2023
Assessment of short-term heat effects on cardiovascular mortality and vulnerability factors using small area data in Europe
Zhang S, Breitner S, Rai M, Nikolaou N, Stafoggia M, De' Donato F, Samoli E, Zafeiratou S, Katsouyanni K, Rao S, Palomares A, Gasparrini A, Masselot P, Aunan K, Peters A, Schneider A. Assessment of short-term heat effects on cardiovascular mortality and vulnerability factors using small area data in Europe. Environment International 2023, 179: 108154. PMID: 37603993, DOI: 10.1016/j.envint.2023.108154.Peer-Reviewed Original ResearchConceptsCardiovascular disease mortalityCardiovascular disease deathsRelative riskCardiovascular diseaseRandom-effects meta-analysisSmall area levelPooled relative riskShort-term associationsQuasi-Poisson regressionArea-specific estimatesLevels of fine particulate matterSmall area dataRural settingsIdentifying individual-Vulnerability factorsMeta-regressionCardiovascular mortalityRural areasDegree of urbanizationMeta-analysisFine particulate matterSubgroup analysisEuropean countriesIndividual-Potential vulnerability factors
2022
Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers
Chen H, Zhang S, Yu B, Xu Y, Rappold A, Diaz-Sanchez D, Samet J, Tong H. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. Ecotoxicology And Environmental Safety 2022, 239: 113604. PMID: 35576800, PMCID: PMC9167781, DOI: 10.1016/j.ecoenv.2022.113604.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionAmbient air pollutionExposure to air pollutionAir pollutionShort-term exposure to ambient PM<sub>2.5</sub> waExposure to ambient PM<sub>2.5</sub>Short-term exposure to ambient fine particulate matterShort-term exposure to ambient air pollutionAmbient PM<sub>2.5</sub>Exposure to ambient fine particulate matterAmbient fine particulate matterEffects of exposure to air pollutionAir quality monitoring stationsEffects of air pollution exposureFine particulate matterQuality monitoring stationsAir pollutant concentrationsResearch Triangle area of North CarolinaAir pollution exposureTriangle area of North CarolinaBlood lipid biomarkersResearch Triangle areaPollutant concentrationsParticulate matterPollution exposureLung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids.
Tong H, Zhang S, Shen W, Chen H, Salazar C, Schneider A, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals Of The American Thoracic Society 2022, 19: 583-593. PMID: 34797737, DOI: 10.1513/annalsats.202107-767oc.Peer-Reviewed Original ResearchConceptsAmbient air pollutionAir pollutionParticulate matterShort-term exposure to ambient air pollutionShort-term ambient air pollution exposureNational Ambient Air Quality StandardsExposure to ambient air pollutionAmbient Air Quality StandardsHealth effects of air pollutionAmbient air pollution exposureExposure to air pollutionEffects of air pollutionFine particulate matterAir quality standardsAir pollution exposureAssociated with adverse respiratory effectsPollution exposureLevels of ozoneElevated ozone levelsN-3 FA intakePollutionQuality standardsOzone levelsAssociated with ozoneHealth effectsOmega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution. Particle And Fibre Toxicology 2022, 19: 12. PMID: 35139860, PMCID: PMC8826673, DOI: 10.1186/s12989-022-00451-4.Peer-Reviewed Original ResearchConceptsExposure to PM2.5Air pollutionEffects of exposure to fine particulate matterShort-term exposure to PM2.5National Ambient Air Quality StandardsU.S. National Ambient Air Quality StandardsExposure to fine particulate matterConcentrations of ambient PM2.5Air quality monitoring stationsAmbient Air Quality StandardsFine particulate matterAir pollutant concentrationsAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaAmbient air pollutionResultsThe average concentrationTriangle area of North CarolinaResearch Triangle areaAmbient PM2.5Daily PM2.5Pollutant concentrationsParticulate matterPM2.5Monitoring stations
2021
The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults
Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J, Tong H. The influence of dietary intake of omega-3 polyunsaturated fatty acids on the association between short-term exposure to ambient nitrogen dioxide and respiratory and cardiovascular outcomes among healthy adults. Environmental Health 2021, 20: 123. PMID: 34872587, PMCID: PMC8650256, DOI: 10.1186/s12940-021-00809-9.Peer-Reviewed Original ResearchConceptsNational Ambient Air Quality StandardsExposure to ambient nitrogen dioxideOmega-3 groupAmbient nitrogen dioxideOmega-3 PUFA intakeOmega-3 polyunsaturated fatty acidsHeart rate variabilityBlood lipidsAmbient NO2NO2 concentrationsVascular functionLung functionExposure to fine particulate matterAir quality monitoring stationsConcentrations of ambient NO2Interquartile rangeAmbient Air Quality StandardsNitrogen dioxideShort-term exposure to NO2PUFA intakeCardiovascular outcomesFine particulate matterAir quality standardsQuality monitoring stationsResearch Triangle area of North CarolinaAssociation between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Ward-Caviness C, Diaz-Sanchez D, Kraus W, Hauser E, Schwartz J, Peters A, Schneider A. Association between short-term exposure to ambient fine particulate matter and myocardial injury in the CATHGEN cohort. Environmental Pollution 2021, 275: 116663. PMID: 33581627, DOI: 10.1016/j.envpol.2021.116663.Peer-Reviewed Original ResearchConceptsFine particulate matterParticulate matterDaily PM<sub>2.5</sub> concentrationsShort-term exposure to ambient fine particulate matterAcute PM<sub>2.5</sub> exposureAssociation of PM<sub>2.5</sub> wiElevated PM<sub>2.5</sub>Exposure to ambient fine particulate matterExposure to fine particulate matterAmbient fine particulate matterParticipant's residential addressCTnT testNeural network-based hybrid modelResidential addressesElevated indicatorsMeasurement of NT-pro-BNPConcentrationMatterMyocardial infarction symptomsDuke University HospitalInfarction symptomsRural areasOdds ratioCoronary eventsInterquartile range
2020
Short-term Exposure to Fine Particulate Matter and Myocardial Injury among Patients Undergoing Cardiac Catheterization
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Ward-Caviness C, Diaz-Sanchez D, Kraus W, Hauser E, Schwartz J, Peters A, Schneider A. Short-term Exposure to Fine Particulate Matter and Myocardial Injury among Patients Undergoing Cardiac Catheterization. ISEE Conference Abstracts 2020, 2020 DOI: 10.1289/isee.2020.virtual.o-os-486.Peer-Reviewed Original ResearchShort-term exposure to fine particulate matterExposure to fine particulate matterFine particulate matter
2018
Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Diaz-Sanchez D, Kraus W, Schwartz J, Hauser E, Peters A, Schneider A. Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization. Particle And Fibre Toxicology 2018, 15: 38. PMID: 30305173, PMCID: PMC6180522, DOI: 10.1186/s12989-018-0275-z.Peer-Reviewed Original ResearchConceptsAssociations of PM2.5Particulate matterAir pollutionShort-term exposure to air pollutionDaily concentrations of PM2.5Short-term effects of particulate matterEffects of fine particulate matterShort-term effects of fine particulate matterExposure to air pollutionEffects of particulate matterConcentrations of PM2.5Fine particulate matterPollution-induced changesAir pollution effectsInvestigate short-term effectsDaily concentrationsPM2.5Pollution effectsAssociation of O3Temporal lag structureAerodynamic diameterDistributed-lag modelParticipant's home addressExposure modelO3