2008
Cross-talk between estrogen and leptin signaling in the hypothalamus
Gao Q, Horvath TL. Cross-talk between estrogen and leptin signaling in the hypothalamus. AJP Endocrinology And Metabolism 2008, 294: e817-e826. PMID: 18334610, DOI: 10.1152/ajpendo.00733.2007.Peer-Reviewed Original ResearchConceptsAdipocyte-secreted hormone leptinGonadal steroid hormone estrogenAction of leptinMajor risk factorNeuroendocrine reproductive axisEnergy expenditureHalf of adultsSteroid hormone estrogenEnhanced food intakeFunction of estrogenEstrogen deficiencyRisk factorsHormone leptinCardiovascular diseaseHormone estrogenFood intakeBody fatReproductive axisLeptinEstrogenRegulation of reproductionEnergy homeostasisWeight gainEstrogen facilitatesNeuroendocrine processes
2005
Cannabinoids, opioids and eating behavior: The molecular face of hedonism?
Cota D, Tschöp MH, Horvath TL, Levine AS. Cannabinoids, opioids and eating behavior: The molecular face of hedonism? Brain Research Reviews 2005, 51: 85-107. PMID: 16364446, DOI: 10.1016/j.brainresrev.2005.10.004.Peer-Reviewed Original ResearchConceptsOpioid receptor antagonistPrevalence of obesityAnti-obesity drugsAnti-obesity therapiesCentral nervous mechanismsAddictive componentOpioid systemReceptor antagonistEnergy balance controlFood intakeNervous mechanismsAddictive propertiesEnergy homeostasisHealth threatLife expectancyBody of dataRewarding valueAlarming increaseObesityBalance controlHomeostatic componentWestern countriesFunctional interactionHedonic aspectsOpioids