Publications

• The effect of adrenalectomy on bleomycin-induced pulmonary fibrosis in mice.McGovern J, Perry C, Ghincea A, Herzog EL, Shao S, Sun H. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 1; 2024 Oct 29. PMID: 39470613.
• Positron emission tomography an imaging biomarker in pulmonary fibrosis: from therapeutic mechanism to treatment monitoring.Cho SG, Herzog EL, Thorn SL, Sinusas AJ. EBioMedicine. 2024 Dec 18; 2024 Dec 18. PMID: 39700895.
• Proteolysis and Contractility Regulate Tissue Opening and Wound Healing by Lung Fibroblasts in 3D Microenvironments.Xiao H, Sylla K, Gong X, Wilkowski B, Rossello-Martinez A, Jordan SN, Mintah EY, Zheng A, Sun H, Herzog EL, Mak M. Adv Healthc Mater. 2024 Dec; 2024 Jul 5. PMID: 38967294.
• Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts.Sand JMB, Jessen H, Leeming DJ, Yu S, Lee CJ, Hu B, Sun Y, Adams T, Pivarnik T, Liu A, Woo S, McGovern JR, Fiorini V, Saber T, Higuero-Sevilla JP, Gulati M, Kaminski N, Damsky W, Shaw AC, Mohanty S, Goobie G, Zhang Y, Herzog EL, Ryu C. Thorax. 2024 Nov 14; 2024 Nov 14. PMID: 39117421.
• Retraction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cortez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Life Sci Alliance. 2024 Nov; 2024 Aug 29. PMID: 39209538.
• A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis.Ishikawa G, Peng X, McGovern J, Ghincea A, Woo S, Okuno D, Yu S, Lee CJ, Liu A, Saber T, Hu B, Sun Y, Sun H, Jumaily KA, Feghali-Bostwick C, Sumida TS, Sauler M, Ryu C, Herzog EL. bioRxiv. 2024 Sep 9; 2024 Sep 9. PMID: 39314391.
• Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis.Trujillo G, Regueiro-Ren A, Liu C, Hu B, Sun Y, Ahangari F, Fiorini V, Ishikawa G, Al Jumaily K, Khoury J, McGovern J, Lee CJ, Peng XY, Pivarnik T, Sun H, Walia A, Woo S, Yu S, Antin-Ozerkis DE, Sauler M, Kaminski N, Herzog EL, Ryu C. Am J Respir Crit Care Med. 2024 Aug 27; 2024 Aug 27. PMID: 39189851.
• Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis.Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya JD, Dela Cruz CS, Herzog EL, Kaminski N. Am J Respir Crit Care Med. 2024 Aug 15. PMID: 38717443.
• Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection.Kim J, Yuan Y, Agaronyan K, Zhao A, D Wang V, Gupta G, Essayas H, Kaminski A, McGovern J, Yu S, Woo S, Lee CJ, Gandhi S, Saber T, Saleh T, Hu B, Sun Y, Ishikawa G, Bain W, Evankovich J, Chen L, Yun H, Herzog EL, Dela Cruz CS, Ryu C, Sharma L. bioRxiv. 2024 Aug 12; 2024 Aug 12. PMID: 38496452.
• Nuclear-penetrating scleroderma autoantibody inhibits topoisomerase 1 cleavage complex formation.May CK, Noble PW, Herzog EL, Meffre E, Hansen JE. Biochem Biophys Res Commun. 2024 Aug 6; 2024 May 14. PMID: 38759301.
• Circulating Mitochondrial DNA Is Associated With High Levels of Fatigue in Two Independent Sarcoidosis Cohorts.Fiorini V, Hu B, Sun Y, Yu S, McGovern J, Gandhi S, Woo S, Turcotte-Foster SJ, Pivarnik T, Khan Z, Adams T, Herzog EL, Kaminski N, Gulati M, Ryu C. Chest. 2024 May; 2023 Nov 15. PMID: 37977267.
• TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E. J Exp Med. 2023 Dec 4; 2023 Sep 29. PMID: 37773045.
• Mitochondrial DNA Sensing Pathogen Recognition Receptors in Systemic Sclerosis Associated Interstitial Lung Disease: A Review.Ghincea A, Woo S, Yu S, Pivarnik T, Fiorini V, Herzog EL, Ryu C. Curr Treatm Opt Rheumatol. 2023 Dec; 2023 Aug 8. PMID: 38230363.
• Correction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Life Sci Alliance. 2023 May; 2023 Apr 10. PMID: 37037591.
• α1 Adrenoreceptor antagonism mitigates extracellular mitochondrial DNA accumulation in lung fibrosis models and in patients with idiopathic pulmonary fibrosis.Ishikawa G, Peng X, McGovern J, Woo S, Perry C, Liu A, Yu S, Ghincea A, Kishchanka A, Fiorini V, Hu B, Sun Y, Sun H, Ryu C, Herzog EL. Am J Physiol Lung Cell Mol Physiol. 2023 May 1; 2023 Jan 17. PMID: 36648147.
• Single-cell profiling reveals immune aberrations in progressive idiopathic pulmonary fibrosis.Unterman A, Zhao AY, Neumark N, Schupp JC, Ahangari F, Cosme C Jr, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida TS, Gomez JL, Herazo-Maya J, Dela Cruz CS, Herzog EL, Kaminski N. medRxiv. 2023 Apr 29; 2023 Apr 29. PMID: 37163015.
• Rational engineering of lung alveolar epithelium.Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE. NPJ Regen Med. 2023 Apr 28; 2023 Apr 28. PMID: 37117221.
• Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants.Mlakar L, Garrett SM, Watanabe T, Sanderson M, Nishimoto T, Heywood J, Helke KL, Pilewski JM, Herzog EL, Feghali-Bostwick C. Biomedicines. 2022 Nov 9; 2022 Nov 9. PMID: 36359382.
• PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a "Complement".Ishikawa G, Herzog EL. Am J Respir Crit Care Med. 2022 Nov 1. PMID: 35820078.
• Impact of Sex and Gender on Autoimmune Lung Disease: Opportunities for Future Research: NHLBI Working Group Report.Volkmann ER, Siegfried J, Lahm T, Ventetuolo CE, Mathai SC, Steen V, Herzog EL, Shansky R, Anguera MC, Danoff SK, Giles JT, Lee YC, Drake W, Maier LA, Lachowicz-Scroggins M, Park H, Banerjee K, Fessel J, Reineck L, Vuga L, Crouser E, Feghali-Bostwick C. Am J Respir Crit Care Med. 2022 Oct 1. PMID: 35549658.
• Stem cells, cell therapies, and bioengineering in lung biology and disease 2021.Ikonomou L, Magnusson M, Dries R, Herzog EL, Hynds RE, Borok Z, Park JA, Skolasinski S, Burgess JK, Turner L, Mojarad SM, Mahoney JE, Lynch T, Lehmann M, Thannickal VJ, Hook JL, Vaughan AE, Hoffman ET, Weiss DJ, Ryan AL. Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1; 2022 Jun 28. PMID: 35762622.
• Kasugamycin Is a Novel Chitinase 1 Inhibitor with Strong Antifibrotic Effects on Pulmonary Fibrosis.Lee JH, Lee CM, Lee JH, Kim MO, Park JW, Kamle S, Akosman B, Herzog EL, Peng XY, Elias JA, Lee CG. Am J Respir Cell Mol Biol. 2022 Sep. PMID: 35679109.
• Occupational and environmental exposures in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) study.Ryan SM, Mroz MM, Herzog EL, Ryu C, Fingerlin TE, Maier LA, Gulati M. Respir Med. 2022 Aug-Sep; 2022 Jun 30. PMID: 35932543.
• Emerging insights in sarcoidosis: moving forward through reverse translational research.Liu A, Sharma L, Yan X, Dela Cruz CS, Herzog EL, Ryu C. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 1; 2022 Feb 23. PMID: 35196896.
• An Acute Exacerbation of Idiopathic Pulmonary Fibrosis After BNT162b2 mRNA COVID-19 Vaccination: A Case Report.Ghincea A, Ryu C, Herzog EL. Chest. 2022 Feb. PMID: 35131075.
• Defective Early B Cell Tolerance Checkpoints in Patients With Systemic Sclerosis Allow the Production of Self Antigen-Specific Clones.Glauzy S, Olson B, May CK, Parisi D, Massad C, Hansen JE, Ryu C, Herzog EL, Meffre E. Arthritis Rheumatol. 2022 Feb; 2021 Dec 16. PMID: 34279059.
• Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis.Chandran RR, Xie Y, Gallardo-Vara E, Adams T, Garcia-Milian R, Kabir I, Sheikh AQ, Kaminski N, Martin KA, Herzog EL, Greif DM. Nat Commun. 2021 Dec 10; 2021 Dec 10. PMID: 34893592.
• Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis.Vukmirovic M, Yan X, Gibson KF, Gulati M, Schupp JC, DeIuliis G, Adams TS, Hu B, Mihaljinec A, Woolard TN, Lynn H, Emeagwali N, Herzog EL, Chen ES, Morris A, Leader JK, Zhang Y, Garcia JGN, Maier LA, Collman RG, Drake WP, Becich MJ, Hochheiser H, Wisniewski SR, Benos PV, Moller DR, Prasse A, Koth LL, Kaminski N. Eur Respir J. 2021 Dec; 2021 Dec 2. PMID: 34083402.
• Integrated computational and experimental pipeline for quantifying local cell-matrix interactions.Xiao H, Nguyen RY, LaRanger R, Herzog EL, Mak M. Sci Rep. 2021 Aug 12; 2021 Aug 12. PMID: 34385554.
• Evolving Perspectives on Innate Immune Mechanisms of IPF.Ishikawa G, Liu A, Herzog EL. Front Mol Biosci. 2021; 2021 Aug 9. PMID: 34434962.
• Fibroblasts: Origins, definitions, and functions in health and disease.Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V. Cell. 2021 Jul 22. PMID: 34297930.
• Molecular Markers and the Promise of Precision Medicine for Interstitial Lung Disease.Newton CA, Herzog EL. Clin Chest Med. 2021 Jun. PMID: 34024410.
• Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes.Minasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1; 2021 Apr 14. PMID: 33851886.
• Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension.Ntokou A, Dave JM, Kauffman AC, Sauler M, Ryu C, Hwa J, Herzog EL, Singh I, Saltzman WM, Greif DM. JCI Insight. 2021 Mar 22; 2021 Mar 22. PMID: 33591958.
• A Clinic Blueprint for Post-Coronavirus Disease 2019 RECOVERY: Learning From the Past, Looking to the Future.Lutchmansingh DD, Knauert MP, Antin-Ozerkis DE, Chupp G, Cohn L, Dela Cruz CS, Ferrante LE, Herzog EL, Koff J, Rochester CL, Ryu C, Singh I, Tickoo M, Winks V, Gulati M, Possick JD. Chest. 2021 Mar; 2020 Nov 4. PMID: 33159907.
• Gene coexpression networks reveal novel molecular endotypes in alpha-1 antitrypsin deficiency.Chu JH, Zang W, Vukmirovic M, Yan X, Adams T, DeIuliis G, Hu B, Mihaljinec A, Schupp JC, Becich MJ, Hochheiser H, Gibson KF, Chen ES, Morris A, Leader JK, Wisniewski SR, Zhang Y, Sciurba FC, Collman RG, Sandhaus R, Herzog EL, Patterson KC, Sauler M, Strange C, Kaminski N. Thorax. 2021 Feb; 2020 Dec 10. PMID: 33303696.
• Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. J Clin Invest. 2021 Jan 4. PMID: 33393489.
• Bioactive Plasma Mitochondrial DNA Is Associated With Disease Progression in Scleroderma-Associated Interstitial Lung Disease.Ryu C, Walia A, Ortiz V, Perry C, Woo S, Reeves BC, Sun H, Winkler J, Kanyo JE, Wang W, Vukmirovic M, Ristic N, Stratton EA, Meena SR, Minasyan M, Kurbanov D, Liu X, Lam TT, Farina G, Gomez JL, Gulati M, Herzog EL. Arthritis Rheumatol. 2020 Nov; 2020 Oct 8. PMID: 32602227.
• Reduced Sialylation and Bioactivity of the Antifibrotic Protein Serum Amyloid P in the Sera of Patients with Idiopathic Pulmonary Fibrosis.Chen W, Karhadkar TR, Ryu C, Herzog EL, Gomer RH. Immunohorizons. 2020 Jun 23; 2020 Jun 23. PMID: 32576593.
• GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis.Zhang Y, Jiang M, Nouraie M, Roth MG, Tabib T, Winters S, Chen X, Sembrat J, Chu Y, Cardenes N, Tuder RM, Herzog EL, Ryu C, Rojas M, Lafyatis R, Gibson KF, McDyer JF, Kass DJ, Alder JK. Am J Physiol Lung Cell Mol Physiol. 2019 Oct 1; 2019 Aug 21. PMID: 31432710.
• Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis.Ryu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL. Eur Respir J. 2019 Aug; 2019 Aug 29. PMID: 31273041.
• GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance.Luan HH, Wang A, Hilliard BK, Carvalho F, Rosen CE, Ahasic AM, Herzog EL, Kang I, Pisani MA, Yu S, Zhang C, Ring AM, Young LH, Medzhitov R. Cell. 2019 Aug 22; 2019 Aug 8. PMID: 31402172.
• Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Life Sci Alliance. 2019 Jun; 2019 May 13. PMID: 31085559.
• LMO7 Is a Negative Feedback Regulator of Transforming Growth Factor β Signaling and Fibrosis.Xie Y, Ostriker AC, Jin Y, Hu H, Sizer AJ, Peng G, Morris AH, Ryu C, Herzog EL, Kyriakides T, Zhao H, Dardik A, Yu J, Hwa J, Martin KA. Circulation. 2019 Jan 29. PMID: 30586711.
• S100A12 as a marker of worse cardiac output and mortality in pulmonary hypertension.Tzouvelekis A, Herazo-Maya JD, Ryu C, Chu JH, Zhang Y, Gibson KF, Adonteng-Boateng PK, Li Q, Pan H, Cherry B, Ahmad F, Ford HJ, Herzog EL, Kaminski N, Fares WH. Respirology. 2018 Aug; 2018 Apr 2. PMID: 29611244.
• Semaphorin 7A in circulating regulatory T cells is increased in autosomal-dominant polycystic kidney disease and decreases with tolvaptan treatment.Lee Y, Blount KL, Dai F, Thompson S, Scher JK, Bitterman S, Droher M, Herzog EL, Moeckel G, Karihaloo A, Dahl NK. Clin Exp Nephrol. 2018 Aug; 2018 Feb 16. PMID: 29453607.
• A rare presentation of pulmonary sarcoidosis as a solitary lung mass: a case report.Kelleher DW, Yaggi M, Homer R, Herzog EL, Ryu C. J Med Case Rep. 2018 Apr 13; 2018 Apr 13. PMID: 29650028.
• The Role of Immune and Inflammatory Cells in Idiopathic Pulmonary Fibrosis.Desai O, Winkler J, Minasyan M, Herzog EL. Front Med (Lausanne). 2018; 2018 Mar 20. PMID: 29616220.
• Myeloid-derived Suppressor Cells Are Necessary for Development of Pulmonary Hypertension.Bryant AJ, Shenoy V, Fu C, Marek G, Lorentsen KJ, Herzog EL, Brantly ML, Avram D, Scott EW. Am J Respir Cell Mol Biol. 2018 Feb. PMID: 28862882.
• Pulmonary arterial hypertension in the setting of scleroderma is different than in the setting of lupus: A review.Bazan IS, Mensah KA, Rudkovskaia AA, Adonteng-Boateng PK, Herzog EL, Buckley L, Fares WH. Respir Med. 2018 Jan; 2017 Dec 2. PMID: 29413506.
• Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo E Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N. Nat Med. 2018 Jan; 2017 Dec 4. PMID: 29200204.
• Human pericytes adopt myofibroblast properties in the microenvironment of the IPF lung.Sava P, Ramanathan A, Dobronyi A, Peng X, Sun H, Ledesma-Mendoza A, Herzog EL, Gonzalez AL. JCI Insight. 2017 Dec 21; 2017 Dec 21. PMID: 29263297.
• Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis.Ryu C, Sun H, Gulati M, Herazo-Maya JD, Chen Y, Osafo-Addo A, Brandsdorfer C, Winkler J, Blaul C, Faunce J, Pan H, Woolard T, Tzouvelekis A, Antin-Ozerkis DE, Puchalski JT, Slade M, Gonzalez AL, Bogenhagen DF, Kirillov V, Feghali-Bostwick C, Gibson K, Lindell K, Herzog RI, Dela Cruz CS, Mehal W, Kaminski N, Herzog EL, Trujillo G. Am J Respir Crit Care Med. 2017 Dec 15. PMID: 28783377.
• Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study.Herazo-Maya JD, Sun J, Molyneaux PL, Li Q, Villalba JA, Tzouvelekis A, Lynn H, Juan-Guardela BM, Risquez C, Osorio JC, Yan X, Michel G, Aurelien N, Lindell KO, Klesen MJ, Moffatt MF, Cookson WO, Zhang Y, Garcia JGN, Noth I, Prasse A, Bar-Joseph Z, Gibson KF, Zhao H, Herzog EL, Rosas IO, Maher TM, Kaminski N. Lancet Respir Med. 2017 Nov; 2017 Sep 21. PMID: 28942086.
• CCL2 and T cells in pulmonary fibrosis: an old player gets a new role.Osafo-Addo AD, Herzog EL. Thorax. 2017 Nov; 2017 Sep 7. PMID: 28883089.
• Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis.Murray LA, Habiel DM, Hohmann M, Camelo A, Shang H, Zhou Y, Coelho AL, Peng X, Gulati M, Crestani B, Sleeman MA, Mustelin T, Moore MW, Ryu C, Osafo-Addo AD, Elias JA, Lee CG, Hu B, Herazo-Maya JD, Knight DA, Hogaboam CM, Herzog EL. JCI Insight. 2017 Aug 17; 2017 Aug 17. PMID: 28814671.
• Validation of the prognostic value of MMP-7 in idiopathic pulmonary fibrosis.Tzouvelekis A, Herazo-Maya JD, Slade M, Chu JH, Deiuliis G, Ryu C, Li Q, Sakamoto K, Ibarra G, Pan H, Gulati M, Antin-Ozerkis D, Herzog EL, Kaminski N. Respirology. 2017 Apr; 2016 Oct 19. PMID: 27761978.
• SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N. Am J Respir Crit Care Med. 2017 Feb 15. PMID: 27736153.
• Upper Airway Obstruction Requiring Emergent Tracheostomy Secondary to Laryngeal Sarcoidosis: A Case Report.Ryu C, Herzog EL, Pan H, Homer R, Gulati M. Am J Case Rep. 2017 Feb 13; 2017 Feb 13. PMID: 28190872.
• Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL. FASEB J. 2016 Dec; 2016 Sep 8. PMID: 27609773.
• Regulatory T Cells in Idiopathic Pulmonary Fibrosis: Too Much of a Good Thing?Moore MW, Herzog EL. Am J Pathol. 2016 Aug; 2016 Jun 23. PMID: 27344432.
• Right atrial pressure/pulmonary artery wedge pressure ratio: A more specific predictor of survival in pulmonary arterial hypertension.Fares WH, Bellumkonda L, Tonelli AR, Carson SS, Hassoun PM, Trow TK, Herzog EL, Kaminski N, Kholdani CA, Zhang L, Zhou Y, Hammel JP, Dweik RA. J Heart Lung Transplant. 2016 Jun; 2016 Jan 8. PMID: 26856665.
• RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis.Ma B, Herzog EL, Moore M, Lee CM, Na SH, Lee CG, Elias JA. Sci Rep. 2016 May 20; 2016 May 20. PMID: 27198666.
• The Airway in Idiopathic Pulmonary Fibrosis: Protecting the Lung or Promoting Disease?Ryu C, Homer RJ, Herzog EL. Am J Respir Crit Care Med. 2016 May 15. PMID: 27174477.
• Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis.Sun H, Zhu Y, Pan H, Chen X, Balestrini JL, Lam TT, Kanyo JE, Eichmann A, Gulati M, Fares WH, Bai H, Feghali-Bostwick CA, Gan Y, Peng X, Moore MW, White ES, Sava P, Gonzalez AL, Cheng Y, Niklason LE, Herzog EL. Arthritis Rheumatol. 2016 May. PMID: 26749424.
• Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype.Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA. J Biol Chem. 2016 Mar 18; 2016 Jan 13. PMID: 26763235.
• Fate of distal lung epithelium cultured in a decellularized lung extracellular matrix.Calle EA, Mendez JJ, Ghaedi M, Leiby KL, Bove PF, Herzog EL, Sundaram S, Niklason LE. Tissue Eng Part A. 2015 Jun; 2015 May 4. PMID: 25789725.
• Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis.Ma B, Herzog EL, Lee CG, Peng X, Lee CM, Chen X, Rockwell S, Koo JS, Kluger H, Herbst RS, Sznol M, Elias JA. Cancer Res. 2015 Feb 1; 2014 Dec 15. PMID: 25511377.
• Flow Cytometric Identification of Fibrocytes in the Human Circulation.Hu X, DeBiasi EM, Herzog EL. Methods Mol Biol. 2015. PMID: 26420706.
• Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?Herzog EL, Mathur A, Tager AM, Feghali-Bostwick C, Schneider F, Varga J. Arthritis Rheumatol. 2014 Aug. PMID: 24838199.
• Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis.Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL. Sci Transl Med. 2014 Jun 11. PMID: 24920662.
• CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung.Peng X, Moore MW, Peng H, Sun H, Gan Y, Homer RJ, Herzog EL. Front Pharmacol. 2014; 2014 May 16. PMID: 24904415.
• Fibroblast engraftment in the decellularized mouse lung occurs via a β1-integrin-dependent, FAK-dependent pathway that is mediated by ERK and opposed by AKT.Sun H, Calle E, Chen X, Mathur A, Zhu Y, Mendez J, Zhao L, Niklason L, Peng X, Peng H, Herzog EL. Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15; 2013 Dec 13. PMID: 24337923.
• MMP28 and macrophage polarization: orchestrating the attack of the mac.Gan Y, Herzog EL. J Leukoc Biol. 2014 Jan. PMID: 24385575.
• Regulation and Relevance of Myofibroblast Responses in Idiopathic Pulmonary Fibrosis.Moore MW, Herzog EL. Curr Pathobiol Rep. 2013 Sep. PMID: 25705577.
• Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2.He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, Elias JA. Cell Rep. 2013 Aug 29; 2013 Aug 22. PMID: 23972995.
• Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL. Am J Respir Crit Care Med. 2013 Jan 15; 2012 Dec 6. PMID: 23220917.
• Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling.Lee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA. J Immunol. 2012 Sep 1; 2012 Jul 23. PMID: 22826322.
• Flow cytometric identification of fibrocytes in scleroderma lung disease.Russell TM, Herzog EL, Bucala R. Methods Mol Biol. 2012. PMID: 22933077.
• Fibrocytes: emerging effector cells in chronic inflammation.Reilkoff RA, Bucala R, Herzog EL. Nat Rev Immunol. 2011 Jun; 2011 May 20. PMID: 21597472.
• Local apoptosis promotes collagen production by monocyte-derived cells in transforming growth factor β1-induced lung fibrosis.Peng X, Mathai SK, Murray LA, Russell T, Reilkoff R, Chen Q, Gulati M, Elias JA, Bucala R, Gan Y, Herzog EL. Fibrogenesis Tissue Repair. 2011 May 17; 2011 May 17. PMID: 21586112.
• Recent advances in pulmonary fibrosis: implications for scleroderma.Homer RJ, Herzog EL. Curr Opin Rheumatol. 2010 Nov. PMID: 20693906.
• Fibrocytes in health and disease.Herzog EL, Bucala R. Exp Hematol. 2010 Jul; 2010 Mar 18. PMID: 20303382.
• Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL. Lab Invest. 2010 Jun; 2010 Apr 19. PMID: 20404807.
• Of lungs, lipids, and lollipops.Mathai SK, Rubinowitz AN, Homer RJ, Detterbeck F, Herzog EL. Chest. 2009 Nov. PMID: 19892683.
• Knowns and unknowns of the alveolus.Herzog EL, Brody AR, Colby TV, Mason R, Williams MC. Proc Am Thorac Soc. 2008 Sep 15. PMID: 18757317.
• Lung-specific nuclear reprogramming is accompanied by heterokaryon formation and Y chromosome loss following bone marrow transplantation and secondary inflammation.Herzog EL, Van Arnam J, Hu B, Zhang J, Chen Q, Haberman AM, Krause DS. FASEB J. 2007 Aug; 2007 Apr 20. PMID: 17449722.
• Engraftment of marrow-derived epithelial cells: the role of fusion.Herzog EL, Krause DS. Proc Am Thorac Soc. 2006 Nov. PMID: 17065375.
• Threshold of lung injury required for the appearance of marrow-derived lung epithelia.Herzog EL, Van Arnam J, Hu B, Krause DS. Stem Cells. 2006 Aug. PMID: 16868209.
• Bone marrow-derived cells contribute to epithelial engraftment during wound healing.Borue X, Lee S, Grove J, Herzog EL, Harris R, Diflo T, Glusac E, Hyman K, Theise ND, Krause DS. Am J Pathol. 2004 Nov. PMID: 15509544.
• Lack of a fusion requirement for development of bone marrow-derived epithelia.Harris RG, Herzog EL, Bruscia EM, Grove JE, Van Arnam JS, Krause DS. Science. 2004 Jul 2. PMID: 15232107.
• Plasticity of marrow-derived stem cells.Herzog EL, Chai L, Krause DS. Blood. 2003 Nov 15; 2003 Jul 31. PMID: 12893756.