2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressLongitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study. The Science Of The Total Environment 2023, 900: 165780. PMID: 37495154, DOI: 10.1016/j.scitotenv.2023.165780.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionCohort StudiesEnvironmental ExposureHumansNitrogen DioxideOzoneParticulate MatterConceptsExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAssociated with air pollutionExposure windowsBonferroni-corrected P value thresholdPopulation-based Cooperative Health ResearchShort-term exposure to air pollutionAir pollutionCooperative Health ResearchAir pollution exposureP-value thresholdAssociated with cardiopulmonary diseasesHealth researchLongitudinal associationsMedium-term exposureStudy participantsPollution exposureCohort studyCovariate-adjustedS4 surveyParticipantsAlterations of serum metabolitesSerum metabolitesPollution
2022
Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4
Ni W, Wolf K, Breitner S, Zhang S, Nikolaou N, Ward-Caviness C, Waldenberger M, Gieger C, Peters A, Schneider A. Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4. Environmental Science And Technology 2022, 56: 17815-17824. PMID: 36442845, PMCID: PMC9775210, DOI: 10.1021/acs.est.2c04486.Peer-Reviewed Original ResearchConceptsLeukocyte telomere lengthAssociated with shorter leukocyte telomere lengthShorter leukocyte telomere lengthKORA F3Cohort studyParticipant's residential addressMeta-analysisShort-term effectsPopulation-based studyPopulation-based settingInterquartile rangeShort-term associationsResidential addressesKORA F4Telomere lengthAge-related morbidityAdult populationPCR-based methodsEffects of air temperatureKORADaily air temperatureQuantitative PCR-based methodCohortParticipantsGeneralized additive modelLongitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study. Environment International 2022, 170: 107632. PMID: 36402035, DOI: 10.1016/j.envint.2022.107632.Peer-Reviewed Original ResearchConceptsLong-term exposure to air pollutionExposure to air pollutionLand-use regressionAir pollutionPhosphatidylcholine acyl-alkylParticulate matterLong-term exposure to ambient air pollutionAverage concentrations of ultrafine particlesExposure to ambient air pollutionEstimate annual average concentrationsAssociated with cardiopulmonary diseasesAmbient air pollutionConcentrations of ultrafine particlesPopulation-based Cooperative Health ResearchAmbient pollutantsLand-useAerodynamic diameterCooperative Health ResearchPollutionS4 surveyCoarse particlesFine particlesMixed-effects regression modelsUltrafine particlesNitrogen oxidesShort-term effects of cold spells on plasma viscosity: Results from the KORA cohort study in Augsburg, Germany
Ni W, Schneider A, Wolf K, Zhang S, Chen K, Koenig W, Peters A, Breitner S. Short-term effects of cold spells on plasma viscosity: Results from the KORA cohort study in Augsburg, Germany. Environmental Pollution 2022, 302: 119071. PMID: 35231540, DOI: 10.1016/j.envpol.2022.119071.Peer-Reviewed Original ResearchConceptsPlasma viscosityCardiac eventsDistributed lag nonlinear modelsKORA cohort studyAdverse cardiac eventsCross-sectional studyLag 0Cohort studyCardiovascular diseaseShort-term effectsSignificant associationConsecutive daysBlood parametersAdverse effectsCold exposureExposure dataLag nonlinear modelsMultiple mechanismsDaysSup
2021
Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Ward-Caviness C, Diaz-Sanchez D, Kraus W, Hauser E, Schwartz J, Peters A, Schneider A. Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort. Environmental Pollution 2021, 275: 116663. PMID: 33581627, DOI: 10.1016/j.envpol.2021.116663.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersCohort StudiesHumansMyocardial InfarctionMyocardiumParticulate MatterTroponin TConceptsFine particulate matterParticulate matterDaily PM<sub>2.5</sub> concentrationsShort-term exposure to ambient fine particulate matterAcute PM<sub>2.5</sub> exposureAssociation of PM<sub>2.5</sub> wiElevated PM<sub>2.5</sub>Exposure to ambient fine particulate matterExposure to fine particulate matterAmbient fine particulate matterParticipant's residential addressCTnT testNeural network-based hybrid modelResidential addressesElevated indicatorsMeasurement of NT-pro-BNPConcentrationMatterMyocardial infarction symptomsDuke University HospitalInfarction symptomsRural areasOdds ratioCoronary eventsInterquartile rangeLongitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study
Zhang S, Mwiberi S, Pickford R, Breitner S, Huth C, Koenig W, Rathmann W, Herder C, Roden M, Cyrys J, Peters A, Wolf K, Schneider A. Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study. The Lancet Planetary Health 2021, 5: e39-e49. PMID: 33421408, DOI: 10.1016/s2542-5196(20)30275-8.Peer-Reviewed Original ResearchConceptsLong-term air pollution exposureAir pollution exposureAnnual average air pollutant concentrationsAssociation of air pollutionAverage air pollutant concentrationsPollution exposureLongitudinal associationsType 2 diabetesAir pollutant concentrationsLand-use regression modelsAssociated with air pollution exposureExposure to air pollutionCooperative Health ResearchAmbient air pollutionRegression modelsConcentrations of fasting insulinKORA F4German Federal Ministry of EducationHealth researchIQR incrementAir pollutionAnnual rateKORA cohortDevelopment of type 2 diabetesKORA S4