Claudia Francoise-Eve Kirsch, FACR, MD
Professor of Radiology and Biomedical ImagingCards
About
Research
Publications
2026
214. 7T MRI Reveals Morphological Changes and Associations Between Neuropsychological Function and Brain Volumes in Long-COVID
Desai J, Herb M, Verma G, Saju S, Khegai O, Becker J, Kirsch C, Zhu Y, Jacob Y, Delman B, Seifert A, Balchandani P, Rashid S. 214. 7T MRI Reveals Morphological Changes and Associations Between Neuropsychological Function and Brain Volumes in Long-COVID. Biological Psychiatry 2026, 99: s190. DOI: 10.1016/j.biopsych.2026.03.448.Peer-Reviewed Original Research“Mind the Gap”—enlarged perivascular spaces as a potential magnetic resonance imaging biomarker of impaired glymphatic clearance in brain disorders
Kirsch C, Herb M, Verma G, Balchandani P. “Mind the Gap”—enlarged perivascular spaces as a potential magnetic resonance imaging biomarker of impaired glymphatic clearance in brain disorders. Frontiers In Cellular Neuroscience 2026, 20: 1741115. PMID: 41993675, PMCID: PMC13079593, DOI: 10.3389/fncel.2026.1741115.Peer-Reviewed Original ResearchEndovascular shunt feasibility in shunt responsive idiopathic intracranial hypertension: morphometric radiographic analysis
Koo A, Talati K, Vajipayajula D, Castaneda A, Amllay A, Sujijantarat N, Kirsch C, Malhotra A, Hebert R, Falcone G, Sheth K, de Havenon A, Kan P, Heilman C, Malek A, Matouk C. Endovascular shunt feasibility in shunt responsive idiopathic intracranial hypertension: morphometric radiographic analysis. Journal Of NeuroInterventional Surgery 2026, jnis-2025-024793. PMID: 41611529, DOI: 10.1136/jnis-2025-024793.Peer-Reviewed Original ResearchIdiopathic intracranial hypertensionInferior petrosal sinusVentricular shuntCerebellopontine angleIntracranial hypertensionEndovascular shuntSingle center studyCerebrospinal fluid shuntsProportion of patientsPetrosal sinusSupratentorial shuntVenous anatomyCenter studyRadiographic parametersPatientsRadiographic analysisRadiographic imagesShuntHypertensionUnique populationMRI imagesMechanical shuntCandidacyCerebellopontineSinusBeyond the AJR: Melding Artificial Intelligence and MRI to Find Focal Cortical Dysplasia.
Kirsch C, Bronen R. Beyond the AJR: Melding Artificial Intelligence and MRI to Find Focal Cortical Dysplasia. American Journal Of Roentgenology 2026, 226: e2533104. PMID: 40304677, DOI: 10.2214/ajr.25.33104.Commentaries, Editorials and Letters
2025
Harnessing Artificial Intelligence in Head and Neck Oncology Practice Data, Diagnosis, and Therapy
Rao K, Kirsch C, Mahmood H, Simon C. Harnessing Artificial Intelligence in Head and Neck Oncology Practice Data, Diagnosis, and Therapy. Otolaryngologic Clinics Of North America 2025, 59: 271-289. PMID: 41162240, DOI: 10.1016/j.otc.2025.09.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsA Systematic Approach to the Evaluation of Lumbosacral Plexus MRI: Indications, Protocol, Anatomy, and Pathology.
Rahmani S, Hamilton C, Dixe de Oliveira Santo I, Nguyen J, Zaree O, Kenny-Howell C, Kirsch C, Tu L. A Systematic Approach to the Evaluation of Lumbosacral Plexus MRI: Indications, Protocol, Anatomy, and Pathology. American Journal Of Neuroradiology 2025, 47: 300-312. PMID: 40854685, PMCID: PMC12867042, DOI: 10.3174/ajnr.a8976.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPlexus magnetic resonance imagingMagnetic resonance imagingLumbosacral plexusTurbo spin echoChronic inflammatory demyelinating polyneuropathyVolumetric Interpolated Breath-hold ExaminationInflammatory demyelinating polyneuropathySpin echoAcquisition single-shot turbo spin-echoPeripheral nerve disordersSingle-shot turbo spin-echoHalf-Fourier acquisition single-shot turbo spin-echoDiffusion-weighted imagingMagnetic resonance imaging protocolShort-tau inversion recoveryBreath-hold examinationTau inversion recoveryApplication-optimized contrastsFlip angle evolutionsSteady-state free precessionCompressive etiologyImaging of Midfacial and Orbital Trauma
Kirsch C. Imaging of Midfacial and Orbital Trauma. 2025, 93-106. DOI: 10.1007/978-3-031-78916-8_7.ChaptersComputed tomographyLe Fort classificationZygomaticomaxillary complexFacial skeletonOptic nerve involvementZygomatic complex fracturesBony elementsInferior nasal conchaMulti-planar imagingZygomatic boneNasal boneNaso-orbito-ethmoidal regionNerve involvementHigh-speed traumaMotor vehicle collisionsClinical featuresMidfacial traumaNasolacrimal ductOrbital traumaOptimal treatmentNasal projectionOrbital anatomyRadiographic featuresRadiographic findingsSurgical planningImaging of Midfacial and Orbital Trauma
Kirsch C. Imaging of Midfacial and Orbital Trauma. 2025, 1-14. DOI: 10.1007/978-3-030-44092-3_7-2.ChaptersComputed tomographyLe Fort classificationZygomaticomaxillary complexFacial skeletonOptic nerve involvementZygomatic complex fracturesBony elementsInferior nasal conchaMulti-planar imagingZygomatic boneNasal boneNaso-orbito-ethmoidal regionNerve involvementHigh-speed traumaMotor vehicle collisionsClinical featuresMidfacial traumaNasolacrimal ductOrbital traumaOptimal treatmentNasal projectionOrbital anatomyRadiographic featuresRadiographic findingsSurgical planningUtilization, detection rate, and pathologies on lumbosacral plexus MRI: a 25-year institutional experience
Rahmani S, Hamilton C, Nguyen J, Zaree O, Kenny-Howell C, Kirsch C, Tu L. Utilization, detection rate, and pathologies on lumbosacral plexus MRI: a 25-year institutional experience. Clinical Imaging 2025, 125: 110529. PMID: 40494183, DOI: 10.1016/j.clinimag.2025.110529.Peer-Reviewed Original ResearchPlexus MRIAbnormal findingsImaging findingsClinical indicationsPlexus magnetic resonance imagingPredictors of abnormal findingsMRI examsAssociated with abnormal findingsAbnormal radiological featuresConfounding clinical featuresTertiary referral centerAbnormal imaging findingsAbnormal MRI findingsEvaluated clinical indicatorsNerve sheath tumorsClinically relevant pathologyMultivariate logistic regressionPercentage of casesMagnetic resonance imagingInfectious/inflammatory etiologyLumbar radiculopathySheath tumorsLumbosacral plexopathyPatient ageReferral center
2024
Seven-tesla magnetic resonance imaging of the nervus terminalis, olfactory tracts, and olfactory bulbs in COVID-19 patients with anosmia and hypogeusia
Kirsch C, Khurram S, Lambert D, Belani P, Pawha P, Alipour A, Rashid S, Herb M, Saju S, Zhu Y, Delman B, Lin H, Balchandani P. Seven-tesla magnetic resonance imaging of the nervus terminalis, olfactory tracts, and olfactory bulbs in COVID-19 patients with anosmia and hypogeusia. Frontiers In Radiology 2024, 4: 1322851. PMID: 39410969, PMCID: PMC11473298, DOI: 10.3389/fradi.2024.1322851.Peer-Reviewed Original ResearchCOVID-19 patientsOlfactory bulbOlfactory tractNervus terminalisT2 hyperintensityAngiotensin-converting enzyme-2Olfactory nerveHealthy controlsSARS-CoV-2White matter T2 hyperintensitiesBoard-certified neuroradiologistsPotential entry sitesExpression of angiotensin-converting enzyme-2Viral entry siteBrain volume lossCentral nervous systemMagnetic resonance imagingBrainstem involvementT2 hyperintensitiesAbsence of NTOlfactory epitheliumVolume lossT2 signalACE-2 receptorHypogeusia
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Radiology & Biomedical Imaging
330 Cedar Street
New Haven, CT 06520
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