Publications
2023
- Altered Integrin Signaling in Thoracic Aortopathy.Humphrey JD, Schwartz MA. Arterioscler Thromb Vasc Biol. 2023 May 11; 2023 May 11. PMID: 37165879.
- FN (Fibronectin)-Integrin α5 Signaling Promotes Thoracic Aortic Aneurysm in a Mouse Model of Marfan Syndrome.Chen M, Cavinato C, Hansen J, Tanaka K, Ren P, Hassab A, Li DS, Youshao E, Tellides G, Iyengar R, Humphrey JD, Schwartz MA. Arterioscler Thromb Vasc Biol. 2023 May; 2023 Mar 30. PMID: 36994727.
- TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity.Gallego-Paez LM, Edwards WJS, Chanduri M, Guo Y, Koorman T, Lee CY, Grexa N, Derksen P, Yan J, Schwartz MA, Mauer J, Goult BT. J Cell Biol. 2023 May 1; 2023 Mar 6. PMID: 36880935.
- Dynamic antagonism between key repressive pathways maintains the placental epigenome.Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, Brändl B, Meierhofer D, Lupiáñez DG, Müller FJ, Aktas T, Elsässer SJ, Kretzmer H, Smith ZD, Meissner A. Nat Cell Biol. 2023 Apr; 2023 Apr 6. PMID: 37024684.
- Severely Reduced Kidney Function Assessed by a Single eGFR Determination at the Time of an Isolated Heart Transplant Does Not Predict Inevitable Posttransplant ESKD.Kumar A, Bonnell LN, Thomas CP. Transplantation. 2023 Apr 1; 2022 Oct 14. PMID: 36223634.
- Integrin α(IIb)β(3) intermediates: From molecular dynamics to adhesion assembly.Tong D, Soley N, Kolasangiani R, Schwartz MA, Bidone TC. Biophys J. 2023 Feb 7; 2022 Dec 23. PMID: 36566352.
2022
- Endothelial mechanosensing: A forgotten target to treat vascular remodeling in hypertension?Tiezzi M, Deng H, Baeyens N. Biochem Pharmacol. 2022 Dec; 2022 Oct 12. PMID: 36241094.
- Integrin Conformational Dynamics and Mechanotransduction.Kolasangiani R, Bidone TC, Schwartz MA. Cells. 2022 Nov 12; 2022 Nov 12. PMID: 36429013.
- The Transplant Kidney Biopsy: In Whose Hands?Virmani S, Kumar A. Kidney360. 2022 Oct 27; 2022 Oct 27. PMID: 36514728.
- The U-shaped association of post-lung transplant mortality with pretransplant eGFR underscores possible limitations of creatinine-based estimation equations for risk stratification.Kumar A, Bonnell LN, Eberlein M, Thomas CP. J Heart Lung Transplant. 2022 Sep; 2022 Jun 4. PMID: 35778259.
- Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes.Chen M, Hu R, Cavinato C, Zhuang ZW, Zhang J, Yun S, Fernandez Tussy P, Singh A, Murtada SI, Tanaka K, Liu M, Fernández-Hernando C, Humphrey JD, Schwartz MA. Diabetes. 2022 Sep 1. PMID: 35771994.
- The UIP/IPF fibroblastic focus is a collagen biosynthesis factory embedded in a distinct extracellular matrix.Herrera JA, Dingle L, Montero MA, Venkateswaran RV, Blaikley JF, Lawless C, Schwartz MA. JCI Insight. 2022 Aug 22; 2022 Aug 22. PMID: 35852874.
- MicroRNAs in Mechanical Homeostasis.Herrera JA, Schwartz MA. Cold Spring Harb Perspect Med. 2022 Aug 15; 2022 Aug 15. PMID: 35379658.
- High Fluid Shear Stress Inhibits Cytokine-Driven Smad2/3 Activation in Vascular Endothelial Cells.Deng H, Schwartz MA. J Am Heart Assoc. 2022 Jul 19; 2022 Jul 15. PMID: 35861829.
- A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells.Coon BG, Timalsina S, Astone M, Zhuang ZW, Fang J, Han J, Themen J, Chung M, Yang-Klingler YJ, Jain M, Hirschi KK, Yamamato A, Trudeau LE, Santoro M, Schwartz MA. J Cell Biol. 2022 Jul 4; 2022 Jun 13. PMID: 35695893.
- The evolution of performing a kidney biopsy: a single center experience comparing native and transplant kidney biopsies performed by interventional radiologists and nephrologists.Emelianova D, Prikis M, Morris CS, Gibson PC, Solomon R, Scriver G, Smith ZT, Bhave A, Shields J, DeSarno M, Kumar A. BMC Nephrol. 2022 Jun 25; 2022 Jun 25. PMID: 35752759.
- mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice.He C, Jiang B, Wang M, Ren P, Murtada SI, Caulk AW, Li G, Qin L, Assi R, Lovoulos CJ, Schwartz MA, Humphrey JD, Tellides G. JCI Insight. 2022 Feb 8; 2022 Feb 8. PMID: 35132962.
2021
- MEKK3-TGFβ crosstalk regulates inward arterial remodeling.Deng H, Xu Y, Hu X, Zhuang ZW, Chang Y, Wang Y, Ntokou A, Schwartz MA, Su B, Simons M. Proc Natl Acad Sci U S A. 2021 Dec 21. PMID: 34911761.
- Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta.Cavinato C, Chen M, Weiss D, Ruiz-Rodríguez MJ, Schwartz MA, Humphrey JD. Front Cardiovasc Med. 2021; 2021 Dec 16. PMID: 34977201.
- Integrin-based mechanosensing through conformational deformation.Driscoll TP, Bidone TC, Ahn SJ, Yu A, Groisman A, Voth GA, Schwartz MA. Biophys J. 2021 Oct 19; 2021 Sep 10. PMID: 34509509.
- Talin in mechanotransduction and mechanomemory at a glance.Goult BT, Brown NH, Schwartz MA. J Cell Sci. 2021 Oct 15; 2021 Oct 28. PMID: 34708856.
- Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction.Abou Ziki MD, Bhat N, Neogi A, Driscoll TP, Ugwu N, Liu Y, Smith E, Abboud JM, Chouairi S, Schwartz MA, Akar JG, Mani A. Hum Mutat. 2021 Oct; 2021 Jul 29. PMID: 34289528.
- Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling.Deng H, Min E, Baeyens N, Coon BG, Hu R, Zhuang ZW, Chen M, Huang B, Afolabi T, Zarkada G, Acheampong A, McEntee K, Eichmann A, Liu F, Su B, Simons M, Schwartz MA. Proc Natl Acad Sci U S A. 2021 Sep 14. PMID: 34504019.
- Fibronectin-Mediated Inflammatory Signaling Through Integrin α5 in Vascular Remodeling.Budatha M, Zhang J, Schwartz MA. J Am Heart Assoc. 2021 Sep 7; 2021 Sep 2. PMID: 34472370.
- Defective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia.Park H, Furtado J, Poulet M, Chung M, Yun S, Lee S, Sessa WC, Franco CA, Schwartz MA, Eichmann A. Circulation. 2021 Sep 7; 2021 Jun 29. PMID: 34182767.