Activation of RhoA, Smad2, c‐Src, PKC‐βII/δ and JNK in atopic dermatitis
Lu J, Yin R, Fu Z, Lee V, Nelson J, Tan W. Activation of RhoA, Smad2, c‐Src, PKC‐βII/δ and JNK in atopic dermatitis. Australasian Journal Of Dermatology 2018, 59: e258-e261. PMID: 29498756, PMCID: PMC6978706, DOI: 10.1111/ajd.12801.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedDermatitis, AtopicDermisEpidermisFemaleHumansJNK Mitogen-Activated Protein KinasesMaleMiddle AgedPhosphorylationProtein Kinase C betaReceptor, Transforming Growth Factor-beta Type IRhoA GTP-Binding ProteinSeverity of Illness IndexSmad2 ProteinSrc-Family KinasesUp-RegulationYoung AdultConceptsExpression of TGFβR1Atopic dermatitisAtopic dermatitis severityInfiltrated inflammatory cellsMultifactorial skin diseaseActivation of Smad2C-SrcDermatitis severityInflammatory progressionInflammatory cellsSkin diseasesActivation of RhoAPhosphorylation levelsDermatitisTGFβR1JNKSmad2ActivationInflammationChronicPathogenesisExpressionRhoADiseaseProgression