Qinfang Liu
Postdoctoral Associate (Neuroscience)About
Research
Publications
2024
CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration.
Liu Q, Huang B, Guiberson NGL, Chen S, Zhu D, Ma G, Ma XM, Crittenden JR, Yu J, Graybiel AM, Dawson TM, Dawson VL, Xiong Y. CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration. Sci Adv 2024, 10: eadn5417. PMID: 39576856, DOI: 10.1126/sciadv.adn5417.Peer-Reviewed Original Research
2023
Regulation of LRRK2 mRNA stability by ATIC and its substrate AICAR through ARE-mediated mRNA decay in Parkinson's disease.
Liu Q, Zhu D, Li N, Chen S, Hu L, Yu J, Xiong Y. Regulation of LRRK2 mRNA stability by ATIC and its substrate AICAR through ARE-mediated mRNA decay in Parkinson's disease. EMBO J 2023, 42: e113410. PMID: 37366237, DOI: 10.15252/embj.2022113410.Peer-Reviewed Original Research
2022
Myotubularin functions through actomyosin to interact with the Hippo pathway.
Hu L, Brichalli W, Li N, Chen S, Cheng Y, Liu Q, Xiong Y, Yu J. Myotubularin functions through actomyosin to interact with the Hippo pathway. EMBO Rep 2022, 23: e55851. PMID: 36285521, DOI: 10.15252/embr.202255851.Peer-Reviewed Original ResearchDifferent serotypes of Escherichia coli flagellin exert identical adjuvant effects.
Pang S, Wu W, Liu Q, Zhu G, Duan Q. Different serotypes of Escherichia coli flagellin exert identical adjuvant effects. BMC Vet Res 2022, 18: 308. PMID: 35953794, DOI: 10.1186/s12917-022-03412-3.Peer-Reviewed Original Research
2021
Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration.
Liu Q, Bautista-Gomez J, Higgins DA, Yu J, Xiong Y. Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration. Sci Signal 2021, 14 PMID: 34315807, DOI: 10.1126/scisignal.abg3555.Peer-Reviewed Original Research
2019
Cross-Species Genome-Wide Analysis Reveals Molecular and Functional Diversity of the Unconventional Interferon-ω Subtype.
Shields LE, Jennings J, Liu Q, Lee J, Ma W, Blecha F, Miller LC, Sang Y. Cross-Species Genome-Wide Analysis Reveals Molecular and Functional Diversity of the Unconventional Interferon-ω Subtype. Front Immunol 2019, 10: 1431. PMID: 31293589, DOI: 10.3389/fimmu.2019.01431.Peer-Reviewed Original ResearchHeadcase and Unkempt Regulate Tissue Growth and Cell Cycle Progression in Response to Nutrient Restriction.
Li N, Liu Q, Xiong Y, Yu J. Headcase and Unkempt Regulate Tissue Growth and Cell Cycle Progression in Response to Nutrient Restriction. Cell Rep 2019, 26: 733-747.e3. PMID: 30650363, DOI: 10.1016/j.celrep.2018.12.086.Peer-Reviewed Original Research
2018
Genome-wide analysis of differentially expressed genes and the modulation of PEDV infection in Vero E6 cells.
Zhang H, Liu Q, Su W, Wang J, Sun Y, Zhang J, Shang K, Chen Z, Cheng S, Wu H. Genome-wide analysis of differentially expressed genes and the modulation of PEDV infection in Vero E6 cells. Microb Pathog 2018, 117: 247-254. PMID: 29408315, DOI: 10.1016/j.micpath.2018.02.004.Peer-Reviewed Original ResearchRobust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.
Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proc Natl Acad Sci U S A 2018, 115: 1635-1640. PMID: 29386392, DOI: 10.1073/pnas.1712648115.Peer-Reviewed Original Research
2017
Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.
Huang L, Xiong T, Yu H, Zhang Q, Zhang K, Li C, Hu L, Zhang Y, Zhang L, Liu Q, Wang S, He X, Bu Z, Cai X, Cui S, Li J, Weng C. Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex. The Biochemical Journal 2017, 474: 2051-2065. PMID: 28487378, PMCID: PMC5465970, DOI: 10.1042/BCJ20161037.Peer-Reviewed Original Research