2009
Neuronal Correlates of Instrumental Learning in the Dorsal Striatum
Kimchi EY, Torregrossa MM, Taylor JR, Laubach M. Neuronal Correlates of Instrumental Learning in the Dorsal Striatum. Journal Of Neurophysiology 2009, 102: 475-489. PMID: 19439679, PMCID: PMC2712266, DOI: 10.1152/jn.00262.2009.Peer-Reviewed Original ResearchConceptsDorsal striatumResponse portsNeuronal activityTask-related firingTask-related neuronsMovement-related potentialsInitiation of movementLateral striatumLearning-related changesMedial striatumStriatumNeuronal correlatesReward portNumber of neuronsAcoustic stimuliNeuronsOperant taskField potentialsProgressive increaseLateral regionsTheta-band oscillationsHigh rateTraining periodInstrumental learningHead entries
1989
Limbic-striatal interactions in reward-related processes
Robbins T, Cador M, Taylor J, Everitt B. Limbic-striatal interactions in reward-related processes. Neuroscience & Biobehavioral Reviews 1989, 13: 155-162. PMID: 2682402, DOI: 10.1016/s0149-7634(89)80025-9.Peer-Reviewed Original ResearchConceptsVentral striatumDA depletionIndirect dopamine agonist d-amphetamineStriatal DA depletionReward-related stimuliAgonist d-amphetamineSelective stimulatory effectDA-dependent processesBasolateral nucleusD-amphetamineExcitotoxic lesionsReward-related processesSecond-order scheduleDorsal striatumStriatumAmygdala lesionsStimulatory effectLesionsSimilar discriminative propertiesDiscriminative propertiesOrder schedulePredictive associationsSexual reinforcementDorsalParallel findingsSymptomatic and asymptomatic 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridinetreated primates: Biochemical changes in striatal regions
Elsworth J, Deutch A, Redmond D, Taylor J, Sladek J, Roth R. Symptomatic and asymptomatic 1 -methyl-4-phenyl-1,2,3,6-tetrahydropyridinetreated primates: Biochemical changes in striatal regions. Neuroscience 1989, 33: 323-331. PMID: 2622529, DOI: 10.1016/0306-4522(89)90212-1.Peer-Reviewed Original ResearchConceptsHomovanillic acid concentrationsParkinson's diseaseStriatal regionsHomovanillic acid/dopamine ratioGross motor abnormalitiesDepletion of dopamineHomovanillic acid levelsLoss of dopamineIdiopathic Parkinson's diseaseCaudate nucleus dopamineAsymptomatic monkeysTetrahydropyridine (MPTP) treatmentAsymptomatic groupSymptomatic groupDopamine lossTetrahydropyridine (MPTP) toxicityMotor abnormalitiesDopamine ratioCaudate nucleusSignificant negative correlationVentromedial regionStriatum