Publications
2024
- Peer-Reviewed Original ResearchNew-onset conditionsInternal tremorLong COVID symptomsCOVID symptomsNon-Hispanic whitesCross-sectional studyQuality of lifeVisual analogue scaleWorse healthHealth statusStudy participantsDemographic characteristicsAnalogue scaleOutcome variablesNeurological conditionsLong COVIDMast cell disordersTreatment experienceHealthComorbiditiesSymptomsMedian agePeopleCell disorders
Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19
McAlpine L, Zubair A, Joseph P, Spudich S. Case-Control Study of Individuals With Small Fiber Neuropathy After COVID-19. Neurology Neuroimmunology & Neuroinflammation 2024, 11: e200244. PMID: 38630952, PMCID: PMC11087026, DOI: 10.1212/nxi.0000000000200244.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsInvasive cardiopulmonary exercise testingSmall fiber neuropathyCase-control studyFiber neuropathySkin biopsiesClinical response to treatmentNeurovascular dysregulationTreated with IVIGRetrospective chart reviewCase-control study of individualsRetrospective cohort studyResponse to treatmentCardiopulmonary exercise testingClass III evidenceMyalgic encephalomyelitis/chronic fatigue syndromeIVIG groupClinical responseNeuropathic symptomsChart reviewIVIGStudy of individualsCohort studyIII evidenceClinical trialsCOVID-19 illnessFocal White Matter Damage in Individuals with Cognitive Impairment After COVID-19 (P11-13.004)
McAlpine L, Nelson A, Chiarella J, Lacadie C, Farhadian S, Constable T, Spudich S. Focal White Matter Damage in Individuals with Cognitive Impairment After COVID-19 (P11-13.004). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000204666.Peer-Reviewed Original ResearchVirology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis
Zubair A, McAlpine L, Gobeske K. Virology, ecology, epidemiology, pathology, and treatment of eastern equine encephalitis. Journal Of The Neurological Sciences 2024, 457: 122886. PMID: 38278094, DOI: 10.1016/j.jns.2024.122886.Peer-Reviewed Original ResearchMeSH Keywords and Concepts
2023
Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation
Farhadian S, Reisert H, McAlpine L, Chiarella J, Kosana P, Yoon J, Spudich S. Self-Reported Neuropsychiatric Post–COVID-19 Condition and CSF Markers of Neuroinflammation. JAMA Network Open 2023, 6: e2342741. PMID: 37948085, PMCID: PMC10638645, DOI: 10.1001/jamanetworkopen.2023.42741.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsPlasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions
Zubair A, Rethana M, Ma A, McAlpine L, Abulaban A, Munro B, Patwa H, Nowak R, Roy B. Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions. Journal Of Clinical Neuromuscular Disease 2023, 25: 11-17. PMID: 37611265, DOI: 10.1097/cnd.0000000000000439.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsNeuro-immunological diseaseIntravenous immunoglobulinAutoimmune neurological disordersAutoimmune neuromuscular disorderAdult patientsElderly patientsNeurological disordersNeuromuscular disordersChronic inflammatory demyelinating polyradiculoneuropathyNational Inpatient Sample databaseNational Inpatient Sample datasetInflammatory demyelinating polyradiculoneuropathySafe therapeutic choiceRetrospective chart reviewAppropriate clinical settingSide effect profileDemyelinating polyradiculoneuropathyIVIG useChart reviewYounger patientsMyasthenia gravisEffect profileMedical historyPrimary diagnosisTherapeutic choiceNeurological sequelae of vaccines
McAlpine L, Zubair A. Neurological sequelae of vaccines. Neurological Sciences 2023, 44: 1505-1513. PMID: 36622478, PMCID: PMC9838503, DOI: 10.1007/s10072-022-06581-z.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsGuillain-Barre syndromeInfectious diseasesNeurological sequelaeAcute disseminated encephalomyelitisSystemic immune activationMild adverse reactionsDisseminated encephalomyelitisLocal sorenessNeurologic sequelaeTransverse myelitisAdverse eventsRecent vaccinationImmune activationAdverse reactionsDisease onsetPotential pathogenesisSafe optionPotential treatmentEarly identificationVaccineSequelaeRapid diagnosisAdverse effectsTypical symptomsDisease
2022
Anti-SARS-CoV-2 and Autoantibody Profiling of a COVID-19 Patient With Subacute Psychosis Who Remitted After Treatment With Intravenous Immunoglobulin
McAlpine L, Lifland B, Check J, Angarita G, Ngo T, Chen P, Dandekar R, Alvarenga B, Browne W, Pleasure S, Wilson M, Spudich S, Farhadian S, Bartley C. Anti-SARS-CoV-2 and Autoantibody Profiling of a COVID-19 Patient With Subacute Psychosis Who Remitted After Treatment With Intravenous Immunoglobulin. Biological Psychiatry 2022, 93: e25-e29. PMID: 36481066, PMCID: PMC9722219, DOI: 10.1016/j.biopsych.2022.09.007.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsIntravenous Immune Globulins vs Plasma Exchange Usage in Patients with Neuromuscular and Neuro-immunological Conditions (P4-13.007)
Rethana M, Zubair A, Ma A, McAlpine L, Abulaban A, Nowak R, Roy B. Intravenous Immune Globulins vs Plasma Exchange Usage in Patients with Neuromuscular and Neuro-immunological Conditions (P4-13.007). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.2392.Peer-Reviewed Original ResearchCase Series: Post-COVID Small Fiber Neuropathy (P9-9.002)
McAlpine L, Zubair A, Spudich S. Case Series: Post-COVID Small Fiber Neuropathy (P9-9.002). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.348.Peer-Reviewed Original Research
2021
Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients (2402)
McAlpine L, Zubair A, Maran I, Chojecka P, Lleva P, Jasne A, Navaratnam D, Matouk C, Schindler J, Chun H, Lee A, Spudich S, Sharma R, Sansing L. Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients (2402). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.2402.Peer-Reviewed Original Research
Abstracts
2024
McAlpine L, Nelson A, Chiarella J, Fulbright R, Lacadie C, Constable T, Spudich S. Focal White Matter Damage in Individuals with Cognitive Impairment After COVID-19. American Academy of Neurology Annual Meeting. Denver, April 2024.
Son J,* Hu C,* McAlpine L,* Bar-Or A, Dahl M, Ferreira Brito S, Kavak K, Onomichi K, Perrone C, Riley C, Song E, Walker E, Weinstock Guttman B, De Jager P, Longbrake E, and Xia Z. Post-COVID Conditions in People with Multiple Sclerosis: A Cross-sectional Multicenter Study. American Academy of Neurology Annual Meeting. Denver, April 2024.
McAlpine L, Nelson A, Chiarella J, Fulbright R, Qiu M, Lacadie C, Farhadian S, Constable T, Spudich S. Focal Cerebral Hypoperfusion in Individuals with Cognitive Impairment After COVID-19. Conference on Retroviruses and Opportunistic Infections. Denver, March 2024.
McAlpine L, Chiarella J, Nelson A, Orlinick B, Grubman A, Das B, Farhadian S, Spudich S. Vascular Inflammation in Neuropsychiatric Post-Acute Sequelae of COVID-19. Conference on Retroviruses and Opportunistic Infections. Denver, March 2024.
2023
McAlpine L, Nelson A, Chiarella J, Fulbright R, Qiu M, Farhadian S, Constable T, Spudich S. Focal Cerebral Hypoperfusion in Individuals with Cognitive Impairment After COVID-19. Demystifying Long COVID-19 International Conference. Madrid, December 2023.
McAlpine L, Reisert H, Das B, Nelson A, Chiarella J, Farhadian S, Spudich S. Vascular Inflammation in Neuropsychiatric Post-Acute Sequelae of COVID-19. Demystifying Long COVID-19 International Conference. Madrid, December 2023.
McAlpine L, Reisert H, Das B, Nelson A, Chiarella J, Farhadian S, Serena Spudich S. Vascular Inflammation in Neuropsychiatric Post-Acute Sequelae of COVID-19. North American Vascular Biology Organization Annual Meeting. Newport, October 2023.
Farhadian S, McAlpine L, Reisert H, Yoon J, Chiarella J, Kosana P, Chen P, Blennow K, Chakravarty D, Pleasure S, Wilson M, Gisslen M, Zetterberg H, and Spudich S. CSF & Plasma Soluble Biomarkers in Neuro-PASC: Preliminary Results from The COVID Mind Study. Conference on Retroviruses and Opportunistic Infections. Seattle, February 2023.
McAlpine L, Dastgheyb R, Chiarella J, Fulbright R, Constable T, Lacadie C, Yoon H, Reisert H, Farhadian S, Spudich S, and Rubin L. Cognitive, Motor, & Negative Valence Systems in Neurologic PASC: A Preliminary Study. Conference on Retroviruses and Opportunistic Infections. Seattle, February 2023.
2022
Yoon J, McAlpine L, Naeem A, Chiarella J, Catalano A, Gisslen M, Zetterberg H, Walsh H, Shin S, Baik E, Spudich S, and Farhadian F. CSF and blood biomarkers in neurologic postacute sequelae of SARS-CoV-2 infection. The Viral Infections & Inflammation Workshop. Washington, D.C., September 2022.
Rethana M, Zubair A, Ma A, McAlpine L, Abulaban A, Nowak R, Roy B. Intravenous Immune Globulins vs Plasma Exchange Usage in Patients with Neuromuscular and Neuro-immunological Conditions. American Academy of Neurology Annual Meeting. Seattle, April 2022.
McAlpine L, Zubair A, Spudich S. Case Series: Post-COVID Small Fiber Neuropathy. American Academy of Neurology Annual Meeting. Seattle, April 2022.
McAlpine L, Chiarella J, Walsh H, Shin S, Baik E, Yoon J, Naeem A, Blennow K, Gisslen M, Zetterberg H, Wilson M, Pleasure S, Bartley C, Spudich S, and Farhadian S. CSF and Blood Analyses in Participants with Post-COVID-19 Neuropsychiatric Symptoms. Conference on Retroviruses and Opportunistic Infections. Denver, February 2022.
2021
McAlpine L, Zubair A, Maran I, Chojecka P, Lleva P, Jasne A, Navaratnam D, Matouk C, Schindler J, Sheth K, Chun H, Lee A, Spudich S, Sharma R, and Sansing L. Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients. American Academy of Neurology Annual Meeting. Virtual, April 2021.
McAlpine L, Lifland B, Check J, Angarita G, Ngo T, Pleasure S, Wilson M, Spudich S, Farhadian S, and Bartley. Remission of abrupt-onset psychosis after treatment with intravenous immunoglobulin in a COVID-19 patient with an anti-neuronal autoantibody. Society of Biological Psychiatry Annual Meeting. Virtual, April 2021.
Bartley C, Song E, Dandekar R, Zamecnik C, Ngo T, Sunshine S, Wu W, Vazquez S, Alvarenga B, Hawes I, Wapniarski A, Loudermilk R, Johns C, McAlpine L, Lifland B, Pak J, Derisilab J, Wietstock S, Spudich S, Farhadian S, Pleasure S, and Wilson M. Intrathecal SARS-CoV-2 and anti-neural antibodies in COVID-19 patients with neuropsychiatric symptoms. American Academy of Neurology Annual Meeting. Virtual, April 2021.
Song E, Bartley C, Chow R, Ngo T, Jiang R, Zamecnik C, Dandekar R, McAlpine L, Spudich S, DeRisi J, Iwasaki A, Pleasure S, Wilson M, and Farhadian S. Divergent and Self-Reactive Immune responses in the CNS of COVID-19 Patients. Conference on Retroviruses and Opportunistic Infections. Virtual, March 2021.