Lighting a new path to understanding the 'language' of the brain
School of Medicine researchers have developed a new technique that allows them to non-invasively and simultaneously measure electrical activity in many neurons in a living organism, a prerequisite for understanding the complex language of the brain. The technique, described in the Aug. 8 issue of the journal Cell, involves inserting a fluorescent protein that varies in intensity in response to changes in electrical signals into neurons and recording the changing light with optical sensors.
Discovering the 'Cytokine Language' That Activates Immune Responses
Using a new computational method based on a causal inference framework, CINEMA-OT, the Yale team studied how individual immune cells react to combinations of cytokines, or small proteins released by cells that regulate inflammation. They discovered that certain cytokines have a synergistic effect, inducing unique gene activation programs compared to their individual effects. This cryptography of cytokine signals acts as a language, instructing immune cells.
Accepting Applications for Extramural Postdoc Seminar Series SYNAPSES 2023/2024
SYNAPSES (Seminars at Yale Neuroscience: Advanced PoStdoc Extramural Series) brings to Yale postdocs from around the world to share their latest work. Applications for the 2023-2024 SYNAPSES seminars will be accepted until 11:59pm on September 5, 2023.
Guo receives 2023 Neurobiology of Brain Disorders Awards from the McKnight Foundation
The McKnight Endowment Fund for Neuroscience has selected Junjie Guo, PhD, from Yale Neuroscience, to receive the 2023 Neurobiology of Brain Disorders Awards. This award supports innovative research by U.S. scientists who are studying the biological mechanisms of neurological and psychiatric disorder.Source: McKnight Foundation
High-speed low-light in vivo two-photon voltage imaging of large neuronal populations
In a new Nature Methods paper, Jelena Platisa, PhD (YSM and The John B. Pierce Laboratory) and collaborators combined approaches to increase the capacity for high-speed deep-tissue imaging in awake behaving animal.Source: Nature Methods
14th Annual Brain Education Day: “They start to see graduate students more as neighbors”
On Mar. 12, Brain Education Day returned in-person for the first time since 2019. The annual outreach program exposes local middle and high school students to neuroscience. Co-sponsored by Yale Pathways to Science and the Office for Graduate Student Development and Diversity (OGSDD), the event is open to Pathways students in grades 6 to 12. Due to COVID-19 restrictions, previous years’ events were held virtually.
#TraineeTuesday: David Andrijevic, MD
Meet David Andrijevic, MD, an associate research scientist in the Sestan lab! Andrijevic’s work reviving cell function in deceased pigs made national headlines, including recognition by National Geographic as one of the most amazing discoveries of 2022. Let’s explore his research journey and where he hopes it takes him.
Patricia Goldman-Rakic, PhD, celebrated among 10 women medical pioneers
These inspiring women endured poverty, deep-seated stereotypes, and discrimination, but they went on to build hospitals, win a Nobel Prize, lead a medical school, and dramatically improve the health of millions. Read their incredible stories.Source: AAMC
Enock Teefe and José Jaime Martínez-Magaña Receive 2023 Kavli Postdoctoral Award for Academic Diversity
Enock Teefe, MD, from the laboratory of Thomas Fernandez, MD, and co-mentored by Christopher Pittenger, MD, PhD, and José Jaime Martínez-Magaña, PhD, from the laboratory of Janitza Montalvo-Ortiz, PhD, have been selected to receive the 2023 Kavli Postdoctoral Award for Academic Diversity.
In Memoriam: Gordon Murray Shepherd, MD, DPhil
We write today to share that Gordon Murray Shepherd, MD, DPhil, professor emeritus in the Department of Neuroscience, passed away on June 9, 2022. His leadership extended from research to education, and was infused with personal integrity, generosity, and great wisdom. The obituary below was prepared by Stephen Strittmatter, MD, PhD.
DPAG launches “Body, Brain, Behavior: Three Views and a Conversation” in Oxford
The Oxford Book Launch 'Body Brain Behavior - The Need For Conversations' brought together three world leading scientist authors, Professor Zoltán Molnár and Yale Professors Tamas Horvath and Joy Hirsch, with Oxford's neuroscience community on Thursday 7 April 2022.Source: University of Oxford Department of Physiology, Anatomy and Genetics (DPAG)
LaShae Nicholson and Rafael Perez Receive Kavli Postdoctoral Award for Academic Diversity
LaShae Nicholson, PhD, from the laboratory of Stephen Strittmatter, and Rafael Perez, PhD, from the laboratory of Marina Picciotto, have been selected to receive the Kavli Postdoctoral Award for Academic Diversity.