Welcome to the Horvath Lab!

Our main interest is the neuroendocrine regulation of homeostasis with particular emphasis on metabolic disorders, such as obesity and diabetes, and the effect of metabolic signals on higher brain functions and neurodegeneration. We have active research programs to pursue the role of synaptic plasticity in the mediation of peripheral hormones’ effects on the central nervous system. 

We also study the role of mitochondrial membrane potential in normal and pathological brain functions with particular emphasis on the acute effect of mitochondria in neuronal transmission and neuroprotection. We combine classical neurobiological approaches, including electrophysiology and neuroanatomy, with endocrine and genetic techniques to better understand biological events at the level of the organism.

Research Interests

  • Neurobiology of obesity 
  • Neuroendocrine physiology

Principal Investigator

Tamas Horvath, DVM, PhD

Jean and David W. Wallace Professor of Comparative Medicine and Professor of Neuroscience and of Obstetrics, Gynecology, and Reproductive Sciences

Contact Info
Horvath Lab
Brady Memorial Laboratory
310 Cedar Street
New Haven, CT 06510
Academic Office
Brady Memorial Laboratory
310 Cedar Street
New Haven, CT 06510
Surrealist interpretation of appetite regulation

Pop-surrealist interpretation of appetite and body weight regulation in hypothalamic orexigenic AgRP and anorexigenic POMC neurons via mitochondrial dynamics and mitochondria-ER interactions.