2024
Heat and Cardiovascular Mortality: An Epidemiological Perspective
Singh N, Areal A, Breitner S, Zhang S, Agewall S, Schikowski T, Schneider A. Heat and Cardiovascular Mortality: An Epidemiological Perspective. Circulation Research 2024, 134: 1098-1112. PMID: 38662866, PMCID: PMC11042530, DOI: 10.1161/circresaha.123.323615.Peer-Reviewed Original ResearchConceptsCardiovascular disease mortalityCardiovascular disease deathsCVD deathHealth professionalsCardiovascular diseaseEpidemiological studiesAssociated with CVD mortalityMeta-analyses of epidemiological studiesEpidemiological evidenceCause-specific deathMiddle-income countriesAll-cause mortalityCVD mortalityLack of evidenceEnvironmental epidemiologyInteractive effects of heatOlder peoplePotential biological pathwaysVulnerable subgroupsSystematic reviewMeta-analysesRobust evidenceHealth effectsPreexisting conditionsHealth
2022
Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis
Zhang S, Breitner S, Pickford R, Lanki T, Okokon E, Morawska L, Samoli E, Rodopoulou S, Stafoggia M, Renzi M, Schikowski T, Zhao Q, Schneider A, Peters A. Short-term effects of ultrafine particles on heart rate variability: A systematic review and meta-analysis. Environmental Pollution 2022, 314: 120245. PMID: 36162563, DOI: 10.1016/j.envpol.2022.120245.Peer-Reviewed Original ResearchConceptsShort-term effects of ultrafine particlesMeta-analysisHeart rate variabilitySystematic reviewEffects of ultrafine particlesSynthesized effect estimatesShort-term effectsSingle-pollutant modelsStudy systematically reviewsRisk of biasMeta-analyzed studiesAssociated with decreased HRVNormal-to-normal intervalsRandom-effects modelR-R interval differencesWeb of ScienceOutcome measuresEffect estimatesPooled estimatesRate variabilityExposure to ambient ultrafine particlesEpidemiological studiesMeta-analyzedRatio of low-frequency to high-frequency powerCardiovascular disease