Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function
Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo e Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N. Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function. Nature Medicine 2017, 24: 39-49. PMID: 29200204, PMCID: PMC5760280, DOI: 10.1038/nm.4447.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedEpitheliumFemaleHumansIodide PeroxidaseMiceMice, Inbred C57BLMice, KnockoutMitochondriaMolecular MimicryPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaProtein KinasesPulmonary FibrosisThyroid Hormones