Genome-wide methylome-based molecular pathologies associated with depression and suicide
Dwivedi Y, Roy B, Korla P. Genome-wide methylome-based molecular pathologies associated with depression and suicide. Neuropsychopharmacology 2024, 1-12. PMID: 39645539, DOI: 10.1038/s41386-024-02040-9.Peer-Reviewed Original ResearchMajor depressive disorderMajor depressive disorder patientsMDD-SMajor depressive disorder groupsMethylation sitesDepressed non-suicidesDorsolateral prefrontal cortexAssociated with depressionDNA methylationMDD subjectsNonpsychiatric controlsDepressive disorderDepressed suicidesDepressed subjectsNon-suicidalSuicidal behaviorSuicide attemptsGenome-wide DNA methylationCompleted suicidePatterns of DNA methylationSuicidal thoughtsRegions of genesDNA methylation changesSuicideGenomic distribution