2023
Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration
Ni W, Nikolaou N, Ward-Caviness C, Breitner S, Wolf K, Zhang S, Wilson R, Waldenberger M, Peters A, Schneider A. Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration. Environment International 2023, 178: 108109. PMID: 37517177, PMCID: PMC10656697, DOI: 10.1016/j.envint.2023.108109.Peer-Reviewed Original ResearchConceptsEpigenetic age accelerationGeneralized estimating equationsExposure to high air temperaturesAge accelerationAverage air temperatureDistributed lag non-linear modelMeasures of epigenetic age accelerationAir temperatureHuman health worldwideExposure to air temperaturesSpatial variationClimate changeEffects of air temperatureAnnual average temperatureKORA F4PhenoAge accelerationHigh air temperatureGrimAge accelerationHannumAAGrimAAEstimating equationsAging populationHorvathAA
2022
Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4
Ni W, Wolf K, Breitner S, Zhang S, Nikolaou N, Ward-Caviness C, Waldenberger M, Gieger C, Peters A, Schneider A. Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4. Environmental Science And Technology 2022, 56: 17815-17824. PMID: 36442845, PMCID: PMC9775210, DOI: 10.1021/acs.est.2c04486.Peer-Reviewed Original ResearchConceptsLeukocyte telomere lengthAssociated with shorter leukocyte telomere lengthShorter leukocyte telomere lengthKORA F3Cohort studyParticipant's residential addressMeta-analysisShort-term effectsPopulation-based studyPopulation-based settingInterquartile rangeShort-term associationsResidential addressesKORA F4Telomere lengthAge-related morbidityAdult populationPCR-based methodsEffects of air temperatureKORADaily air temperatureQuantitative PCR-based methodCohortParticipantsGeneralized additive model
2021
Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study
Zhang S, Mwiberi S, Pickford R, Breitner S, Huth C, Koenig W, Rathmann W, Herder C, Roden M, Cyrys J, Peters A, Wolf K, Schneider A. Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study. The Lancet Planetary Health 2021, 5: e39-e49. PMID: 33421408, DOI: 10.1016/s2542-5196(20)30275-8.Peer-Reviewed Original ResearchConceptsLong-term air pollution exposureAir pollution exposureAnnual average air pollutant concentrationsAssociation of air pollutionAverage air pollutant concentrationsPollution exposureLongitudinal associationsType 2 diabetesAir pollutant concentrationsLand-use regression modelsAssociated with air pollution exposureExposure to air pollutionCooperative Health ResearchAmbient air pollutionRegression modelsConcentrations of fasting insulinKORA F4German Federal Ministry of EducationHealth researchIQR incrementAir pollutionAnnual rateKORA cohortDevelopment of type 2 diabetesKORA S4
2020
Association of Long-Term Air Pollution with Prevalence and Incidence of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study
Herder C, Schneider A, Zhang S, Wolf K, Maalmi H, Huth C, Pickford R, Laxy M, Bönhof G, Koenig W, Rathmann W, Roden M, Peters A, Thorand B, Ziegler D. Association of Long-Term Air Pollution with Prevalence and Incidence of Distal Sensorimotor Polyneuropathy: KORA F4/FF4 Study. Environmental Health Perspectives 2020, 128: 127013. PMID: 33356516, PMCID: PMC7757787, DOI: 10.1289/ehp7311.Peer-Reviewed Original ResearchConceptsIncident DSPNDistal sensorimotor polyneuropathyAssociated with incident DSPNObese participantsType 2 diabetesNonobese participantsPopulation-based study of older individualsDevelopment of distal sensorimotor polyneuropathyAnnual average air pollutant concentrationsAssociation of air pollutionRates of type 2 diabetesAverage air pollutant concentrationsRobust error varianceCooperative Health ResearchAssociated with higher prevalenceStudies of older individualsPopulation-based studyPoisson regression modelsLong-term air pollutionCross-sectional analysisAir pollutionParticipating residentsKORA F4Health researchYears of age