Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsRobert Kalyesubula, MBChB
Assistant Professor AdjunctAbout
Research
Publications
2026
Kidney abnormalities in young people living with HIV on dolutegravir-based regimens in Kampala, Uganda
Nasuuna E, Hoffman R, Kalyesubula R, Chikwari C, Weiss H. Kidney abnormalities in young people living with HIV on dolutegravir-based regimens in Kampala, Uganda. AIDS Research And Therapy 2026 PMID: 42251428, DOI: 10.1186/s12981-026-00893-2.Peer-Reviewed Original ResearchEstimated glomerular filtration rateAlbumin-creatinine ratioKidney abnormalitiesElevated albumin-creatinine ratioCystatin C-based estimated glomerular filtration rateDolutegravir (DTG)-based antiretroviral therapyDolutegravir-based regimensCreatinine-based eGFRGlomerular filtration rateAntiretroviral therapySerum creatinineProgression riskFiltration rateAbnormalitiesKidneyProteinuriaHIVLongitudinal studyRegimenRegimensKampalaCreatinineTherapySerumImplementing the commitments of the World Health Assembly kidney health resolution: a key opportunity to improve health for millions
Tonelli M, Kalyesubula R, Tungsanga S, Francis A, Gill J, Lou-Meda R, Luyckx V, Bello A. Implementing the commitments of the World Health Assembly kidney health resolution: a key opportunity to improve health for millions. The Lancet 2026, 407: 2461-2472. PMID: 42155504, DOI: 10.1016/s0140-6736(26)00755-5.Peer-Reviewed Original ResearchConceptsHealth policyKidney replacement therapyNon-communicable disease programmesUN High-Level MeetingMiddle-income countriesHigh-level meetingPrimary carePolitical DeclarationMental healthDisproportionate burdenDisease programmesLow-incomeKidney healthHealthNational strategyPolitical commitmentChronic kidney diseasePractical frameworkEarly detectionCountry experiencesBurdenReturn on investmentKidney diseaseCareCommitmentAbnormal renal function three months after delivery among pre-eclampsia survivors in Sub-Saharan Africa: a prospective cohort study in Uganda
Adroma M, Nsibambi D, Keesiga A, Kalyesubula R, Nakimuli A. Abnormal renal function three months after delivery among pre-eclampsia survivors in Sub-Saharan Africa: a prospective cohort study in Uganda. BMC Pregnancy And Childbirth 2026, 26: 608. PMID: 42021175, PMCID: PMC13235038, DOI: 10.1186/s12884-026-09131-z.Peer-Reviewed Original ResearchConceptsAbnormal renal functionPre-eclampsiaRenal functionPost-deliveryConsequences of pre-eclampsiaEstimated glomerular filtration ratePregnancy-specific hypertensive disorderWomen of African ancestryLong-term follow-upMultivariable modified Poisson regressionGlomerular filtration rateMonths post-deliveryPersistence of hypertensionChronic renal diseaseProspective cohort studyCKD-EPI equationAssociated with abnormal renal functionChronic kidney diseaseResultsA high incidenceHypertensive disordersMale babySub-Saharan AfricaBackgroundPre-eclampsiaConclusionsA substantial proportionCKD-EPIImproving medication availability through mobile wallets and pooled community funds: results from the MoPuleesa hypertension intervention in rural Uganda
Pillai V, Favaretti C, Basenero A, Ntambara J, Wesva I, Jonathan K, Munana R, Cazier J, Bärnighausen T, Schwab J, Wachinger J, Kalyesubula R, McMahon S, Sudharsanan N. Improving medication availability through mobile wallets and pooled community funds: results from the MoPuleesa hypertension intervention in rural Uganda. Health Policy And Planning 2026, 41: 929-941. PMID: 41926709, PMCID: PMC13276264, DOI: 10.1093/heapol/czag044.Peer-Reviewed Original ResearchConceptsMedication availabilityContinuity of careMedical suppliesFrequent shortagesPatient's blood pressure levelResource-constrained settingsHypertension interventionsStatistically significant improvementRural clinicsHealth systemMedication accessMedication shortagesRural UgandaBlood pressure managementNakaseke districtBlood pressure levelsEducation levelEligibility assessmentAdverse selectionStructural barriersMedication gapsMedical costsCommunity-ledFunding poolGovernment pharmaciesWCN26-4821 TAST-SHIFTING URINE OUTPUT MONITORING to CAREGIVERS CUTS IN-HOSPITAL ACUTE KIDNEY INJURY MORTALITY in UGANDA
MULEMA E, Biraro I, Kiggundu D, Akankunda P, Bodnar B, Kalyesubula R. WCN26-4821 TAST-SHIFTING URINE OUTPUT MONITORING to CAREGIVERS CUTS IN-HOSPITAL ACUTE KIDNEY INJURY MORTALITY in UGANDA. Kidney International Reports 2026, 11: 103975. DOI: 10.1016/j.ekir.2026.103975.Peer-Reviewed Original ResearchClinical and laboratory characteristics of adolescents and young adults with sickle cell disease at steady state in Uganda
Ssekandi A, Namazzi R, Muwonge H, Kalyesubula R, Munabi I, Sekaggya-Wiltshere C, Namaganda A, Kimuli I, Akugizibwe R, Kasujja H, Mukunya D, Ndeezi G, Kiguli S. Clinical and laboratory characteristics of adolescents and young adults with sickle cell disease at steady state in Uganda. PLOS Global Public Health 2026, 6: e0005898. PMID: 41911181, PMCID: PMC13035150, DOI: 10.1371/journal.pgph.0005898.Peer-Reviewed Original ResearchSickle cell diseaseLaboratory characteristicsCell diseaseHospital-based cross-sectional studyCharacteristics of adolescentsMulago National Referral HospitalYoung adultsDiastolic blood pressureNational Referral HospitalCross-sectional studyMean hemoglobinSubclinical abnormalitiesSystemic morbidityHemodynamic profileHematologic abnormalitiesAcute complicationsReferral hospitalBlood pressureHeart rateMedication useAbnormalitiesMmHgSub-Saharan AfricaAdolescentsDiseaseKidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans
Kamiza A, Chikowore T, Chen G, Ojewunmi O, Machipisa T, Zhou F, Mayanja R, Toure S, Soremekun O, Kintu C, Nakabuye M, Koprulu M, Kalungi A, Kalyesubula R, Salako B, Nashiru O, Corpas M, Robinson-Cohen C, Franceschini N, Pattaro C, Köttgen A, Nitsch D, Langenberg C, Tcheandjieu C, Nyirenda M, Morris A, Asimit J, Zeggini E, Rotimi C, Ramsay M, Adeyemo A, Fabian J, Crampin A, Brandenburg J, Fatumo S. KidneyGenAfrica multi-cohort Genome-wide association study and polygenic prediction of kidney function in 110,000 Africans. Nature Communications 2026, 17: 2599. PMID: 41667462, PMCID: PMC13003101, DOI: 10.1038/s41467-026-69367-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAfricaAfrican PeopleApolipoprotein L1Black or African AmericanBlack PeopleCohort StudiesFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyGlomerular Filtration RateHumansKidneyKidney DiseasesMaleMiddle AgedMultifactorial InheritancePolymorphism, Single NucleotideWhiteConceptsGenome-wide association study meta-analysisPolygenic predictionGenome-wide significant lociGenome-wide association studiesDiverse African populationsAfrican ancestry individualsPhenome-wide analysisGenetically similar populationsPopulations of African ancestrySignificant lociIndependent lociFine-mappingGenetic architectureAssociation studiesGenomic researchGenetic studiesHigh-risk variantsLociContinental AfricaImmunological traitsPolygenic scoresAfrican ancestryPleiotropic effectsPhenome-wideAfrican populationsKidney disease screening at ART initiation among adults with HIV in Uganda: A missed priority for a high-risk population
Kansiime G, Baluku J, Nuwagira E, Kanyesigye M, Obwoya P, Muhindo R, Muyindike W, Tusingwire P, Mugerwa H, Odera M, Busuulwa M, Ssemakadde M, Atukunda E, Bajunirwe F, Kalyesubula R, Siedner M. Kidney disease screening at ART initiation among adults with HIV in Uganda: A missed priority for a high-risk population. PLOS Global Public Health 2026, 6: e0005106. PMID: 41628191, PMCID: PMC12863478, DOI: 10.1371/journal.pgph.0005106.Peer-Reviewed Original ResearchAntiretroviral therapy initiationAntiretroviral therapyKidney disease screeningKidney diseaseAntiretroviral therapy regimensNational guidelinesTenofovir disoproxil fumarateDisease screeningSerum creatinine testsHigh-risk populationTDF useOpportunistic infectionsDisoproxil fumarateHIV clinicLogistic regression modelsMale sexRenal screeningScreening oddsClinical dataGuideline uptakeMultilevel barriersScreening ratesCreatinine testingRural clinicsPWHClinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis
Meena P, Singla V, Deshpande A, Kasturi U, Khan E, Kumar V, Kalyesubula R. Clinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis. Malaria Journal 2026, 25: 122. PMID: 41620769, PMCID: PMC12947477, DOI: 10.1186/s12936-025-05777-w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSevere complications of malariaComplication of malariaAcute kidney injurySevere complicationsP. vivaxAdult patientsKidney injuryPlasmodium falciparumLong-term nephrology follow-upAssociated with P. vivaxLong-term kidney outcomesPlasmodium vivax infectionEndemic regionsAcute cortical necrosisIncidence of AKINephrology follow-upSerum creatinine thresholdAcute tubular necrosisChronic kidney diseaseSystematic reviewMethodsA systematic reviewSevere malariaCerebral malariaMalaria burdenThrombotic microangiopathyComorbidities associated with early chronickidney disease among young people living withHIV in Uganda. A nested case control study
Nasuuna E, Tomlinson L, Kalyesubula R, Castelnuovo B, Nanyeenya N, Chikwari C, Weiss H. Comorbidities associated with early chronickidney disease among young people living withHIV in Uganda. A nested case control study. BMC Nephrology 2026, 27: 108. PMID: 41545860, PMCID: PMC12892556, DOI: 10.1186/s12882-025-04719-7.Peer-Reviewed Original ResearchHIV viral loadOdds ratioViral loadClinical factorsCD4 T-cell countPatterns of comorbiditiesConclusionThe patternDetectable HIV viral loadCase-control studyAssociation of CKDT-cell countsAssociated with high mortalityYoung peopleMultiple body systemsFasting glucose levelsHigher mean corpuscular volumeYPLHIVIntroductionChronic kidney diseaseART clinicChronic comorbiditiesLogistic regressionViral suppressionConfidence intervalsMean corpuscular volumeParathyroid hormone