the American College of Cardiology

  • honor

    Teacher of the Year Award (Sub-Specialty)

Clinical Care

Overview

Nikhil Victor Sikand, MD, is a cardiovascular medicine specialist with subspecialty training in advanced heart failure, including congestive heart failure (CHF), heart transplantation, cardiomyopathies, and mechanical circulatory support.

He manages patients needing heart transplantation, left ventricular assist devices (LVADs) and temporary mechanical circulatory support devices as well as patients with heart failure with reduced and preserved ejection fraction and cardiomyopathies. He is also a specialist in the Yale Hypertrophic Cardiomyopathy Center of Excellence and acts as the medical director the Heart Transplant and Durable Mechanical Circulatory Support programs.

Dr. Sikand is an assistant professor of medicine at Yale School of Medicine and a clinician-educator. He is associate program director of the Advanced Heart Failure and Transplant Cardiology fellowship program. He has received awards for his teaching and commitment to medical education.

His research interests include hypertrophic cardiomyopathy, heart transplantation and mechanical circulatory support, quality improvement in medical education and systems-based approaches to improving heart failure outcomes. He is the principal investigator or subinvestigator on several ongoing clinical trials at Yale.

Dr. Sikand completed medical school at Tufts University School of Medicine followed by residency training at Yale School of Medicine and Yale New Haven Hospital, and fellowship training at NYU Grossman School of Medicine. He is board certified in internal medicine, cardiovascular medicine, advanced heart failure and transplant cardiology, and comprehensive echocardiography.

Clinical Specialties

Heart Failure; Cardiovascular Medicine

Fact Sheets

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Get In Touch

Contacts

Appointment Number
Mailing Address

Cardiovascular Medicine

333 Cedar Street, Box 208017

New Haven, CT 06520-8017

United States

Locations

  • Patient Care Locations

    Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.