2023
Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration
Ni W, Nikolaou N, Ward-Caviness C, Breitner S, Wolf K, Zhang S, Wilson R, Waldenberger M, Peters A, Schneider A. Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration. Environment International 2023, 178: 108109. PMID: 37517177, PMCID: PMC10656697, DOI: 10.1016/j.envint.2023.108109.Peer-Reviewed Original ResearchConceptsEpigenetic age accelerationGeneralized estimating equationsExposure to high air temperaturesAge accelerationAverage air temperatureDistributed lag non-linear modelMeasures of epigenetic age accelerationAir temperatureHuman health worldwideExposure to air temperaturesSpatial variationClimate changeEffects of air temperatureAnnual average temperatureKORA F4PhenoAge accelerationHigh air temperatureGrimAge accelerationHannumAAGrimAAEstimating equationsAging populationHorvathAA
2022
Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4
Ni W, Wolf K, Breitner S, Zhang S, Nikolaou N, Ward-Caviness C, Waldenberger M, Gieger C, Peters A, Schneider A. Higher Daily Air Temperature Is Associated with Shorter Leukocyte Telomere Length: KORA F3 and KORA F4. Environmental Science And Technology 2022, 56: 17815-17824. PMID: 36442845, PMCID: PMC9775210, DOI: 10.1021/acs.est.2c04486.Peer-Reviewed Original ResearchConceptsLeukocyte telomere lengthAssociated with shorter leukocyte telomere lengthShorter leukocyte telomere lengthKORA F3Cohort studyParticipant's residential addressMeta-analysisShort-term effectsPopulation-based studyPopulation-based settingInterquartile rangeShort-term associationsResidential addressesKORA F4Telomere lengthAge-related morbidityAdult populationPCR-based methodsEffects of air temperatureKORADaily air temperatureQuantitative PCR-based methodCohortParticipantsGeneralized additive model