2012
Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAs
Brown JA, Valenstein ML, Yario TA, Tycowski KT, Steitz JA. Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAs. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 19202-19207. PMID: 23129630, PMCID: PMC3511071, DOI: 10.1073/pnas.1217338109.Peer-Reviewed Original ResearchConceptsRich internal loopMetastasis-associated lung adenocarcinoma transcript 1Rich tractSarcoma-associated herpesvirusDuplex-triplex junctionsTriple helical structureCellular noncoding RNAsNuclear retention elementBase triplesInternal loopKaposi's sarcoma-associated herpesvirusU base triplesPAN RNATriple helixNoncoding RNAsNuclear RNAThermal denaturation profilesReporter RNALung adenocarcinoma transcript 1C nucleotidesC base pairsMolecular mechanismsUnpaired nucleotidesBase pairsRNA
1979
The 3′ terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1
Yuan R, Steitz J, Moore P, Crothers D. The 3′ terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1. Nucleic Acids Research 1979, 7: 2399-2418. PMID: 392471, PMCID: PMC342392, DOI: 10.1093/nar/7.8.2399.Peer-Reviewed Original Research
1974
Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA
Gralla J, Steitz J, Crothers D. Direct physical evidence for secondary structure in an isolated fragment of R17 bacteriophage mRNA. Nature 1974, 248: 204-208. PMID: 4819414, DOI: 10.1038/248204a0.Peer-Reviewed Original ResearchHigh resolution proton NMR study of an isolated fragment of R17 bacteriophage mRNA
HILBERS CW, SHULMAN RG, YAMANE T, STEITZ JA. High resolution proton NMR study of an isolated fragment of R17 bacteriophage mRNA. Nature 1974, 248: 225-226. PMID: 4819416, DOI: 10.1038/248225a0.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceColiphagesHot TemperatureMagnetic Resonance SpectroscopyNucleic Acid ConformationNucleic Acid DenaturationOligonucleotidesRNA VirusesRNA, MessengerRNA, ViralConceptsHelical regionBase pairsBase pairingWatson-Crick base pairingIsolated fragmentsSecondary structureNMR spectraModel systemNuclear magnetic resonance spectraHigh-resolution nuclear magnetic resonance spectraNucleic acidsHydrogen-bonded protonsMagnetic resonance spectraProton NMR studiesAdjacent basesLeaf modelFragmentsNH protonsNMR studiesTRNAResonance spectraHigh-resolution proton NMR studiesHelixPairingGuanine
1973
Genome independent specificity of DNA-directed f Met-dipeptide synthesis
Condit RC, Goldberg M, Steitz JA. Genome independent specificity of DNA-directed f Met-dipeptide synthesis. Journal Of Molecular Biology 1973, 75: 449-454. PMID: 4580686, DOI: 10.1016/0022-2836(73)90036-3.Peer-Reviewed Original Research