Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsHuabing Li, PhD
Assistant Professor AdjunctAbout
Research
Publications
2026
RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control
Zhang Y, Kan C, Yang X, Hao Y, Cai X, Yang M, Zhang Q, Wang Z, Jiang N, Wang L, Li H, Zhou J. RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control. Advanced Science 2026, e16653. PMID: 42210780, DOI: 10.1002/advs.202516653.Peer-Reviewed Original Researchm6A RNA modification guides alternative polyadenylation to maintain T cell quiescence
Zhang X, Li H, Wang G, Miao S, Hao Y, Li S, Li B, Xiao H, Su B, Wu Y, Ye Y, Li H. m6A RNA modification guides alternative polyadenylation to maintain T cell quiescence. Science Advances 2026, 12: eaea4983. PMID: 42127188, PMCID: PMC13170632, DOI: 10.1126/sciadv.aea4983.Peer-Reviewed Original ResearchtRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy
Wang X, Wang X, Li H, Liu S, Lu Y, Chen H, Cai X, Su S, Li B, Liu R, Hu W, Zhu X, Zhang J, Ye Y, Li H. tRNA m1A modification orchestrates STING translation in macrophages to enhance antitumor immunity and CAR-macrophage immunotherapy. Cellular & Molecular Immunology 2026, 23: 261-272. PMID: 41535541, PMCID: PMC12949049, DOI: 10.1038/s41423-025-01383-7.Peer-Reviewed Original ResearchIntrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial
Li X, Shang X, Liu J, Zhang Y, Jia X, Li H, Wang Y, Gao J, Ma X, Zhang X, Rong X, Gan W, Zhang Y, Chen J, Wang L, Bao Z, He L, Yan X, Liu Y, Shao J, Xiao Z, Wang Z, Zhu H, Wang Z, Wu Y, Huang Y. Intrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial. Nature Communications 2026, 17: 1362. PMID: 41495049, PMCID: PMC12877024, DOI: 10.1038/s41467-025-68112-6.Peer-Reviewed Original ResearchAdultAgedAnimalsBrain NeoplasmsCell Line, TumorCRISPR-Cas SystemsFemaleGene EditingGlioblastomaGliomaGraft vs Host DiseaseHumansImmunotherapy, AdoptiveInterleukin-13 Receptor alpha2 SubunitKiller Cells, NaturalMaleMiceMiddle AgedNeoplasm Recurrence, LocalReceptors, Chimeric AntigenT-LymphocytesTreatment OutcometRNA m1A modification is essential for gut homeostasis and function of group 3 innate lymphoid cells
Li J, Tang Z, Chen Y, Cai X, Wu L, Wang G, Kan C, Li B, Su B, Li H, Chu C, Li H. tRNA m1A modification is essential for gut homeostasis and function of group 3 innate lymphoid cells. Cell Discovery 2026, 12: 1. PMID: 41484094, PMCID: PMC12764812, DOI: 10.1038/s41421-025-00850-9.Peer-Reviewed Original ResearchRNA epigenetic modification for immune cell reprogramming and therapeutic translation
Zhang Y, Liu A, Li H. RNA epigenetic modification for immune cell reprogramming and therapeutic translation. Fundamental Research 2026 DOI: 10.1016/j.fmre.2025.12.028.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2025
RNA modifications in intestinal macrophages: Implications for gut immunity and inflammation
Su M, Fan J, Li H. RNA modifications in intestinal macrophages: Implications for gut immunity and inflammation. Genes & Diseases 2025, 13: 101881. PMID: 41376856, PMCID: PMC12688690, DOI: 10.1016/j.gendis.2025.101881.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia
Huang H, Li X, Luo J, Gao C, Yang M, Xu J, Xie T, Chen Z, Wang D, Wang Y, Li H, Huang J, Liu Y, Zhang H, Ntziachristos P, Zhao Y, Qing G, Liu H. FTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia. Science Advances 2025, 11: eadq3052. PMID: 40435251, PMCID: PMC12118595, DOI: 10.1126/sciadv.adq3052.Peer-Reviewed Original ResearchRNA cytidine acetyltransferase NAT10 maintains T cell pathogenicity in inflammatory bowel disease
Li H, Cai X, Xu C, Yang X, Song X, Kong Y, Yang M, Wu Q, Zheng S, Shao Y, Wang P, Zhou J, Li H. RNA cytidine acetyltransferase NAT10 maintains T cell pathogenicity in inflammatory bowel disease. Cell Discovery 2025, 11: 19. PMID: 40038243, PMCID: PMC11880361, DOI: 10.1038/s41421-025-00781-5.Peer-Reviewed Original ResearchAcute inflammation induces acute megakaryopoiesis with impaired platelet production during fetal hematopoiesis.
Hu X, He Y, Li S, Jiang Y, Yu R, Wu Y, Fu X, Song Y, Lin C, Shi J, Li H, Gao Y. Acute inflammation induces acute megakaryopoiesis with impaired platelet production during fetal hematopoiesis. Development 2025, 152 PMID: 39817838, DOI: 10.1242/dev.204226.Peer-Reviewed Original Research
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