Selected Publications

• Bone marrow sinusoidal endothelial cells are a site of Fgf23 upregulation in a mouse model of iron deficiency anemia.Li X, Lozovatsky L, Tommasini SM, Fretz J, Finberg KE. Blood Adv. 2023 Sep 12. PMID: 37417950.
• Hepatocellular Adenoma: Report of 2 Cases That Highlight the Relevance of Phenotype-Genotype Correlation in the Pediatric Population.Jiao J, Finberg KE, Jain D, Morotti R. Pediatr Dev Pathol. 2023 Jul-Aug; 2023 Jun 19. PMID: 37334553.
• Endometrial Carcinoma as the Presenting Malignancy in a Teenager With a Pathogenic TP53 Germline Mutation: A Case Report and Literature Review.Irshaid L, Clark M, Fadare O, Finberg KE, Parkash V. Int J Gynecol Pathol. 2022 May 1; 2021 May 12. PMID: 33990091.
• Blocking (iron) traffic in the gut.Finberg KE. Blood. 2022 Apr 21. PMID: 35446376.
• Yale Precision Medicine Tumor Board: reawakening the guardian of the genome.Grant MJ, Finberg KE, Walther Z, Stein SM, Lacy J, Eder JP, Goldberg SB. Lancet Oncol. 2022 Mar. PMID: 35240081.
• Pathogenic BRCA2 germline variants in combined hepatocellular-cholangiocarcinoma.Li H, Zhang X, Finberg KE, Walther Z, Jain D, Gibson J. Pathol Int. 2022 Feb; 2021 Nov 22. PMID: 34808016.
• Yale Cancer Center Precision Medicine Tumor Board: molecular findings alter a diagnosis and treatment plan.Gibson JA, Finberg KE, Nalbantoglu I, Cecchini M, Ganzak A, Walther Z, Sklar JL, Eder JP, Goldberg SB. Lancet Oncol. 2021 Mar. PMID: 33662283.
• Functional characterization of a novel SLC40A1 Arg88Ile mutation in a kindred with familial iron overload treated by phlebotomy.Womack J, Sukumaran A, Li X, Lozovatsky L, Gallagher PG, Seid JE, Finberg KE. Blood Cells Mol Dis. 2021 Mar; 2020 Dec 24. PMID: 33385755.
• Ironing out an approach to alleviate the hypoferremia of acute inflammation.Finberg KE. Haematologica. 2021 Feb 1; 2021 Feb 1. PMID: 33522782.
• NCOA4 is regulated by HIF and mediates mobilization of murine hepatic iron stores after blood loss.Li X, Lozovatsky L, Sukumaran A, Gonzalez L, Jain A, Liu D, Ayala-Lopez N, Finberg KE. Blood. 2020 Dec 3. PMID: 32659785.
• EBV-Positive Primary Large B-Cell Lymphoma: The Role of Immunohistochemistry and XPO1 in the Diagnosis of Mediastinal Lymphomas.Maracaja DLV, Puthenpura V, Pels SG, O'Malley DP, Sklar JL, Finberg KE, Xu ML. Appl Immunohistochem Mol Morphol. 2020 Nov/Dec. PMID: 31789821.
• IL-1β Drives Production of FGF-23 at the Onset of Chronic Kidney Disease in Mice.McKnight Q, Jenkins S, Li X, Nelson T, Marlier A, Cantley LG, Finberg KE, Fretz JA. J Bone Miner Res. 2020 Jul; 2020 May 27. PMID: 32154933.
• Yale Cancer Center Precision Medicine Tumor Board: new technology, new drugs, and the value of repeat testing.Hafez N, Walther Z, Eder JP, Sklar JL, Gettinger SN, Finberg KE, Goldberg SB. Lancet Oncol. 2020 Mar; 2020 Mar 2. PMID: 32950226.
• Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.Xavier-Ferrucio J, Scanlon V, Li X, Zhang PX, Lozovatsky L, Ayala-Lopez N, Tebaldi T, Halene S, Cao C, Fleming MD, Finberg KE, Krause DS. Blood. 2019 Oct 31. PMID: 31439541.
• Going solo in iron transport.Finberg KE. Blood. 2019 Oct 24. PMID: 31698431.
• Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia.Stagg DB, Whittlesey RL, Li X, Lozovatsky L, Gardenghi S, Rivella S, Finberg KE. Haematologica. 2019 Oct; 2019 Feb 28. PMID: 30819909.
• Yale Cancer Center Precision Medicine Tumor Board: one tumour, multiple targets.Stewart T, Finberg K, Walther Z, Sklar JL, Hafez N, Eder JP, Anderson K, Wilson F, Goldberg SB. Lancet Oncol. 2018 Dec; 2018 Nov 28. PMID: 32956641.
• Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency.Heeney MM, Guo D, De Falco L, Campagna DR, Olbina G, Kao PP, Schmitz-Abe K, Rahimov F, Gutschow P, Westerman K, Ostland V, Jackson T, Klaassen RJ, Markianos K, Finberg KE, Iolascon A, Westerman M, London WB, Fleming MD. Blood. 2018 Jul 26; 2018 Jun 12. PMID: 29895660.
• Ironing out the role of Toll-like receptors.Finberg KE. Blood. 2015 Apr 2. PMID: 25838278.
• Iron-refractory iron deficiency anemia (IRIDA).Heeney MM, Finberg KE. Hematol Oncol Clin North Am. 2014 Aug; 2014 May 28. PMID: 25064705.
• Regulation of systemic iron homeostasis.Finberg KE. Curr Opin Hematol. 2013 May. PMID: 23426198.
• Striking the target in iron overload disorders.Finberg KE. J Clin Invest. 2013 Apr; 2013 Mar 25. PMID: 23524962.
• Iron refractory iron deficiency anemia: presentation with hyperferritinemia and response to oral iron therapy.Khuong-Quang DA, Schwartzentruber J, Westerman M, Lepage P, Finberg KE, Majewski J, Jabado N. Pediatrics. 2013 Feb; 2013 Jan 14. PMID: 23319530.
• Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.Finberg KE, Whittlesey RL, Andrews NC. Blood. 2011 Apr 28; 2011 Feb 25. PMID: 21355094.
• Unraveling mechanisms regulating systemic iron homeostasis.Finberg KE. Hematology Am Soc Hematol Educ Program. 2011. PMID: 22160085.
• Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.Finberg KE, Whittlesey RL, Fleming MD, Andrews NC. Blood. 2010 May 6; 2010 Mar 3. PMID: 20200349.
• Iron-refractory iron deficiency anemia.Finberg KE. Semin Hematol. 2009 Oct. PMID: 19786206.
• Iron homeostasis: casting new roles.Finberg KE. Blood. 2008 Sep 15. PMID: 18779402.
• Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA).Finberg KE, Heeney MM, Campagna DR, Aydinok Y, Pearson HA, Hartman KR, Mayo MM, Samuel SM, Strouse JJ, Markianos K, Andrews NC, Fleming MD. Nat Genet. 2008 May; 2008 Apr 13. PMID: 18408718.