1999
Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitization
Taylor J, Horger B. Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitization. Psychopharmacology 1999, 142: 31-40. PMID: 10102780, DOI: 10.1007/s002130050859.Peer-Reviewed Original ResearchConceptsIntra-accumbens amphetamineIntra-NAc amphetamineCocaine sensitizationLocomotor sensitizationNucleus accumbensCR leverLong-term neuronal adaptationsSaline-treated groupMesolimbic dopamine systemStimulant drug useSaline infusionSaline injectionDopamine systemPsychomotor stimulantsDrug useNeuronal adaptationConditioned rewardStimulant drugsAmphetaminePrior exposureSensitizationTest daySeparate groupsNCR leverPredictive associations
1991
Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens
Cador M, Taylor J, Robbins T. Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens. Psychopharmacology 1991, 104: 377-385. PMID: 1924645, DOI: 10.1007/bf02246039.Peer-Reviewed Original ResearchConceptsDorsal noradrenergic bundleDose-dependent increaseDA-dependent mechanismSignificant dose-dependent increaseSmaller infusion volumesDA infusionDA receptorsAlpha-flupenthixolNoradrenergic bundleSystemic doseProfound depletionNucleus accumbensReward-related processesInfusion volumeNeurotoxic lesionsNA levelsNeurochemical mediationNoradrenalinePotentiationCONDITIONED REINFORCEMENTDopamineReward-related stimuliConditioned reinforcersAmphetamineDoses