Welcome to the Steitz Lab

Home image

Research

Noncoding RNA-protein complexes (ncRNPs) are ubiquitous in eukaryotic cells and inhabit specific cellular compartments. The most famous noncoding nuclear RNPs (snRNPs) participate in pre-mRNA splicing by recognizing important intron signals and assembling to form an active splicing complex called a spliceosome. There are many other kinds, including those where the RNA is made by an infecting virus.

Steitz Lab

Joan A Steitz, PhD

Sterling Professor of Molecular Biophysics and Biochemistry

Contact Info

Office 203.737.4418
Fax 203.624.8213

[{"created_at":"Thu Jun 30 23:13:08 +0000 2016","id":748655641237983233,"id_str":"748655641237983233","full_text":"RT @phil_bevilacqua: Bridging the gap between in vitro and in vivo RNA folding #BevilacquaLab https:\/\/t.co\/sA68cuoalo https:\/\/t.co\/bggtKG3m\u2026","truncated":false,"display_text_range":[0,140],"entities":{"hashtags":[{"text":"BevilacquaLab","indices":[79,93]}],"symbols":[],"user_mentions":[{"screen_name":"phil_bevilacqua","name":"BevilacquaLab","id":3108939357,"id_str":"3108939357","indices":[3,19]}],"urls":[{"url":"https:\/\/t.co\/sA68cuoalo","expanded_url":"http:\/\/journals.cambridge.org\/action\/displayAbstract?fromPage=online&aid=10379711&fulltextType=RV&fileId=S003358351600007X","display_url":"journals.cambridge.org\/action\/display\u2026","indices":[94,117]}]},"source":"\u003ca href=\"http:\/\/twitter.com\" rel=\"nofollow\"\u003eTwitter Web Client\u003c\/a\u003e","in_reply_to_status_id":null,"in_reply_to_status_id_str":null,"in_reply_to_user_id":null,"in_reply_to_user_id_str":null,"in_reply_to_screen_name":null,"user":{"id":2904264497,"id_str":"2904264497","name":"Joan Steitz Lab","screen_name":"SteitzLab","location":"Yale University","description":"We study RNA Biology using a variety of approaches.","url":"http:\/\/t.co\/SjRluoyTrO","entities":{"url":{"urls":[{"url":"http:\/\/t.co\/SjRluoyTrO","expanded_url":"http:\/\/medicine.yale.edu\/lab\/steitz\/","display_url":"medicine.yale.edu\/lab\/steitz\/","indices":[0,22]}]},"description":{"urls":[]}},"protected":false,"followers_count":771,"friends_count":120,"listed_count":15,"created_at":"Wed Dec 03 20:40:39 +0000 2014","favourites_count":41,"utc_offset":null,"time_zone":null,"geo_enabled":false,"verified":false,"statuses_count":49,"lang":"en","contributors_enabled":false,"is_translator":false,"is_translation_enabled":false,"profile_background_color":"C0DEED","profile_background_image_url":"http:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_image_url_https":"https:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_tile":false,"profile_image_url":"http:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_image_url_https":"https:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_link_color":"1DA1F2","profile_sidebar_border_color":"C0DEED","profile_sidebar_fill_color":"DDEEF6","profile_text_color":"333333","profile_use_background_image":true,"has_extended_profile":false,"default_profile":true,"default_profile_image":false,"following":null,"follow_request_sent":null,"notifications":null,"translator_type":"none"},"geo":null,"coordinates":null,"place":null,"contributors":null,"retweeted_status":{"created_at":"Tue Jun 28 03:35:45 +0000 2016","id":747634564579868672,"id_str":"747634564579868672","full_text":"Bridging the gap between in vitro and in vivo RNA folding #BevilacquaLab https:\/\/t.co\/sA68cuoalo https:\/\/t.co\/bggtKG3mc8","truncated":false,"display_text_range":[0,96],"entities":{"hashtags":[{"text":"BevilacquaLab","indices":[58,72]}],"symbols":[],"user_mentions":[],"urls":[{"url":"https:\/\/t.co\/sA68cuoalo","expanded_url":"http:\/\/journals.cambridge.org\/action\/displayAbstract?fromPage=online&aid=10379711&fulltextType=RV&fileId=S003358351600007X","display_url":"journals.cambridge.org\/action\/display\u2026","indices":[73,96]}],"media":[{"id":747634531201617920,"id_str":"747634531201617920","indices":[97,120],"media_url":"http:\/\/pbs.twimg.com\/media\/CmAhpR4WkAAMxv6.jpg","media_url_https":"https:\/\/pbs.twimg.com\/media\/CmAhpR4WkAAMxv6.jpg","url":"https:\/\/t.co\/bggtKG3mc8","display_url":"pic.twitter.com\/bggtKG3mc8","expanded_url":"https:\/\/twitter.com\/phil_bevilacqua\/status\/747634564579868672\/photo\/1","type":"photo","sizes":{"thumb":{"w":150,"h":150,"resize":"crop"},"small":{"w":680,"h":236,"resize":"fit"},"medium":{"w":943,"h":327,"resize":"fit"},"large":{"w":943,"h":327,"resize":"fit"}}}]},"extended_entities":{"media":[{"id":747634531201617920,"id_str":"747634531201617920","indices":[97,120],"media_url":"http:\/\/pbs.twimg.com\/media\/CmAhpR4WkAAMxv6.jpg","media_url_https":"https:\/\/pbs.twimg.com\/media\/CmAhpR4WkAAMxv6.jpg","url":"https:\/\/t.co\/bggtKG3mc8","display_url":"pic.twitter.com\/bggtKG3mc8","expanded_url":"https:\/\/twitter.com\/phil_bevilacqua\/status\/747634564579868672\/photo\/1","type":"photo","sizes":{"thumb":{"w":150,"h":150,"resize":"crop"},"small":{"w":680,"h":236,"resize":"fit"},"medium":{"w":943,"h":327,"resize":"fit"},"large":{"w":943,"h":327,"resize":"fit"}}}]},"source":"\u003ca href=\"http:\/\/twitter.com\" rel=\"nofollow\"\u003eTwitter Web Client\u003c\/a\u003e","in_reply_to_status_id":null,"in_reply_to_status_id_str":null,"in_reply_to_user_id":null,"in_reply_to_user_id_str":null,"in_reply_to_screen_name":null,"user":{"id":3108939357,"id_str":"3108939357","name":"BevilacquaLab","screen_name":"phil_bevilacqua","location":"Penn State","description":"RNA chemistry and biology, ribozyme mechanism, RNA in vivo, early Earth and RNA","url":"http:\/\/t.co\/Xnwdo4eDcy","entities":{"url":{"urls":[{"url":"http:\/\/t.co\/Xnwdo4eDcy","expanded_url":"http:\/\/sites.psu.edu\/bevilacqua","display_url":"sites.psu.edu\/bevilacqua","indices":[0,22]}]},"description":{"urls":[]}},"protected":false,"followers_count":938,"friends_count":496,"listed_count":13,"created_at":"Mon Mar 23 23:56:00 +0000 2015","favourites_count":332,"utc_offset":null,"time_zone":null,"geo_enabled":false,"verified":false,"statuses_count":264,"lang":"en","contributors_enabled":false,"is_translator":false,"is_translation_enabled":false,"profile_background_color":"000000","profile_background_image_url":"http:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_image_url_https":"https:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_tile":false,"profile_image_url":"http:\/\/pbs.twimg.com\/profile_images\/665711106044788736\/stiZ72l__normal.jpg","profile_image_url_https":"https:\/\/pbs.twimg.com\/profile_images\/665711106044788736\/stiZ72l__normal.jpg","profile_banner_url":"https:\/\/pbs.twimg.com\/profile_banners\/3108939357\/1522000908","profile_link_color":"9266CC","profile_sidebar_border_color":"000000","profile_sidebar_fill_color":"000000","profile_text_color":"000000","profile_use_background_image":false,"has_extended_profile":false,"default_profile":false,"default_profile_image":false,"following":null,"follow_request_sent":null,"notifications":null,"translator_type":"none"},"geo":null,"coordinates":null,"place":null,"contributors":null,"is_quote_status":false,"retweet_count":9,"favorite_count":19,"favorited":false,"retweeted":false,"possibly_sensitive":false,"lang":"en"},"is_quote_status":false,"retweet_count":9,"favorite_count":0,"favorited":false,"retweeted":false,"possibly_sensitive":false,"lang":"en"},{"created_at":"Thu Jun 30 23:11:38 +0000 2016","id":748655263398273025,"id_str":"748655263398273025","full_text":"@theNASciences Thank you!","truncated":false,"display_text_range":[15,25],"entities":{"hashtags":[],"symbols":[],"user_mentions":[{"screen_name":"theNASciences","name":"NatlAcad of Sciences","id":2293415520,"id_str":"2293415520","indices":[0,14]}],"urls":[]},"source":"\u003ca href=\"http:\/\/twitter.com\" rel=\"nofollow\"\u003eTwitter Web Client\u003c\/a\u003e","in_reply_to_status_id":748601301764825089,"in_reply_to_status_id_str":"748601301764825089","in_reply_to_user_id":2293415520,"in_reply_to_user_id_str":"2293415520","in_reply_to_screen_name":"theNASciences","user":{"id":2904264497,"id_str":"2904264497","name":"Joan Steitz Lab","screen_name":"SteitzLab","location":"Yale University","description":"We study RNA Biology using a variety of approaches.","url":"http:\/\/t.co\/SjRluoyTrO","entities":{"url":{"urls":[{"url":"http:\/\/t.co\/SjRluoyTrO","expanded_url":"http:\/\/medicine.yale.edu\/lab\/steitz\/","display_url":"medicine.yale.edu\/lab\/steitz\/","indices":[0,22]}]},"description":{"urls":[]}},"protected":false,"followers_count":771,"friends_count":120,"listed_count":15,"created_at":"Wed Dec 03 20:40:39 +0000 2014","favourites_count":41,"utc_offset":null,"time_zone":null,"geo_enabled":false,"verified":false,"statuses_count":49,"lang":"en","contributors_enabled":false,"is_translator":false,"is_translation_enabled":false,"profile_background_color":"C0DEED","profile_background_image_url":"http:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_image_url_https":"https:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_tile":false,"profile_image_url":"http:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_image_url_https":"https:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_link_color":"1DA1F2","profile_sidebar_border_color":"C0DEED","profile_sidebar_fill_color":"DDEEF6","profile_text_color":"333333","profile_use_background_image":true,"has_extended_profile":false,"default_profile":true,"default_profile_image":false,"following":null,"follow_request_sent":null,"notifications":null,"translator_type":"none"},"geo":null,"coordinates":null,"place":null,"contributors":null,"is_quote_status":false,"retweet_count":0,"favorite_count":0,"favorited":false,"retweeted":false,"lang":"en"},{"created_at":"Sat Jun 25 15:10:26 +0000 2016","id":746722223319310336,"id_str":"746722223319310336","full_text":"Host miRNA degradation by a viral ncRNA requires an unstructured interacting region: https:\/\/t.co\/5gNJsjyiJs","truncated":false,"display_text_range":[0,108],"entities":{"hashtags":[],"symbols":[],"user_mentions":[],"urls":[{"url":"https:\/\/t.co\/5gNJsjyiJs","expanded_url":"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27335146","display_url":"ncbi.nlm.nih.gov\/pubmed\/27335146","indices":[85,108]}]},"source":"\u003ca href=\"https:\/\/mobile.twitter.com\" rel=\"nofollow\"\u003eTwitter Lite\u003c\/a\u003e","in_reply_to_status_id":null,"in_reply_to_status_id_str":null,"in_reply_to_user_id":null,"in_reply_to_user_id_str":null,"in_reply_to_screen_name":null,"user":{"id":2904264497,"id_str":"2904264497","name":"Joan Steitz Lab","screen_name":"SteitzLab","location":"Yale University","description":"We study RNA Biology using a variety of approaches.","url":"http:\/\/t.co\/SjRluoyTrO","entities":{"url":{"urls":[{"url":"http:\/\/t.co\/SjRluoyTrO","expanded_url":"http:\/\/medicine.yale.edu\/lab\/steitz\/","display_url":"medicine.yale.edu\/lab\/steitz\/","indices":[0,22]}]},"description":{"urls":[]}},"protected":false,"followers_count":771,"friends_count":120,"listed_count":15,"created_at":"Wed Dec 03 20:40:39 +0000 2014","favourites_count":41,"utc_offset":null,"time_zone":null,"geo_enabled":false,"verified":false,"statuses_count":49,"lang":"en","contributors_enabled":false,"is_translator":false,"is_translation_enabled":false,"profile_background_color":"C0DEED","profile_background_image_url":"http:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_image_url_https":"https:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_tile":false,"profile_image_url":"http:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_image_url_https":"https:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_link_color":"1DA1F2","profile_sidebar_border_color":"C0DEED","profile_sidebar_fill_color":"DDEEF6","profile_text_color":"333333","profile_use_background_image":true,"has_extended_profile":false,"default_profile":true,"default_profile_image":false,"following":null,"follow_request_sent":null,"notifications":null,"translator_type":"none"},"geo":null,"coordinates":null,"place":null,"contributors":null,"is_quote_status":false,"retweet_count":5,"favorite_count":8,"favorited":false,"retweeted":false,"possibly_sensitive":false,"lang":"en"},{"created_at":"Wed Apr 06 21:27:42 +0000 2016","id":717826136584036352,"id_str":"717826136584036352","full_text":"Grats to Anna on the new job! https:\/\/t.co\/u1sPtUrgat","truncated":false,"display_text_range":[0,53],"entities":{"hashtags":[],"symbols":[],"user_mentions":[],"urls":[],"media":[{"id":717826135975981056,"id_str":"717826135975981056","indices":[30,53],"media_url":"http:\/\/pbs.twimg.com\/media\/CfY7EUVW8AAzLA1.jpg","media_url_https":"https:\/\/pbs.twimg.com\/media\/CfY7EUVW8AAzLA1.jpg","url":"https:\/\/t.co\/u1sPtUrgat","display_url":"pic.twitter.com\/u1sPtUrgat","expanded_url":"https:\/\/twitter.com\/SteitzLab\/status\/717826136584036352\/photo\/1","type":"photo","sizes":{"thumb":{"w":150,"h":150,"resize":"crop"},"large":{"w":640,"h":480,"resize":"fit"},"medium":{"w":640,"h":480,"resize":"fit"},"small":{"w":640,"h":480,"resize":"fit"}}}]},"extended_entities":{"media":[{"id":717826135975981056,"id_str":"717826135975981056","indices":[30,53],"media_url":"http:\/\/pbs.twimg.com\/media\/CfY7EUVW8AAzLA1.jpg","media_url_https":"https:\/\/pbs.twimg.com\/media\/CfY7EUVW8AAzLA1.jpg","url":"https:\/\/t.co\/u1sPtUrgat","display_url":"pic.twitter.com\/u1sPtUrgat","expanded_url":"https:\/\/twitter.com\/SteitzLab\/status\/717826136584036352\/photo\/1","type":"photo","sizes":{"thumb":{"w":150,"h":150,"resize":"crop"},"large":{"w":640,"h":480,"resize":"fit"},"medium":{"w":640,"h":480,"resize":"fit"},"small":{"w":640,"h":480,"resize":"fit"}}}]},"source":"\u003ca href=\"http:\/\/twitter.com\" rel=\"nofollow\"\u003eTwitter Web Client\u003c\/a\u003e","in_reply_to_status_id":null,"in_reply_to_status_id_str":null,"in_reply_to_user_id":null,"in_reply_to_user_id_str":null,"in_reply_to_screen_name":null,"user":{"id":2904264497,"id_str":"2904264497","name":"Joan Steitz Lab","screen_name":"SteitzLab","location":"Yale University","description":"We study RNA Biology using a variety of approaches.","url":"http:\/\/t.co\/SjRluoyTrO","entities":{"url":{"urls":[{"url":"http:\/\/t.co\/SjRluoyTrO","expanded_url":"http:\/\/medicine.yale.edu\/lab\/steitz\/","display_url":"medicine.yale.edu\/lab\/steitz\/","indices":[0,22]}]},"description":{"urls":[]}},"protected":false,"followers_count":771,"friends_count":120,"listed_count":15,"created_at":"Wed Dec 03 20:40:39 +0000 2014","favourites_count":41,"utc_offset":null,"time_zone":null,"geo_enabled":false,"verified":false,"statuses_count":49,"lang":"en","contributors_enabled":false,"is_translator":false,"is_translation_enabled":false,"profile_background_color":"C0DEED","profile_background_image_url":"http:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_image_url_https":"https:\/\/abs.twimg.com\/images\/themes\/theme1\/bg.png","profile_background_tile":false,"profile_image_url":"http:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_image_url_https":"https:\/\/pbs.twimg.com\/profile_images\/541988326727626752\/Keqv89wM_normal.png","profile_link_color":"1DA1F2","profile_sidebar_border_color":"C0DEED","profile_sidebar_fill_color":"DDEEF6","profile_text_color":"333333","profile_use_background_image":true,"has_extended_profile":false,"default_profile":true,"default_profile_image":false,"following":null,"follow_request_sent":null,"notifications":null,"translator_type":"none"},"geo":null,"coordinates":null,"place":null,"contributors":null,"is_quote_status":false,"retweet_count":0,"favorite_count":3,"favorited":false,"retweeted":false,"possibly_sensitive":false,"lang":"en"}]

Twitter Feed

@SteitzLab

Follow @SteitzLab