- July 06, 2023
NeuroEXPLORER Images Unveiled at SNMMI
- November 20, 2019
Yale Researchers Measure Ketamine's Effects on a Glutamate Receptor
- April 04, 2019Source: Nature Communications
Lower synaptic density is associated with depression severity and network alterations
- September 04, 2018
Eight Yale affiliates awarded NARSAD Young Investigator Grants
- July 17, 2018Source: Chronic Stress
Cerebellar and prefrontal cortical alterations in PTSD: Structural and functional evidence
- July 22, 2016Source: ALZFORUM
Next Up for Human Brain Imaging: Synaptic Density?
Recent Publications
2024
- Does seasonal variation affect the neuroimmune system? A retrospective [(11)C]PBR28 PET study in healthy individuals.Ibrahim W, An J, Yang Y, Cosgrove KP, Matuskey D. Neurosci Lett. 2024 Apr 1; 2024 Apr 5. PMID: 38583505.
- Author Correction: Synaptic loss and its association with symptom severity in Parkinson's disease.Holmes SE, Honhar P, Tinaz S, Naganawa M, Hilmer AT, Gallezot JD, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis ED, Comley R, Finnema SJ, Carson RE, Matuskey D. NPJ Parkinsons Dis. 2024 Mar 12; 2024 Mar 12. PMID: 38472206.
- Imaging a putative marker of brain cortisol regulation in alcohol use disorder.Verplaetse TL, Hillmer AT, Bhatt S, Rusowicz A, Li S, Nabulsi N, Matuskey D, Huang Y, McKee SA, Cosgrove KP. Neurobiol Stress. 2024 Mar; 2024 Jan 21. PMID: 38304303.
- The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [(11)C]UCB-J.Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Eur J Nucl Med Mol Imaging. 2024 Mar; 2023 Nov 13. PMID: 37955791.
- Synaptic loss and its association with symptom severity in Parkinson's disease.Holmes SE, Honhar P, Tinaz S, Naganawa M, Hilmer AT, Gallezot JD, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis ED, Comley R, Finnema SJ, Carson RE, Matuskey D. NPJ Parkinsons Dis. 2024 Feb 24; 2024 Feb 24. PMID: 38402233.
- First-in-Human Study of (18)F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding.Drake LR, Wu Y, Naganawa M, Asch R, Zheng C, Najafzadeh S, Pracitto R, Lindemann M, Li S, Ropchan J, Labaree D, Emery PR, Dias M, Henry S, Nabulsi N, Matuskey D, Hillmer AT, Gallezot JD, Carson RE, Cai Z, Huang Y. J Nucl Med. 2024 Feb 15; 2024 Feb 15. PMID: 38360052.
- The Relationship of Cerebrospinal Fluid Biomarkers and Cognitive Performance in Frontotemporal Dementia.Cayir S, Sadabad FE, Mecca A, Matuskey D, Zadeh AF. Res Sq. 2024 Feb 13; 2024 Feb 13. PMID: 38410483.
- Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson's disease.de Laat B, Hoye J, Stanley G, Hespeler M, Ligi J, Mohan V, Wooten DW, Zhang X, Nguyen TD, Key J, Colonna G, Huang Y, Nabulsi N, Patel A, Matuskey D, Morris ED, Tinaz S. NPJ Parkinsons Dis. 2024 Feb 9; 2024 Feb 9. PMID: 38336768.
- Improving SUVR quantification by correcting for radiotracer clearance in tissue.Honhar P, Matuskey D, Carson RE, Hillmer AT. J Cereb Blood Flow Metab. 2024 Feb; 2023 Aug 17. PMID: 37589538.
- Relationship between Neuroimaging and Cognition in Frontotemporal Dementia: A [18 F]FDG PET and Structural MRI Study.Cayir S, Volpi T, Toyonaga T, Gallezot JD, Yanghong Y, Sadabad FE, Mulnix T, Mecca AP, Fesharaki-Zadeh A, Matuskey D. Res Sq. 2024 Jan 15; 2024 Jan 15. PMID: 38313264.
2023
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Cerebellum. 2023 Oct 3; 2023 Oct 3. PMID: 37783917.
- Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender.Koohsari S, Sadabad FE, Pittman B, Gallezot JD, Carson RE, van Dyck CH, Li CR, Potenza MN, Matuskey D. Synapse. 2023 Sep; 2023 Jun 29. PMID: 37382240.
- Imaging the brain's immune response to alcohol with [(11)C]PBR28 TSPO Positron Emission Tomography.Raval NR, Angarita G, Matuskey D, Miller R, Drake LR, Kapinos M, Nabulsi N, Huang Y, Carson RE, O'Malley SS, Cosgrove KP, Hillmer AT. Mol Psychiatry. 2023 Aug; 2023 Aug 2. PMID: 37532797.
- A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression.Jauhar S, Arnone D, Baldwin DS, Bloomfield M, Browning M, Cleare AJ, Corlett P, Deakin JFW, Erritzoe D, Fu C, Fusar-Poli P, Goodwin GM, Hayes J, Howard R, Howes OD, Juruena MF, Lam RW, Lawrie SM, McAllister-Williams H, Marwaha S, Matuskey D, McCutcheon RA, Nutt DJ, Pariante C, Pillinger T, Radhakrishnan R, Rucker J, Selvaraj S, Stokes P, Upthegrove R, Yalin N, Yatham L, Young AH, Zahn R, Cowen PJ. Mol Psychiatry. 2023 Aug; 2023 Jun 16. PMID: 37322065.
- Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder.Holmes SE, Asch RH, Davis MT, DellaGioia N, Pashankar N, Gallezot JD, Nabulsi N, Matuskey D, Sanacora G, Carson RE, Blumberg HP, Esterlis I. Biol Psychiatry. 2023 Jun 15; 2022 Nov 8. PMID: 36764853.
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Res Sq. 2023 May 2; 2023 May 2. PMID: 37205584.
- Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[(18)F]flubatine PET study.Calakos KC, Hillmer AT, Anderson JM, LeVasseur B, Baldassarri SR, Angarita GA, Matuskey D, Kapinos M, Zheng MQ, Huang Y, Cosgrove KP. Neuropsychopharmacology. 2023 Mar; 2023 Jan 21. PMID: 36681758.
- Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.Matuskey D, Gallezot JD, Nabulsi N, Henry S, Torres K, Dias M, Angarita GA, Huang Y, Shoaf SE, Carson RE, Mehrotra S. J Psychopharmacol. 2023 Feb; 2022 Dec 14. PMID: 36515395.
- D3 Receptors and PET Imaging.Koohsari S, Yang Y, Matuskey D. Curr Top Behav Neurosci. 2023. PMID: 35711027.
2022
- Age, gender and body-mass-index relationships with in vivo CB(1) receptor availability in healthy humans measured with [(11)C]OMAR PET.Radhakrishnan R, Worhunsky PD, Zheng MQ, Najafzadeh S, Gallezot JD, Planeta B, Henry S, Nabulsi N, Ranganathan M, Skosnik PD, Pittman B, Cyril D'Souza D, Carson RE, Huang Y, Potenza MN, Matuskey D. Neuroimage. 2022 Dec 1; 2022 Oct 13. PMID: 36243269.