2004
Transmission of enterotropic mouse hepatitis virus from immunocompetent and immunodeficient mice.
Compton SR, Ball-Goodrich LJ, Paturzo FX, Macy JD. Transmission of enterotropic mouse hepatitis virus from immunocompetent and immunodeficient mice. Comparative Medicine 2004, 54: 29-35. PMID: 15027615.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Outbred StrainsFecesFemaleHepatitis, Viral, AnimalImmunocompetenceImmunocompromised HostInfectious Disease Transmission, VerticalMiceMice, Inbred StrainsMurine hepatitis virusReverse Transcriptase Polymerase Chain ReactionRNA, ViralRodent DiseasesSentinel SurveillanceSpecies SpecificityVirus SheddingConceptsCell-deficient miceEnterotropic mouse hepatitis virusT cell-deficient miceMouse hepatitis virusInfected miceIntestinal infectionsC57BL/6 miceHepatitis virusB cell-deficient miceViral RNABALB/c miceSevere disseminated diseaseNon-infectious RNADisseminated diseaseNaive miceC miceMHV infectionImmunodeficient miceSentinel miceBALB/ cViral transmissionInfectionMiceVirus RNAWeeks
2003
Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus.
Compton SR, Ball-Goodrich LJ, Zeiss CJ, Johnson LK, Johnson EA, Macy JD. Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with Helicobacter hepaticus. Comparative Medicine 2003, 53: 197-206. PMID: 12784855.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCoronavirus InfectionsDNA, BacterialHelicobacter hepaticusHelicobacter InfectionsHepatitis, Viral, AnimalIn Situ HybridizationInterferon-gammaLiverMiceMice, Inbred C3HMice, KnockoutMurine hepatitis virusReverse Transcriptase Polymerase Chain ReactionRNA, ViralConceptsIFN-gamma KO miceGamma interferon-deficient miceMouse hepatitis virusInterferon-deficient miceDevelopment of peritonitisKO miceH. hepaticusMultisystemic infectionHelicobacter hepaticusMouse hepatitis virus infectionHepatitis virus infectionAberrant immune responseSelf-limiting infectionMinimal pathologic changesMultifocal hepatic necrosisLater time pointsAcute necrotizingAcute peritonitisAcute phaseInflammatory lesionsImmunocompetent miceChronic infectionHepatic necrosisMHV infectionPathologic changes
2002
Assessment of static isolator cages with automatic watering when used with conventional husbandry techniques as a factor in the transmission of mouse hepatitis virus.
Macy JD, Cameron GA, Ellis SL, Hill EA, Compton SR. Assessment of static isolator cages with automatic watering when used with conventional husbandry techniques as a factor in the transmission of mouse hepatitis virus. Journal Of The American Association For Laboratory Animal Science 2002, 41: 30-5. PMID: 12109894.Peer-Reviewed Original ResearchMeSH KeywordsAnimal HusbandryAnimalsCoronavirus InfectionsDisease OutbreaksFecesFemaleHepatitis, Viral, AnimalHousing, AnimalMaleMiceMice, Inbred StrainsMurine hepatitis virusReverse Transcriptase Polymerase Chain ReactionRNA, ViralSpecific Pathogen-Free OrganismsWater SupplyConceptsFilter-top cagesMouse hepatitis virusUninoculated miceHepatitis virusCages of miceTransmission of infectionExamination of fecesLong-term useImmunocompetent miceHigh virus concentrationsPolymerase chain reaction amplificationMiceChain reaction amplificationWeeksStandard cagesMHV-A59Fecal samplesRoutine husbandrySerologyTest cageVirusInfected cagesInfectionReaction amplificationRows of cages