William Tyler Frantz, MD, PhD
Hospital ResidentCards
About
Research
Publications
2024
Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis.
Rozen EJ, Frantz W, Wigglesworth K, Vessella T, Zhou HS, Shohet JM. Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis. Mol Cancer Ther 2024 PMID: 38670553, DOI: 10.1158/1535-7163.MCT-23-0741.Peer-Reviewed Original Research In Press
2023
The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in pre-cystic epithelial cells revealing a new target for polycystic kidney disease.
Smith AO, Frantz WT, Preval KM, Edwards YJK, Ceol CJ, Jonassen JA, Pazour GJ. The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in pre-cystic epithelial cells revealing a new target for polycystic kidney disease. MedRxiv 2023 PMID: 38106222, DOI: 10.1101/2023.12.04.23299387.Peer-Reviewed Original ResearchPigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish.
Frantz WT, Iyengar S, Neiswender J, Cousineau A, Maehr R, Ceol CJ. Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish. Elife 2023, 12 PMID: 37021774, DOI: 10.7554/eLife.78942.Peer-Reviewed Original Research In Press
2022
Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease.
Frantz WT, Ceol CJ. Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease. J Invest Dermatol 2022, 142: 499-506.e1. PMID: 35184798, DOI: 10.1016/j.jid.2021.10.016.Peer-Reviewed Educational Materials
2021
Working together: Heterotypic clusters and collective cell migration in melanoma metastasis.
Frantz WT, Ceol CJ. Working together: Heterotypic clusters and collective cell migration in melanoma metastasis. Dev Cell 2021, 56: 2783-2784. PMID: 34699785, DOI: 10.1016/j.devcel.2021.10.003.Commentaries, Editorials and LettersBMP Signaling Promotes Neural Crest Identity and Accelerates Melanoma Onset.
Gramann AK, Frantz WT, Dresser K, Gomes CBF, Lian CG, Deng A, Ceol CJ. BMP Signaling Promotes Neural Crest Identity and Accelerates Melanoma Onset. J Invest Dermatol 2021, 141: 2067-2070.e1. PMID: 33610560, DOI: 10.1016/j.jid.2021.01.021.Peer-Reviewed Original Research In Press
2020
From Tank to Treatment: Modeling Melanoma in Zebrafish.
Frantz WT, Ceol CJ. From Tank to Treatment: Modeling Melanoma in Zebrafish. Cells 2020, 9 PMID: 32455885, DOI: 10.3390/cells9051289.Peer-Reviewed Educational Materials