2024
Heat and Cardiovascular Mortality: An Epidemiological Perspective
Singh N, Areal A, Breitner S, Zhang S, Agewall S, Schikowski T, Schneider A. Heat and Cardiovascular Mortality: An Epidemiological Perspective. Circulation Research 2024, 134: 1098-1112. PMID: 38662866, PMCID: PMC11042530, DOI: 10.1161/circresaha.123.323615.Peer-Reviewed Original ResearchConceptsCardiovascular disease mortalityCardiovascular disease deathsCVD deathHealth professionalsCardiovascular diseaseEpidemiological studiesAssociated with CVD mortalityMeta-analyses of epidemiological studiesEpidemiological evidenceCause-specific deathMiddle-income countriesAll-cause mortalityCVD mortalityLack of evidenceEnvironmental epidemiologyInteractive effects of heatOlder peoplePotential biological pathwaysVulnerable subgroupsSystematic reviewMeta-analysesRobust evidenceHealth effectsPreexisting conditionsHealth
2023
Long-term exposure to ambient air pollution and inflammatory response in the KORA study
Vogli M, Peters A, Wolf K, Thorand B, Herder C, Koenig W, Cyrys J, Maestri E, Marmiroli N, Karrasch S, Zhang S, Pickford R. Long-term exposure to ambient air pollution and inflammatory response in the KORA study. The Science Of The Total Environment 2023, 912: 169416. PMID: 38123091, DOI: 10.1016/j.scitotenv.2023.169416.Peer-Reviewed Original ResearchConceptsLong-term exposure to ambient air pollutionLong-term exposure to air pollutionExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAir pollutionUltrafine particlesParticulate matterIncrease of PM<sLand-use regression modelsAnnual mean concentrationsAtmospheric particulate matterAssociated with increased IL-6Adverse health effectsAssociated with higher concentrationsLand-useMean concentrationsParticipant's home addressPollutionLong-term studiesHealth effectsHigher concentrationsNitrogen oxidesMultiple linear regressionHome addressEffects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study
Ni W, Breitner S, Nikolaou N, Wolf K, Zhang S, Peters A, Herder C, Schneider A. Effects of Short- And Medium-Term Exposures to Lower Air Temperature on 71 Novel Biomarkers of Subclinical Inflammation: Results from the KORA F4 Study. Environmental Science And Technology 2023, 57: 12210-12221. PMID: 37552838, PMCID: PMC10448716, DOI: 10.1021/acs.est.3c00302.Peer-Reviewed Original ResearchConceptsKORA F4 studyBiomarkers of subclinical inflammationHigher risk of chronic diseasesF4 studyLevels of air pollutionLow air temperatureRisk of chronic diseasesPopulation-based KORA F4 studyCross-sectional analysisSubclinical inflammationAdverse health effectsCumulative lagAssociated with higher levelsAir pollutionAir temperatureChronic diseasesNeurotrophin-3Older participantsInterleukin-6Additive modelMedium-term effectsProximity extension assay technologyHealth effectsCardiovascular diseaseHigh risk
2022
Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids.
Tong H, Zhang S, Shen W, Chen H, Salazar C, Schneider A, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals Of The American Thoracic Society 2022, 19: 583-593. PMID: 34797737, DOI: 10.1513/annalsats.202107-767oc.Peer-Reviewed Original ResearchConceptsAmbient air pollutionAir pollutionParticulate matterShort-term exposure to ambient air pollutionShort-term ambient air pollution exposureNational Ambient Air Quality StandardsExposure to ambient air pollutionAmbient Air Quality StandardsHealth effects of air pollutionAmbient air pollution exposureExposure to air pollutionEffects of air pollutionFine particulate matterAir quality standardsAir pollution exposureAssociated with adverse respiratory effectsPollution exposureLevels of ozoneElevated ozone levelsN-3 FA intakePollutionQuality standardsOzone levelsAssociated with ozoneHealth effects
2021
A systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature
Zafeiratou S, Samoli E, Dimakopoulou K, Rodopoulou S, Analitis A, Gasparrini A, Stafoggia M, De' Donato F, Rao S, Monteiro A, Rai M, Zhang S, Breitner S, Aunan K, Schneider A, Katsouyanni K, team E. A systematic review on the association between total and cardiopulmonary mortality/morbidity or cardiovascular risk factors with long-term exposure to increased or decreased ambient temperature. The Science Of The Total Environment 2021, 772: 145383. PMID: 33578152, DOI: 10.1016/j.scitotenv.2021.145383.Peer-Reviewed Original ResearchConceptsHealth outcomesRisk of biasCardiovascular risk factorsSystematic reviewCrude exposure assessmentShort-term mortality displacementDiverse health outcomesAssociation of long-termRisk factorsHigher obesityEffect modificationInadequate adjustmentCardiopulmonary mortalityWorld Health OrganizationEffect modifiersOutcome prevalenceMortality displacementAnnual temperature indicesLong-term exposureAir pollutionCardiovascular mortalityHealthHealth OrganizationHealth effectsRespiratory outcomes