TMPRSS4: A Novel Tumor Prognostic Indicator for the Stratification of Stage IA Tumors and a Liquid Biopsy Biomarker for NSCLC Patients
Villalba M, Exposito F, Pajares MJ, Sainz C, Redrado M, Remirez A, Wistuba I, Behrens C, Jantus-Lewintre E, Camps C, Montuenga LM, Pio R, Lozano MD, de Andrea C, Calvo A. TMPRSS4: A Novel Tumor Prognostic Indicator for the Stratification of Stage IA Tumors and a Liquid Biopsy Biomarker for NSCLC Patients. Journal Of Clinical Medicine 2019, 8: 2134. PMID: 31817025, PMCID: PMC6947244, DOI: 10.3390/jcm8122134.Peer-Reviewed Original ResearchTMPRSS4 protein expressionNSCLC patientsHigh riskEighth TNM staging systemCell lung cancer patientsEarly-stage NSCLC patientsEighth TNM classificationOverall survival HRRelapse/deathStage IA tumorsProtein expressionIndependent prognostic factorYear of diagnosisTNM staging systemStage NSCLC patientsLung cancer patientsBronchoalveolar lavage samplesCase-control studyNon-invasive biomarkersLiquid biopsy biomarkersIA tumorsStage IAPrognostic factorsRelapse rateTNM classification