- July 06, 2023
NeuroEXPLORER Images Unveiled at SNMMI
- November 20, 2019
Yale Researchers Measure Ketamine's Effects on a Glutamate Receptor
- April 04, 2019Source: Nature Communications
Lower synaptic density is associated with depression severity and network alterations
- September 04, 2018
Eight Yale affiliates awarded NARSAD Young Investigator Grants
- July 17, 2018Source: Chronic Stress
Cerebellar and prefrontal cortical alterations in PTSD: Structural and functional evidence
- July 22, 2016Source: ALZFORUM
Next Up for Human Brain Imaging: Synaptic Density?
Recent Publications
2023
- The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [(11)C]UCB-J.Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Eur J Nucl Med Mol Imaging. 2023 Nov 13; 2023 Nov 13. PMID: 37955791.
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Cerebellum. 2023 Oct 3; 2023 Oct 3. PMID: 37783917.
- Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender.Koohsari S, Sadabad FE, Pittman B, Gallezot JD, Carson RE, van Dyck CH, Li CR, Potenza MN, Matuskey D. Synapse. 2023 Sep; 2023 Jun 29. PMID: 37382240.
- Improving SUVR quantification by correcting for radiotracer clearance in tissue.Honhar P, Matuskey D, Carson RE, Hillmer AT. J Cereb Blood Flow Metab. 2023 Aug 17; 2023 Aug 17. PMID: 37589538.
- Imaging the brain's immune response to alcohol with [(11)C]PBR28 TSPO Positron Emission Tomography.Raval NR, Angarita G, Matuskey D, Miller R, Drake LR, Kapinos M, Nabulsi N, Huang Y, Carson RE, O'Malley SS, Cosgrove KP, Hillmer AT. Mol Psychiatry. 2023 Aug; 2023 Aug 2. PMID: 37532797.
- A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression.Jauhar S, Arnone D, Baldwin DS, Bloomfield M, Browning M, Cleare AJ, Corlett P, Deakin JFW, Erritzoe D, Fu C, Fusar-Poli P, Goodwin GM, Hayes J, Howard R, Howes OD, Juruena MF, Lam RW, Lawrie SM, McAllister-Williams H, Marwaha S, Matuskey D, McCutcheon RA, Nutt DJ, Pariante C, Pillinger T, Radhakrishnan R, Rucker J, Selvaraj S, Stokes P, Upthegrove R, Yalin N, Yatham L, Young AH, Zahn R, Cowen PJ. Mol Psychiatry. 2023 Aug; 2023 Jun 16. PMID: 37322065.
- Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder.Holmes SE, Asch RH, Davis MT, DellaGioia N, Pashankar N, Gallezot JD, Nabulsi N, Matuskey D, Sanacora G, Carson RE, Blumberg HP, Esterlis I. Biol Psychiatry. 2023 Jun 15; 2022 Nov 8. PMID: 36764853.
- Decreased Synaptic Vesicle Glycoprotein 2A Binding in the Human Postmortem Essential Tremor Cerebellum: Evidence of Reduction in Synaptic Density.Yang Y, Zheng C, Chen B, Hernandez NC, Faust PL, Cai Z, Louis ED, Matuskey D. Res Sq. 2023 May 2; 2023 May 2. PMID: 37205584.
- Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[(18)F]flubatine PET study.Calakos KC, Hillmer AT, Anderson JM, LeVasseur B, Baldassarri SR, Angarita GA, Matuskey D, Kapinos M, Zheng MQ, Huang Y, Cosgrove KP. Neuropsychopharmacology. 2023 Mar; 2023 Jan 21. PMID: 36681758.
- Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.Matuskey D, Gallezot JD, Nabulsi N, Henry S, Torres K, Dias M, Angarita GA, Huang Y, Shoaf SE, Carson RE, Mehrotra S. J Psychopharmacol. 2023 Feb; 2022 Dec 14. PMID: 36515395.
- D3 Receptors and PET Imaging.Koohsari S, Yang Y, Matuskey D. Curr Top Behav Neurosci. 2023. PMID: 35711027.
2022
- Age, gender and body-mass-index relationships with in vivo CB(1) receptor availability in healthy humans measured with [(11)C]OMAR PET.Radhakrishnan R, Worhunsky PD, Zheng MQ, Najafzadeh S, Gallezot JD, Planeta B, Henry S, Nabulsi N, Ranganathan M, Skosnik PD, Pittman B, Cyril D'Souza D, Carson RE, Huang Y, Potenza MN, Matuskey D. Neuroimage. 2022 Dec 1; 2022 Oct 13. PMID: 36243269.
- Systemic inflammation enhances stimulant-induced striatal dopamine elevation in tobacco smokers.Zakiniaeiz Y, Hoye J, Ryan Petrulli J, LeVasseur B, Stanley G, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Chen MK, Matuskey D, Barron DS, Kelmendi B, Fulbright RK, Hampson M, Cosgrove KP, Morris ED. Brain Behav Immun. 2022 Nov; 2022 Sep 1. PMID: 36058419.
- Nicotine Patch Alters Patterns of Cigarette Smoking-Induced Dopamine Release: Patterns Relate to Biomarkers Associated With Treatment Response.Zakiniaeiz Y, Liu H, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Matuskey D, Chen MK, Cosgrove KP, Morris ED. Nicotine Tob Res. 2022 Oct 17. PMID: 35100429.
- Imaging of Synaptic Density in Neurodegenerative Disorders.Carson RE, Naganawa M, Toyonaga T, Koohsari S, Yang Y, Chen MK, Matuskey D, Finnema SJ. J Nucl Med. 2022 Jun. PMID: 35649655.
- Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.Holmes SE, Finnema SJ, Naganawa M, DellaGioia N, Holden D, Fowles K, Davis M, Ropchan J, Emory P, Ye Y, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Mol Psychiatry. 2022 Apr; 2022 Feb 15. PMID: 35165397.
- Imaging Pituitary Vasopressin 1B Receptor in Humans with the PET Radiotracer (11)C-TASP699.Naganawa M, Nabulsi NB, Matuskey D, Henry S, Ropchan J, Lin SF, Gao H, Pracitto R, Labaree D, Zhang MR, Suhara T, Nishino I, Sabia H, Ozaki S, Huang Y, Carson RE. J Nucl Med. 2022 Apr; 2021 Aug 12. PMID: 34385336.
- Recently Abstinent Smokers Exhibit Mood-Associated Dopamine Dysfunction in the Ventral Striatum Compared to Nonsmokers: A [11C]-(+)-PHNO PET Study.Calakos KC, Hillmer AT, Angarita GA, Baldassarri SR, Najafzadeh S, Emery PR, Matuskey D, Huang Y, Cosgrove KP. Nicotine Tob Res. 2022 Mar 26. PMID: 34628508.
- Relationships between dopamine D2/3 receptor availability and social-environmental factors in humans.Calakos KC, Rusowicz A, Pittman B, Gallezot JD, Potenza MN, Cosgrove KP, Matuskey D. Neurosci Lett. 2022 Feb 6; 2022 Jan 17. PMID: 35051435.
2021
- Looking Back at the Next 40 Years of ASD Neuroscience Research.McPartland JC, Lerner MD, Bhat A, Clarkson T, Jack A, Koohsari S, Matuskey D, McQuaid GA, Su WC, Trevisan DA. J Autism Dev Disord. 2021 Dec; 2021 May 27. PMID: 34043128.