2020
The Neurobiology of Impulsive Decision-Making and Reinforcement Learning in Nonhuman Animals
Groman SM. The Neurobiology of Impulsive Decision-Making and Reinforcement Learning in Nonhuman Animals. Current Topics In Behavioral Neurosciences 2020, 47: 23-52. PMID: 32157666, DOI: 10.1007/7854_2020_127.Peer-Reviewed Original ResearchConceptsImpulsive choiceNonhuman animalsReinforcement learning processSophisticated behavioralImpulsive decisionNeural mechanismsNeuroscience techniquesNeurobiological mechanismsNeuromodulatory systemsBehavioral heterogeneityApplication of reinforcementLearning processNeurochemical basisMental illnessIntegration of reinforcementImpulsivityPathological levels
2017
Chronic Exposure to Methamphetamine Disrupts Reinforcement-Based Decision Making in Rats
Groman SM, Rich KM, Smith NJ, Lee D, Taylor JR. Chronic Exposure to Methamphetamine Disrupts Reinforcement-Based Decision Making in Rats. Neuropsychopharmacology 2017, 43: 770-780. PMID: 28741627, PMCID: PMC5809784, DOI: 10.1038/npp.2017.159.Peer-Reviewed Original ResearchConceptsReinforcement learning processAbility of ratsNegative outcomesAdaptive decision-making strategiesProbabilistic reversal learningStimulus-reward contingenciesDopamine D2/3 receptor antagonistDynamic decision makingMaladaptive decisionReversal learningDecision-making strategiesD2/3 receptor antagonistOutcome behaviorsPsychostimulant methamphetamineChronic exposurePsychostimulant addictionChoice behaviorBehavioral mechanismsComputational modelDetrimental outcomesPsychostimulant drugsCurrent studyDecision makingDecision-making processDrug use