Maria Nagy, PhD
Associate Research Scientist in GeneticsCards
Appointments
Genetics
Primary
Contact Info
Genetics
333 Cedar Street, SHM I323
New Haven, CT 06511
United States
About
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Titles
Associate Research Scientist in Genetics
Appointments
Education & Training
- PhD
- Kansas State University, Department of Biochemistry, Biochemistry (2008)
- MSc
- Babes-Bolyai University, Faculty of Physics, Quantum Condensed State and Field Theory (1998)
- BS
- Babes-Bolyai University, Faculty of Physics, Physics (1997)
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Maria Nagy's published research.
Publications Timeline
A big-picture view of Maria Nagy's research output by year.
Arthur Horwich, MD
Weiming Ni, PhD
Francesc Lopez-Giraldez, PhD
Joan Steitz, PhD
Shervin S. Takyar, MD, PhD
15Publications
419Citations
Publications
2019
Hsp110 mitigates α-synuclein pathology in vivo
Taguchi YV, Gorenberg EL, Nagy M, Thrasher D, Fenton WA, Volpicelli-Daley L, Horwich AL, Chandra SS. Hsp110 mitigates α-synuclein pathology in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 24310-24316. PMID: 31685606, PMCID: PMC6883785, DOI: 10.1073/pnas.1903268116.Peer-Reviewed Original ResearchCitationsAltmetric
2016
Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice
Hadzipasic M, Ni W, Nagy M, Steenrod N, McGinley MJ, Kaushal A, Thomas E, McCormick DA, Horwich AL. Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: e7600-e7609. PMID: 27821773, PMCID: PMC5127366, DOI: 10.1073/pnas.1616832113.Peer-Reviewed Original ResearchCitationsAltmetricExtended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110
Nagy M, Fenton WA, Li D, Furtak K, Horwich AL. Extended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 5424-5428. PMID: 27114530, PMCID: PMC4868459, DOI: 10.1073/pnas.1604885113.Peer-Reviewed Original ResearchCitationsAltmetric
2015
Proteomics and Transcriptomics of BJAB Cells Expressing the Epstein-Barr Virus Noncoding RNAs EBER1 and EBER2
Pimienta G, Fok V, Haslip M, Nagy M, Takyar S, Steitz JA. Proteomics and Transcriptomics of BJAB Cells Expressing the Epstein-Barr Virus Noncoding RNAs EBER1 and EBER2. PLOS ONE 2015, 10: e0124638. PMID: 26121143, PMCID: PMC4487896, DOI: 10.1371/journal.pone.0124638.Peer-Reviewed Original ResearchCitationsAltmetric
2014
Selective degeneration of a physiological subtype of spinal motor neuron in mice with SOD1-linked ALS
Hadzipasic M, Tahvildari B, Nagy M, Bian M, Horwich AL, McCormick DA. Selective degeneration of a physiological subtype of spinal motor neuron in mice with SOD1-linked ALS. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 16883-16888. PMID: 25385594, PMCID: PMC4250117, DOI: 10.1073/pnas.1419497111.Peer-Reviewed Original ResearchCitationsAltmetricAbsence of lipofuscin in motor neurons of SOD1-linked ALS mice
Bandyopadhyay U, Nagy M, Fenton WA, Horwich AL. Absence of lipofuscin in motor neurons of SOD1-linked ALS mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 11055-11060. PMID: 25024188, PMCID: PMC4121794, DOI: 10.1073/pnas.1409314111.Peer-Reviewed Original ResearchCitationsMeSH KeywordsAdaptor Proteins, Signal TransducingAmino Acid SubstitutionAmyotrophic Lateral SclerosisAnimalsAutophagyAutophagy-Related Protein-1 HomologHeat-Shock ProteinsHumansLipofuscinLysosomesMechanistic Target of Rapamycin Complex 1MiceMice, TransgenicMicrotubule-Associated ProteinsMotor NeuronsMultiprotein ComplexesMutation, MissenseProtein Serine-Threonine KinasesSequestosome-1 ProteinSuperoxide DismutaseSuperoxide Dismutase-1TOR Serine-Threonine KinasesProduction of RNA for Transcriptomic Analysis from Mouse Spinal Cord Motor Neuron Cell Bodies by Laser Capture Microdissection
Bandyopadhyay U, Fenton WA, Horwich AL, Nagy M. Production of RNA for Transcriptomic Analysis from Mouse Spinal Cord Motor Neuron Cell Bodies by Laser Capture Microdissection. Journal Of Visualized Experiments 2014, 51168. PMID: 24457537, PMCID: PMC4089401, DOI: 10.3791/51168.Peer-Reviewed Original ResearchCitationsAltmetric
2013
Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm
Song Y, Nagy M, Ni W, Tyagi NK, Fenton WA, López-Giráldez F, Overton JD, Horwich AL, Brady ST. Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 5428-5433. PMID: 23509252, PMCID: PMC3619309, DOI: 10.1073/pnas.1303279110.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsAnimalsAxonal TransportBacterial ProteinsDecapodiformesGene Expression ProfilingHSP110 Heat-Shock ProteinsHumansLuminescent ProteinsMAP Kinase Kinase Kinase 5MiceMice, TransgenicMutation, Missensep38 Mitogen-Activated Protein KinasesPhosphorylationProtein FoldingProteomicsRecombinant Fusion ProteinsSpinal CordSuperoxide DismutaseSuperoxide Dismutase-1Transport VesiclesRNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse
Bandyopadhyay U, Cotney J, Nagy M, Oh S, Leng J, Mahajan M, Mane S, Fenton WA, Noonan JP, Horwich AL. RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse. PLOS ONE 2013, 8: e53575. PMID: 23301088, PMCID: PMC3536741, DOI: 10.1371/journal.pone.0053575.Peer-Reviewed Original ResearchCitationsAltmetric
2012
Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency.
Zhang T, Ploetz EA, Nagy M, Doyle SM, Wickner S, Smith PE, Zolkiewski M. Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency. Proteins 2012, 80: 2758-68. PMID: 22890624, DOI: 10.1002/prot.24159.Peer-Reviewed Original Research
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Genetics
333 Cedar Street, SHM I323
New Haven, CT 06511
United States