Zhigui Li, PhD
Associate Research ScientistCards
About
Research
Publications
2023
Dnajb11-Kidney Disease Develops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice
Roy S, Li Z, Guo Z, Long K, Rehrl S, Tian X, Dong K, Besse W. Dnajb11-Kidney Disease Develops from Reduced Polycystin-1 Dosage but not Unfolded Protein Response in Mice. Journal Of The American Society Of Nephrology 2023, 34: 1521-1534. PMID: 37332102, PMCID: PMC10482070, DOI: 10.1681/asn.0000000000000164.Peer-Reviewed Original ResearchKidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease
Boulogne F, Claus L, Wiersma H, Oelen R, Schukking F, de Klein N, Li S, Westra H, van der Zwaag B, van Reekum F, Sierks D, Schönauer R, Li Z, Bijlsma E, Bos W, Halbritter J, Knoers N, Besse W, Deelen P, Franke L, van Eerde A. KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease. European Journal Of Human Genetics 2023, 31: 1300-1308. PMID: 36807342, PMCID: PMC10620423, DOI: 10.1038/s41431-023-01296-x.Peer-Reviewed Original Research
2020
Vulnerability of ARID1A deficient cancer cells to pyrimidine synthesis blockade
Li Z, Mi S, Osagie OI, Ji J, Yang CPH, Schwartz M, Hui P, Huang GS. Vulnerability of ARID1A deficient cancer cells to pyrimidine synthesis blockade. 2020 DOI: 10.1101/2020.10.12.331975.Peer-Reviewed Original Research In Press
2016
miR-200 family promotes podocyte differentiation through repression of RSAD2
Li Z, Yin H, Hao S, Wang L, Gao J, Tan X, Yang Z. miR-200 family promotes podocyte differentiation through repression of RSAD2. Scientific Reports 2016, 6: 27105. PMID: 27251424, PMCID: PMC4890021, DOI: 10.1038/srep27105.Peer-Reviewed Original ResearchAutophagy ameliorates cognitive impairment through activation of PVT1 and apoptosis in diabetes mice
Li Z, Hao S, Yin H, Gao J, Yang Z. Autophagy ameliorates cognitive impairment through activation of PVT1 and apoptosis in diabetes mice. Behavioural Brain Research 2016, 305: 265-277. PMID: 26971628, DOI: 10.1016/j.bbr.2016.03.023.Peer-Reviewed Original ResearchAdenineAnimalsAntibiotics, AntineoplasticApoptosisAutophagyBeclin-1Body WeightCognition DisordersDiabetes Mellitus, ExperimentalDisease Models, AnimalEatingExploratory BehaviorHippocampusHypoglycemic AgentsLong-Term PotentiationMaleMaze LearningMiceMice, Inbred C57BLMicrotubule-Associated ProteinsPerforant PathwayRNA, Long NoncodingStreptozocin
2015
Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25–35-treated differentiated PC12 cells
Xu P, Wang H, Li Z, Yang Z. Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25–35-treated differentiated PC12 cells. Life Sciences 2015, 145: 19-26. PMID: 26679104, DOI: 10.1016/j.lfs.2015.12.018.Peer-Reviewed Original ResearchTriptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta25–35 via the Autophagy Pathway
Xu P, Li Z, Wang H, Zhang X, Yang Z. Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta25–35 via the Autophagy Pathway. PLOS ONE 2015, 10: e0142719. PMID: 26554937, PMCID: PMC4640509, DOI: 10.1371/journal.pone.0142719.Peer-Reviewed Original ResearchEffects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury
Wei M, Li Z, Xiao L, Yang Z. Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury. Molecular Immunology 2015, 68: 261-271. PMID: 26364141, DOI: 10.1016/j.molimm.2015.09.002.Peer-Reviewed Original ResearchAutophagy Alleviates Melamine-Induced Cell Death in PC12 Cells Via Decreasing ROS Level
Wang H, Gao N, Li Z, Yang Z, Zhang T. Autophagy Alleviates Melamine-Induced Cell Death in PC12 Cells Via Decreasing ROS Level. Molecular Neurobiology 2015, 53: 1718-1729. PMID: 25724280, DOI: 10.1007/s12035-014-9073-2.Peer-Reviewed Original ResearchDifferent Expressions of Large-conductance Ca2+-activated K+ Channels in the Mouse Renal Cortex and Hippocampus During Postnatal Development
Xu P, Li Z, Xuan Q, Yang Z. Different Expressions of Large-conductance Ca2+-activated K+ Channels in the Mouse Renal Cortex and Hippocampus During Postnatal Development. Applied Immunohistochemistry & Molecular Morphology 2015, 23: 146-152. PMID: 25390352, DOI: 10.1097/pai.0000000000000006.Peer-Reviewed Original Research
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