Welcome to the Steitz Lab
Research
Noncoding RNA-protein complexes (ncRNPs) are ubiquitous in eukaryotic cells and inhabit specific cellular compartments. The most famous noncoding nuclear RNPs (snRNPs) participate in pre-mRNA splicing by recognizing important intron signals and assembling to form an active splicing complex called a spliceosome. There are many other kinds, including those where the RNA is made by an infecting virus.