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Lung Cancer: How Tumors Develop, Resist Treatment, and What Comes Next

Why do some lung cancers stop responding to drugs that once worked? And why does the immune system sometimes fail to recognize and destroy tumors? Pathologist Katerina Politi, PhD, has spent more than two decades pursuing those questions, and her team at Yale School of Medicine is now closer to finding answers that could reshape how patients are treated.

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  • Progress and Hope: Sharing the Latest Advances in Lung Cancer Care

    On November 17, 2025, in honor of Lung Cancer Awareness Month, members of our Center for Thoracic Cancers at Smilow Cancer Hospital and Yale Cancer Center presented a patient forum: "Progress and Hope: Sharing the Latest Advances in Lung Cancer Care." The event was held in person at 55 Park Street in New Haven, CT.

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  • Yale’s Lung Cancer SPORE Grant Renewed by National Cancer Institute

    Yale Cancer Center's Specialized Program of Research Excellence (SPORE) in Lung Cancer has been awarded a renewal grant from the National Cancer Institute (NCI) for year 11 of the program. The prestigious grant, totaling $12M over five years, will provide critical funding to advance groundbreaking lung cancer research and accelerate progress in the prevention, detection, and treatment of this disease.

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  • Yale Cancer Center Advocates for Research Funding on "Hill Day"

    Yale Cancer Center joined Hill Day, hosted by the American Association for Cancer Research (AACR) and the Association of American Cancer Institutes (AACI) to bring cancer center directors, researchers, physician-scientists, cancer survivors, and other advocates together to build support for a strong federal investment in biomedical research—and cancer research in particular—through the National Institutes of Health (NIH) and the National Cancer Institute (NCI). Hill Day is a special opportunity in that it helps members of cancer centers secure time to meet with their Congressional representatives to share the importance and impact of cancer funding.

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  • New Research Presented from Yale Cancer Center at #AACR25

    Yale Cancer Center faculty and trainees joined 22,000 cancer researchers from around the world to share the latest advances in cancer science and medicine earlier this week in Chicago for the 116th American Association for Cancer Research (AACR) annual meeting. Dr. Patricia LoRusso, Amy and Joseph Perella Professor of Medicine at Yale Cancer Center and AACR President for 2024-25, shared her global view on cancer. “Cancer is a global disease—it spares no continent, no country. And each patient that gets the disease deserves treatment.”

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