Immune cells are an ally, not enemy, in battle against Alzheimer’s
In Alzheimer’s disease (AD), β-amyloid plaques are tightly enveloped by microglia but the significance of this phenomenon is unknown. Here the authors used confocal and in vivo two-photon imaging in AD mouse models and revealed that microglia constitute a physical barrier that prevents the formation of neurotoxic hotspots of protofibrillar β-amyloid and shields adjacent neurons and synapses from the toxic effect of amyloid plaques
Environmental Injustice and Cumulative Environmental Burdens in Neighborhoods Near Oil and Gas Development: Los Angeles County, California, and Beyond
Residential proximity to oil and gas wells has been increasingly recognized to threaten the health and environmental quality of nearby communities.Source: American Journal of Public Health
Chemical compounds in extra virgin olive oil could aid in the treatment and prevention of Alzheimer’s disease
A new study led by researchers with the Yale School of Public Health’s Department of Environmental Health Sciences and Imperial College London used network machine learning algorithms to identify chemical compounds in extra virgin olive oil (EVOO) that could aid in the prevention and treatment of Alzheimer’s disease.
Neuropsychiatric behavioral symptoms are associated with the ending of marriages
Older adults with more severe behavioral symptoms, including agitation, aggression, and disinhibition, are more likely to become divorced than those with less severe symptoms. However, increasing stages of dementia are associated with a low likelihood of divorce, according to a new study published in PLOS ONE by Joan Monin of the Yale School of Public Health and colleagues.Source: EurekAlert!
Study: Low-Risk Long-Term Cancer Survivors Much More Likely to Die of Noncancer Causes
A new study led by Yale University researchers examined the cancer- and noncancer-related mortality rates of long-term adult cancer survivors to better understand and quantify their associated health risks. The findings could help reduce large-scale care inefficiencies and improve the quality of care for long-term cancer survivors, who have unique cancer and noncancer health needs.
Platelet response to influenza vaccination reflects effects of aging
A paper whose authors include several Yale School of Medicine professors, researchers and scientists recently made the cover of Aging Cell. The cover design is by Hannah Wang, Academic Support Associate, Department of Pathology.Source: Aging Cell
Study Examines Dementia Caregiver Experiences and Preparedness
As the global population ages, people providing care for more than one family member or close other across adulthood is becoming increasingly common. Yet little is known about the ways prior caregiving experiences shape an individual’s future preparedness when it comes to caring for additional people living with dementia.