2019
Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes
Groman SM, Keistler C, Keip AJ, Hammarlund E, DiLeone RJ, Pittenger C, Lee D, Taylor JR. Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes. Neuron 2019, 103: 734-746.e3. PMID: 31253468, PMCID: PMC6893860, DOI: 10.1016/j.neuron.2019.05.042.Peer-Reviewed Original Research
2014
In the Blink of an Eye: Relating Positive-Feedback Sensitivity to Striatal Dopamine D2-Like Receptors through Blink Rate
Groman SM, James AS, Seu E, Tran S, Clark TA, Harpster SN, Crawford M, Burtner JL, Feiler K, Roth RH, Elsworth JD, London ED, Jentsch JD. In the Blink of an Eye: Relating Positive-Feedback Sensitivity to Striatal Dopamine D2-Like Receptors through Blink Rate. Journal Of Neuroscience 2014, 34: 14443-14454. PMID: 25339755, PMCID: PMC4205561, DOI: 10.1523/jneurosci.3037-14.2014.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlinkingChlorocebus aethiopsCorpus StriatumDiscrimination LearningFeedback, PhysiologicalMalePhotic StimulationReceptors, Dopamine D2Time FactorsConceptsDopamine D2-like receptorsD2-like receptorsPositron emission tomographyStriatal dopamine D2-like receptorsPositive feedback sensitivityAdult male vervet monkeysDopamine D2 receptorsD2-like receptor availabilityDopaminergic transmissionPharmacological assessmentD2 receptorsMale vervet monkeysReceptor numberReceptor availabilityEmission tomographyBlink rateReceptorsSimple behavioral measurePET measurementsHuman brainReversal-learning performanceVervet monkeysBehavioral measuresHuman impulsivityBehavioral addictions