Publications

Early Pre-Emptive Kidney Transplant Does Not Offer Any Mortality Benefits: A Study of Trends in Pre-Emptive Kidney Transplantation Over the Last Two Decades.Kumar A, Bonnell L, Kuppachi S. Transplant Proc. 2025 May; 2025 Mar 25. PMID: 40140312.
A Survey for Human Tissue-Level Determinants of CAV1 Regulation and Function.Jiménez-Jiménez V, Sánchez-Cabo F, Schwartz MA, Sánchez-Álvarez M, Del Pozo MÁ. Int J Mol Sci. 2025 Apr 17; 2025 Apr 17. PMID: 40332409.
Fluid Shear Stress-Regulated Vascular Remodeling: Past, Present, and Future.Deng H, Eichmann A, Schwartz MA. Arterioscler Thromb Vasc Biol. 2025 Apr 10; 2025 Apr 10. PMID: 40207366.
Pushing the Boundaries of Living Donation Through Kidney Paired Donation.Kumar A, Nishio Lucar AG, Doshi MD. Am J Kidney Dis. 2025 Apr; 2024 Dec 18. PMID: 39706246.
Short-term disruption of TGF-β signaling in adult mice renders the aorta vulnerable to hypertension-induced dissection.Jiang B, Ren P, He C, Wang M, Murtada SI, Ruiz-Rodríguez MJ, Chen Y, Ramachandra AB, Li G, Qin L, Assi R, Schwartz MA, Humphrey JD, Tellides G. JCI Insight. 2025 Feb 11; 2025 Feb 11. PMID: 39932797.
Conformational response of α(IIb)β(3) and α(V)β(3) integrins to force.Kolasangiani R, Farzanian K, Chen Y, Schwartz MA, Bidone TC. Structure. 2025 Feb 6; 2024 Dec 19. PMID: 39706199.
IGFBP6 contributes to vascular resilience.Schwartz MA. Nat Cardiovasc Res. 2025 Feb. PMID: 39794480.
Comparison of Safety and Efficacy of Aspiration Thrombectomy and Ultrasound Accelerated Thrombolysis for Management of Pulmonary Embolism: A Systematic Review and Meta-Analysis.Choksi EJ, Sare A, Shukla PA, Kumar A. Vasc Endovascular Surg. 2025 Feb; 2024 Oct 4. PMID: 39365670.
cSTAR analysis identifies endothelial cell cycle as a key regulator of flow-dependent artery remodeling.Deng H, Rukhlenko OS, Joshi D, Hu X, Junk P, Tuliakova A, Kholodenko BN, Schwartz MA. Sci Adv. 2025 Jan 3; 2025 Jan 3. PMID: 39752487.
DNA nanodevice for analysis of force-activated protein extension and interactions.Zhou K, Chung M, Cheng J, Powell JT, Yan Q, Liu J, Xiong Y, Schwartz MA, Lin C. bioRxiv. 2024 Dec 11; 2024 Dec 11. PMID: 39554144.
Polycomb Repressive Complex 2 promotes atherosclerotic plaque vulnerability.Joshi D, Chakraborty R, Bhogale T, Furtado J, Deng H, Traylor JG Jr, Orr AW, Martin KA, Schwartz MA. bioRxiv. 2024 Dec 2; 2024 Dec 2. PMID: 39703699.
Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation.Kumar A, Tanaka K, Schwartz MA. bioRxiv. 2024 Nov 14; 2024 Nov 14. PMID: 38045367.
Linear Free Energy Relationships Associated with Hydride Transfer From [(6,6'-R(2)-bpy)Re(CO)(3)H]: A Cautionary Tale in Identifying Hydrogen Bonding Effects in the Secondary Coordination Sphere.Elsby MR, Kumar A, Daniels LM, Ertem MZ, Hazari N, Mercado BQ, Paulus AH. Inorg Chem. 2024 Oct 14; 2024 Sep 30. PMID: 39344157.
DNA-Based Molecular Clamp for Probing Protein Interactions and Structure under Force.Chung M, Zhou K, Powell JT, Lin C, Schwartz MA. ACS Nano. 2024 Oct 8; 2024 Sep 29. PMID: 39344156.
Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis.Joshi D, Coon BG, Chakraborty R, Deng H, Yang Z, Babar MU, Fernandez-Tussy P, Meredith E, Attanasio J, Joshi N, Traylor JG Jr, Orr AW, Fernandez-Hernando C, Libreros S, Schwartz MA. Nat Cardiovasc Res. 2024 Sep; 2024 Sep 4. PMID: 39232138.
Controversy in mechanotransduction - the role of endothelial cell-cell junctions in fluid shear stress sensing.X S, Aitken C, Mehta V, Tardajos-Ayllon B, Serbanovic-Canic J, Zhu J, Miao B, Tzima E, Evans P, Fang Y, Schwartz MA. J Cell Sci. 2024 Sep 1; 2024 Sep 9. PMID: 39143856.
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis.Chanduri M, Kumar A, Weiss D, Emuna N, Barsukov I, Shi M, Tanaka K, Wang X, Datye A, Kanyo J, Collin F, Lam T, Schwarz UD, Bai S, Nottoli T, Goult BT, Humphrey JD, Schwartz MA. Sci Adv. 2024 Aug 23; 2024 Aug 21. PMID: 39167642.
Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions.Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, Hintzen J, Chung M, Kumar A, Mani A, Koleske A, Crawford J, Nicoli S, Schwartz MA. EMBO J. 2024 Aug; 2024 Jun 17. PMID: 38886581.
A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling.Deng H, Zhang J, Wang Y, Joshi D, Pi X, De Val S, Schwartz MA. Nat Cardiovasc Res. 2024 Jul; 2024 Jul 8. PMID: 39196179.
A DNA-based molecular clamp for probing protein interactions and structure under force.Chung M, Zhou K, Powell J, Lin C, Schwartz MA. bioRxiv. 2024 Jun 6; 2024 Jun 6. PMID: 38895381.
Integrins as Drug Targets in Vascular and Related Diseases.Meredith E, Schwartz MA. Int J Drug Discov Pharm. 2024 Jun; 2024 Jun 21. PMID: 39703402.
Afadin-nectin forces its way to the front.Sebbagh M, Schwartz MA. J Cell Biol. 2024 May 6; 2024 Apr 2. PMID: 38563860.
Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities.Stroope C, Nettersheim FS, Coon B, Finney AC, Schwartz MA, Ley K, Rom O, Yurdagul A Jr. Nat Metab. 2024 Apr; 2024 Mar 26. PMID: 38532071.
Calcium flow at ER-TGN contact sites facilitates secretory cargo export.Ramazanov BR, Parchure A, Di Martino R, Kumar A, Chung M, Kim Y, Griesbeck O, Schwartz MA, Luini A, von Blume J. Mol Biol Cell. 2024 Apr 1; 2024 Jan 31. PMID: 38294859.
Kidney after Liver Transplantation for All: Are You Kidneying Me?Kumar A, Wadei HM. Clin J Am Soc Nephrol. 2024 Mar 1; 2024 Jan 24. PMID: 38265809.
A large-scale retrospective study enabled deep-learning based pathological assessment of frozen procurement kidney biopsies to predict graft loss and guide organ utilization.Yi Z, Xi C, Menon MC, Cravedi P, Tedla F, Soto A, Sun Z, Liu K, Zhang J, Wei C, Chen M, Wang W, Veremis B, Garcia-Barros M, Kumar A, Haakinson D, Brody R, Azeloglu EU, Gallon L, O'Connell P, Naesens M, Shapiro R, Colvin RB, Ward S, Salem F, Zhang W. Kidney Int. 2024 Feb; 2023 Nov 3. PMID: 37923131.
Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis.Joshi D, Coon BG, Chakraborty R, Deng H, Fernandez-Tussy P, Meredith E, Traylor JG Jr, Orr AW, Fernandez-Hernando C, Schwartz MA. bioRxiv. 2024 Jan 21; 2024 Jan 21. PMID: 38293157.
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. J Clin Invest. 2024 Jan 4; 2024 Jan 4. PMID: 38175710.
Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton.Amiri S, Muresan C, Shang X, Huet-Calderwood C, Schwartz MA, Calderwood DA, Murrell M. Nat Commun. 2023 Dec 4; 2023 Dec 4. PMID: 38049429.
Report from the 2023 workshop on endothelial permeability, edema and inflammation.Vestweber D, Claesson-Welsh L, McDonald DM, Williams T, Schwartz MA, Scallan J, Gavins FNE, van Buul J, Gamble J, Vadas M, Annex BH, Messe SR, Perretti M, André H, Ferrara N, Hla T, Nourshargh S, Simons M. Nat Cardiovasc Res. 2023 Dec. PMID: 39196154.
SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations.Banerjee K, Lin Y, Gahn J, Cordero J, Gupta P, Mohamed I, Graupera M, Dobreva G, Schwartz MA, Ola R. J Clin Invest. 2023 Sep 15; 2023 Sep 15. PMID: 37490341.
The importance of character development in scientific research.Schwartz MA, Yap AS. J Cell Sci. 2023 Jul 1; 2023 Jul 5. PMID: 37403645.
Altered Integrin Signaling in Thoracic Aortopathy.Humphrey JD, Schwartz MA. Arterioscler Thromb Vasc Biol. 2023 Jul; 2023 May 11. PMID: 37165879.
Mechanisms of endothelial flow sensing.Aitken C, Mehta V, Schwartz MA, Tzima E. Nat Cardiovasc Res. 2023 Jun; 2023 Jun 12. PMID: 39195881.
FN (Fibronectin)-Integrin α5 Signaling Promotes Thoracic Aortic Aneurysm in a Mouse Model of Marfan Syndrome.Chen M, Cavinato C, Hansen J, Tanaka K, Ren P, Hassab A, Li DS, Youshao E, Tellides G, Iyengar R, Humphrey JD, Schwartz MA. Arterioscler Thromb Vasc Biol. 2023 May; 2023 Mar 30. PMID: 36994727.
TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity.Gallego-Paez LM, Edwards WJS, Chanduri M, Guo Y, Koorman T, Lee CY, Grexa N, Derksen P, Yan J, Schwartz MA, Mauer J, Goult BT. J Cell Biol. 2023 May 1; 2023 Mar 6. PMID: 36880935.
Dynamic antagonism between key repressive pathways maintains the placental epigenome.Weigert R, Hetzel S, Bailly N, Haggerty C, Ilik IA, Yung PYK, Navarro C, Bolondi A, Kumar AS, Anania C, Brändl B, Meierhofer D, Lupiáñez DG, Müller FJ, Aktas T, Elsässer SJ, Kretzmer H, Smith ZD, Meissner A. Nat Cell Biol. 2023 Apr; 2023 Apr 6. PMID: 37024684.
Severely Reduced Kidney Function Assessed by a Single eGFR Determination at the Time of an Isolated Heart Transplant Does Not Predict Inevitable Posttransplant ESKD.Kumar A, Bonnell LN, Thomas CP. Transplantation. 2023 Apr 1; 2022 Oct 14. PMID: 36223634.
Integrin α(IIb)β(3) intermediates: From molecular dynamics to adhesion assembly.Tong D, Soley N, Kolasangiani R, Schwartz MA, Bidone TC. Biophys J. 2023 Feb 7; 2022 Dec 23. PMID: 36566352.
Endothelial mechanosensing: A forgotten target to treat vascular remodeling in hypertension?Tiezzi M, Deng H, Baeyens N. Biochem Pharmacol. 2022 Dec; 2022 Oct 12. PMID: 36241094.
Integrin Conformational Dynamics and Mechanotransduction.Kolasangiani R, Bidone TC, Schwartz MA. Cells. 2022 Nov 12; 2022 Nov 12. PMID: 36429013.
The Transplant Kidney Biopsy: In Whose Hands?Virmani S, Kumar A. Kidney360. 2022 Oct 27; 2022 Oct 27. PMID: 36514728.
The U-shaped association of post-lung transplant mortality with pretransplant eGFR underscores possible limitations of creatinine-based estimation equations for risk stratification.Kumar A, Bonnell LN, Eberlein M, Thomas CP. J Heart Lung Transplant. 2022 Sep; 2022 Jun 4. PMID: 35778259.
Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes.Chen M, Hu R, Cavinato C, Zhuang ZW, Zhang J, Yun S, Fernandez Tussy P, Singh A, Murtada SI, Tanaka K, Liu M, Fernández-Hernando C, Humphrey JD, Schwartz MA. Diabetes. 2022 Sep 1. PMID: 35771994.
The UIP/IPF fibroblastic focus is a collagen biosynthesis factory embedded in a distinct extracellular matrix.Herrera JA, Dingle L, Montero MA, Venkateswaran RV, Blaikley JF, Lawless C, Schwartz MA. JCI Insight. 2022 Aug 22; 2022 Aug 22. PMID: 35852874.
MicroRNAs in Mechanical Homeostasis.Herrera JA, Schwartz MA. Cold Spring Harb Perspect Med. 2022 Aug 15; 2022 Aug 15. PMID: 35379658.
High Fluid Shear Stress Inhibits Cytokine-Driven Smad2/3 Activation in Vascular Endothelial Cells.Deng H, Schwartz MA. J Am Heart Assoc. 2022 Jul 19; 2022 Jul 15. PMID: 35861829.
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells.Coon BG, Timalsina S, Astone M, Zhuang ZW, Fang J, Han J, Themen J, Chung M, Yang-Klingler YJ, Jain M, Hirschi KK, Yamamato A, Trudeau LE, Santoro M, Schwartz MA. J Cell Biol. 2022 Jul 4; 2022 Jun 13. PMID: 35695893.
The evolution of performing a kidney biopsy: a single center experience comparing native and transplant kidney biopsies performed by interventional radiologists and nephrologists.Emelianova D, Prikis M, Morris CS, Gibson PC, Solomon R, Scriver G, Smith ZT, Bhave A, Shields J, DeSarno M, Kumar A. BMC Nephrol. 2022 Jun 25; 2022 Jun 25. PMID: 35752759.
mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice.He C, Jiang B, Wang M, Ren P, Murtada SI, Caulk AW, Li G, Qin L, Assi R, Lovoulos CJ, Schwartz MA, Humphrey JD, Tellides G. JCI Insight. 2022 Feb 8; 2022 Feb 8. PMID: 35132962.
MEKK3-TGFβ crosstalk regulates inward arterial remodeling.Deng H, Xu Y, Hu X, Zhuang ZW, Chang Y, Wang Y, Ntokou A, Schwartz MA, Su B, Simons M. Proc Natl Acad Sci U S A. 2021 Dec 21. PMID: 34911761.
Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta.Cavinato C, Chen M, Weiss D, Ruiz-Rodríguez MJ, Schwartz MA, Humphrey JD. Front Cardiovasc Med. 2021; 2021 Dec 16. PMID: 34977201.
Integrin-based mechanosensing through conformational deformation.Driscoll TP, Bidone TC, Ahn SJ, Yu A, Groisman A, Voth GA, Schwartz MA. Biophys J. 2021 Oct 19; 2021 Sep 10. PMID: 34509509.
Talin in mechanotransduction and mechanomemory at a glance.Goult BT, Brown NH, Schwartz MA. J Cell Sci. 2021 Oct 15; 2021 Oct 28. PMID: 34708856.
Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction.Abou Ziki MD, Bhat N, Neogi A, Driscoll TP, Ugwu N, Liu Y, Smith E, Abboud JM, Chouairi S, Schwartz MA, Akar JG, Mani A. Hum Mutat. 2021 Oct; 2021 Jul 29. PMID: 34289528.
Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling.Deng H, Min E, Baeyens N, Coon BG, Hu R, Zhuang ZW, Chen M, Huang B, Afolabi T, Zarkada G, Acheampong A, McEntee K, Eichmann A, Liu F, Su B, Simons M, Schwartz MA. Proc Natl Acad Sci U S A. 2021 Sep 14. PMID: 34504019.
Fibronectin-Mediated Inflammatory Signaling Through Integrin α5 in Vascular Remodeling.Budatha M, Zhang J, Schwartz MA. J Am Heart Assoc. 2021 Sep 7; 2021 Sep 2. PMID: 34472370.
Defective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia.Park H, Furtado J, Poulet M, Chung M, Yun S, Lee S, Sessa WC, Franco CA, Schwartz MA, Eichmann A. Circulation. 2021 Sep 7; 2021 Jun 29. PMID: 34182767.
Vascular Mechanobiology: Homeostasis, Adaptation, and Disease.Humphrey JD, Schwartz MA. Annu Rev Biomed Eng. 2021 Jul 13. PMID: 34255994.
Altered endocytosis in cellular senescence.Shin EY, Soung NK, Schwartz MA, Kim EG. Ageing Res Rev. 2021 Jul; 2021 Mar 19. PMID: 33753287.
Developmental Perspectives on Arterial Fate Specification.Chen D, Schwartz MA, Simons M. Front Cell Dev Biol. 2021; 2021 Jun 25. PMID: 34249941.
Early events in endothelial flow sensing.Tanaka K, Joshi D, Timalsina S, Schwartz MA. Cytoskeleton (Hoboken). 2021 Jun; 2021 Feb 15. PMID: 33543538.
Developmental origins of mechanical homeostasis in the aorta.Murtada SI, Kawamura Y, Li G, Schwartz MA, Tellides G, Humphrey JD. Dev Dyn. 2021 May; 2021 Jan 4. PMID: 33341996.
Structural and developmental principles of neuropil assembly in C. elegans.Moyle MW, Barnes KM, Kuchroo M, Gonopolskiy A, Duncan LH, Sengupta T, Shao L, Guo M, Santella A, Christensen R, Kumar A, Wu Y, Moon KR, Wolf G, Krishnaswamy S, Bao Z, Shroff H, Mohler WA, Colón-Ramos DA. Nature. 2021 Mar; 2021 Feb 24. PMID: 33627875.
Actin flow-dependent and -independent force transmission through integrins.Driscoll TP, Ahn SJ, Huang B, Kumar A, Schwartz MA. Proc Natl Acad Sci U S A. 2020 Dec 22; 2020 Dec 1. PMID: 33262280.
Integrin-mediated adhesions in regulation of cellular senescence.Shin EY, Park JH, You ST, Lee CS, Won SY, Park JJ, Kim HB, Shim J, Soung NK, Lee OJ, Schwartz MA, Kim EG. Sci Adv. 2020 May; 2020 May 6. PMID: 32494696.
Endothelial-to-Mesenchymal Transition, Vascular Inflammation, and Atherosclerosis.Chen PY, Schwartz MA, Simons M. Front Cardiovasc Med. 2020; 2020 May 5. PMID: 32478094.
Author Correction: Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Cruz CSD, Palm NW, Jackson R, Flavell RA. Nature. 2019 Nov. PMID: 31712625.
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis.Chen PY, Qin L, Li G, Wang Z, Dahlman JE, Malagon-Lopez J, Gujja S, Cilfone NA, Kauffman KJ, Sun L, Sun H, Zhang X, Aryal B, Canfran-Duque A, Liu R, Kusters P, Sehgal A, Jiao Y, Anderson DG, Gulcher J, Fernandez-Hernando C, Lutgens E, Schwartz MA, Pober JS, Chittenden TW, Tellides G, Simons M. Nat Metab. 2019 Sep; 2019 Aug 26. PMID: 31572976.
Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Dela Cruz CS, Palm NW, Jackson R, Flavell RA. Nature. 2019 Sep; 2019 Aug 21. PMID: 31435009.
Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis.Yun S, Hu R, Schwaemmle ME, Scherer AN, Zhuang Z, Koleske AJ, Pallas DC, Schwartz MA. J Clin Invest. 2019 Aug 13; 2019 Aug 13. PMID: 31408443.
Filamin A mediates isotropic distribution of applied force across the actin network.Kumar A, Shutova MS, Tanaka K, Iwamoto DV, Calderwood DA, Svitkina TM, Schwartz MA. J Cell Biol. 2019 Aug 5; 2019 Jul 17. PMID: 31315944.
Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation.Ramírez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C. Circulation. 2019 Jul 16; 2019 Jun 3. PMID: 31154825.
Isotropic Light-Sheet Microscopy and Automated Cell Lineage Analyses to Catalogue Caenorhabditis elegans Embryogenesis with Subcellular Resolution.Duncan LH, Moyle MW, Shao L, Sengupta T, Ikegami R, Kumar A, Guo M, Christensen R, Santella A, Bao Z, Shroff H, Mohler W, Colón-Ramos DA. J Vis Exp. 2019 Jun 6; 2019 Jun 6. PMID: 31233035.
MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation.Hu X, Liu ZZ, Chen X, Schulz VP, Kumar A, Hartman AA, Weinstein J, Johnston JF, Rodriguez EC, Eastman AE, Cheng J, Min L, Zhong M, Carroll C, Gallagher PG, Lu J, Schwartz M, King MC, Krause DS, Guo S. Nat Commun. 2019 Apr 12; 2019 Apr 12. PMID: 30979898.
Coarse-Grained Simulation of Full-Length Integrin Activation.Bidone TC, Polley A, Jin J, Driscoll T, Iwamoto DV, Calderwood DA, Schwartz MA, Voth GA. Biophys J. 2019 Mar 19; 2019 Feb 22. PMID: 30851876.
Translocating transcription factors in fluid shear stress-mediated vascular remodeling and disease.Min E, Schwartz MA. Exp Cell Res. 2019 Mar 1; 2019 Jan 8. PMID: 30633880.
ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis.Lay AJ, Coleman PR, Formaz-Preston A, Ting KK, Roediger B, Weninger W, Schwartz MA, Vadas MA, Gamble JR. J Am Heart Assoc. 2019 Jan 22. PMID: 30630384.
Vinculin and the mechanical response of adherent fibroblasts to matrix deformation.Rosowski KA, Boltyanskiy R, Xiang Y, Van den Dries K, Schwartz MA, Dufresne ER. Sci Rep. 2018 Dec 19; 2018 Dec 19. PMID: 30568231.
Talin as a mechanosensitive signaling hub.Goult BT, Yan J, Schwartz MA. J Cell Biol. 2018 Nov 5; 2018 Sep 25. PMID: 30254032.
Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale.Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA. Biophys J. 2018 Oct 16; 2018 Sep 10. PMID: 30274833.
hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis.Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, Antoniani B, Sperduti I, Di Benedetto A, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen EI, Schwartz MA, Santoni A, Bissell MJ, Nisticò P. Oncogene. 2018 Oct; 2018 Jun 15. PMID: 29907768.
Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy.Liao X, Shen Y, Zhang R, Sugi K, Vasudevan NT, Alaiti MA, Sweet DR, Zhou L, Qing Y, Gerson SL, Fu C, Wynshaw-Boris A, Hu R, Schwartz MA, Fujioka H, Richardson B, Cameron MJ, Hayashi H, Stamler JS, Jain MK. Proc Natl Acad Sci U S A. 2018 May 15; 2018 Apr 30. PMID: 29712858.
A unifying concept in vascular health and disease.Schwartz MA, Vestweber D, Simons M. Science. 2018 Apr 20. PMID: 29674582.
Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK. Nat Commun. 2018 Feb 14; 2018 Feb 14. PMID: 29445140.
Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis.Budatha M, Zhang J, Zhuang ZW, Yun S, Dahlman JE, Anderson DG, Schwartz MA. J Am Heart Assoc. 2018 Jan 30; 2018 Jan 30. PMID: 29382667.
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK. Nat Commun. 2017 Dec 15; 2017 Dec 15. PMID: 29247167.
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish.Lagendijk AK, Gomez GA, Baek S, Hesselson D, Hughes WE, Paterson S, Conway DE, Belting HG, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM. Nat Commun. 2017 Nov 10; 2017 Nov 10. PMID: 29123087.
VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN.Conway DE, Coon BG, Budatha M, Arsenovic PT, Orsenigo F, Wessel F, Zhang J, Zhuang Z, Dejana E, Vestweber D, Schwartz MA. Curr Biol. 2017 Jul 24; 2017 Jul 14. PMID: 28712573.
Visualizing Calcium Flux in Freely Moving Nematode Embryos.Ardiel EL, Kumar A, Marbach J, Christensen R, Gupta R, Duncan W, Daniels JS, Stuurman N, Colón-Ramos D, Shroff H. Biophys J. 2017 May 9. PMID: 28494967.
Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M. Development. 2016 Dec 1; 2016 Oct 27. PMID: 27789626.
Dynamic interaction between actin and nesprin2 maintain the cell nucleus in a prestressed state.Kumar A, Shivashankar GV. Methods Appl Fluoresc. 2016 Nov 11; 2016 Nov 11. PMID: 28192301.
Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling.Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA. Nat Cell Biol. 2016 Oct; 2016 Sep 5. PMID: 27595237.
Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia.Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA. J Cell Biol. 2016 Sep 26; 2016 Sep 19. PMID: 27646277.
An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression.Ahmed M, Sottnik JL, Dancik GM, Sahu D, Hansel DE, Theodorescu D, Schwartz MA. Cancer Cell. 2016 Sep 12; 2016 Sep 1. PMID: 27593345.
Ion Channels in Endothelial Responses to Fluid Shear Stress.Gerhold KA, Schwartz MA. Physiology (Bethesda). 2016 Sep. PMID: 27511462.
Comparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine.Balestrini JL, Gard AL, Gerhold KA, Wilcox EC, Liu A, Schwan J, Le AV, Baevova P, Dimitrievska S, Zhao L, Sundaram S, Sun H, Rittié L, Dyal R, Broekelmann TJ, Mecham RP, Schwartz MA, Niklason LE, White ES. Biomaterials. 2016 Sep; 2016 Jun 16. PMID: 27344365.
Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.Pawar A, Meier JA, Dasgupta A, Diwanji N, Deshpande N, Saxena K, Buwa N, Inchanalkar S, Schwartz MA, Balasubramanian N. Cell Signal. 2016 Sep; 2016 Jun 4. PMID: 27269287.
Using Stage- and Slit-Scanning to Improve Contrast and Optical Sectioning in Dual-View Inverted Light Sheet Microscopy (diSPIM).Kumar A, Christensen R, Guo M, Chandris P, Duncan W, Wu Y, Santella A, Moyle M, Winter PW, Colón-Ramos D, Bao Z, Shroff H. Biol Bull. 2016 Aug. PMID: 27638693.
Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus.Li N, Subrahmanyan L, Smith E, Yu X, Zaidi S, Choi M, Mane S, Nelson-Williams C, Behjati M, Kazemi M, Hashemi M, Fathzadeh M, Narayanan A, Tian L, Montazeri F, Mani M, Begleiter ML, Coon BG, Lynch HT, Olson EN, Zhao H, Ruland J, Lifton RP, Mani A. Am J Hum Genet. 2016 Jun 2; 2016 May 12. PMID: 27181681.