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What started as a weeklong trip to treat pediatric epilepsy patients in Africa nearly 20 years ago has evolved into a sophisticated data collection and public health program that is providing Yale researchers with answers about the mysterious source of a neurological disease killing children.

The Center for Brain & Mind Health Pilot Program is the center's annual keystone initiative, embodying its core value of interdisciplinary collaboration as a driver of clinically relevant neuroscience.

Yale researchers linked low water availability before birth to Ugandan children who failed to reach normal growth.

In recent years, his work has fused his interests in physics and engineering with novel approaches to tackling global health problems in neurosurgery, such as work in Africa on hydrocephalus, neonatal sepsis, sustainable MRI imaging, childhood brain growth and image analysis, and satellite rainfall analysis.

On this Week in Microbiology (TWiM), Michelle Swanson and the TWiM team discuss [minute 32] the identification of a deadly bacterial strain causing widespread deaths of newborns in Uganda.

Thousands of babies in the central African country develop post-infectious hydrocephalus (PIH) every year, many of whom go on to die. In June, the Lancet Microbe published the results of research in Uganda. A bacteria (Paenibacillus thiaminolyticus) was identified as the predominant infection agent for both neonatal sepsis and the subsequent PIH that developed in new-born babies.

On June 19, 2023, after 16 years of persistent pursuit of answers, the team published a landmark paper in The Lancet Microbe detailing the results of three linked studies, conclusively identifying the Paenibacillus thiaminolyticus bacteria as responsible for postinfectious hydrocephalus in Uganda.