Publications

• Complement factor H in molecular regulation of angiogenesis.Li J, Wang K, Starodubtseva MN, Nadyrov E, Kapron CM, Hoh J, Liu J. Med Rev (2021). 2024 Oct; 2024 Jul 1. PMID: 39444793.
• Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds.Li Z, Wang Z, Chen Z, Voegeli H, Lichtman JH, Smith P, Liu J, DeWan AT, Hoh J. BMC Genomics. 2023 Jun 5; 2023 Jun 5. PMID: 37277710.
• Müller cells in pathological retinal angiogenesis.Li X, Liu J, Hoh J, Liu J. Transl Res. 2019 May; 2018 Dec 27. PMID: 30639368.
• Cadmium Induces Glomerular Endothelial Cell-Specific Expression of Complement Factor H via the -1635 AP-1 Binding Site.Chen X, Li L, Liu F, Hoh J, Kapron CM, Liu J. J Immunol. 2019 Feb 15; 2019 Jan 14. PMID: 30642982.
• BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia.de Smith AJ, Walsh KM, Francis SS, Zhang C, Hansen HM, Smirnov I, Morimoto L, Whitehead TP, Kang A, Shao X, Barcellos LF, McKean-Cowdin R, Zhang L, Fu C, Wang R, Yu H, Hoh J, Dewan AT, Metayer C, Ma X, Wiemels JL. Int J Cancer. 2018 Dec 1; 2018 Oct 3. PMID: 29923177.
• Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1.Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Hypertension. 2018 Aug; 2018 Jul 2. PMID: 29967039.
• GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X. Nat Commun. 2018 Jan 18; 2018 Jan 18. PMID: 29348612.
• Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration.Liu J, Hoh J. J Cancer. 2017; 2017 Jul 15. PMID: 28819420.
• Genetic predisposition to elevated levels of C-reactive protein is associated with a decreased risk for preeclampsia.Spracklen CN, Smith CJ, Saftlas AF, Triche EW, Bjonnes A, Keating BJ, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Hypertens Pregnancy. 2017 Feb; 2016 Sep 22. PMID: 27657194.
• A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging.Patterson VL, Thompson BS, Cherry C, Wang SB, Chen B, Hoh J. J Vis Exp. 2016 Jul 14; 2016 Jul 14. PMID: 27500671.
• 2016: A 'Mitochondria' Odyssey.Cherry C, Thompson B, Saptarshi N, Wu J, Hoh J. Trends Mol Med. 2016 May; 2016 Apr 14. PMID: 27151392.
• Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia.Smith CJ, Saftlas AF, Spracklen CN, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Am J Hypertens. 2016 Jan; 2015 May 23. PMID: 26002928.
• Generation and characterization of mice with a conditional null allele of the HtrA4 gene.Liu J, Li Y, Hoh J. Mol Med Rep. 2015 Nov; 2015 Sep 3. PMID: 26353049.
• Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia.Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Am J Hypertens. 2015 Jul; 2014 Dec 17. PMID: 25523295.
• Loss of HtrA1-induced attenuation of TGF-β signaling in fibroblasts might not be the main mechanism of CARASIL pathogenesis.Liu J, Dong F, Hoh J. Proc Natl Acad Sci U S A. 2015 Apr 7; 2015 Mar 13. PMID: 25770224.
• Postnatal overexpression of the human ARMS2 gene does not induce abnormalities in retina and choroid in transgenic mouse models.Liu J, Hoh J. Invest Ophthalmol Vis Sci. 2015 Feb 25; 2015 Feb 25. PMID: 25717153.
• Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.Patterson VL, Zullo AJ, Koenig C, Stoessel S, Jo H, Liu X, Han J, Choi M, DeWan AT, Thomas JL, Kuan CY, Hoh J. PLoS One. 2014; 2014 Dec 22. PMID: 25531304.
• Protoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine protease.Jo H, Patterson V, Stoessel S, Kuan CY, Hoh J. PLoS One. 2014; 2014 Dec 15. PMID: 25506911.
• Genome-wide association study identifies a maternal copy-number deletion in PSG11 enriched among preeclampsia patients.Zhao L, Triche EW, Walsh KM, Bracken MB, Saftlas AF, Hoh J, Dewan AT. BMC Pregnancy Childbirth. 2012 Jun 29; 2012 Jun 29. PMID: 22748001.
• Disease risk prediction with rare and common variants.Wu C, Walsh KM, Dewan AT, Hoh J, Wang Z. BMC Proc. 2011 Nov 29; 2011 Nov 29. PMID: 22373337.
• A comparison of association methods correcting for population stratification in case-control studies.Wu C, DeWan A, Hoh J, Wang Z. Ann Hum Genet. 2011 May; 2011 Jan 31. PMID: 21281271.
• A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.Walsh KM, Choi M, Oberg K, Kulke MH, Yao JC, Wu C, Jurkiewicz M, Hsu LI, Hooshmand SM, Hassan M, Janson ET, Cunningham JL, Vosburgh E, Sackler RS, Lifton RP, Dewan AT, Hoh J. Endocr Relat Cancer. 2011 Feb; 2011 Jan 13. PMID: 21139019.
• Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism.Walsh KM, Bracken MB, Murk WK, Hoh J, Dewan AT. Mutat Res. 2010 Aug 7; 2010 May 27. PMID: 20553737.
• CCR3: Shedding new light on a dark problem?Mason AB, Hoh J. J Mol Cell Biol. 2009 Oct; 2009 Aug 14. PMID: 19684049.
• Detecting essential and removable interactions in genome-wide association studies.Wu C, Zhang H, Liu X, Dewan A, Dubrow R, Ying Z, Yang Y, Hoh J. Stat Interface. 2009 Jan 1. PMID: 21165165.
• The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.Zhang H, Morrison MA, Dewan A, Adams S, Andreoli M, Huynh N, Regan M, Brown A, Miller JW, Kim IK, Hoh J, Deangelis MM. BMC Med Genet. 2008 Jun 9; 2008 Jun 9. PMID: 18541031.
• Two genetic pathways for age-related macular degeneration.DeWan A, Bracken MB, Hoh J. Curr Opin Genet Dev. 2007 Jun; 2007 Apr 27. PMID: 17467263.
• Linkage disequilibrium mapping for complex disease genes.DeWan A, Klein RJ, Hoh J. Methods Mol Biol. 2007. PMID: 17984540.
• HTRA1 promoter polymorphism in wet age-related macular degeneration.Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J. Science. 2006 Nov 10; 2006 Oct 19. PMID: 17053108.
• Genetic dissection of diseases: design and methods.Hoh J, Ott J. Curr Opin Genet Dev. 2004 Jun. PMID: 15172663.