2022
The CD8α–PILRα interaction maintains CD8+ T cell quiescence
Zheng L, Han X, Yao S, Zhu Y, Klement J, Wu S, Ji L, Zhu G, Cheng X, Tobiasova Z, Yu W, Huang B, Vesely MD, Wang J, Zhang J, Quinlan E, Chen L. The CD8α–PILRα interaction maintains CD8+ T cell quiescence. Science 2022, 376: 996-1001. PMID: 35617401, DOI: 10.1126/science.aaz8658.Peer-Reviewed Original ResearchConceptsT cell quiescenceT cellsT cell pool sizeMaintenance of CD8Peripheral lymphoid organsCell quiescenceMemory CD8Antigen exposureLymphoid organsActivation phenotypeCD8Specific antigenCD8αInducible deletionCell pool sizeDiverse antigensAntigenMolecular mechanismsBroad repertoireExposureCellsQuiescent stateTumorsMicePILRα
2012
[Experimental study of inhibition of tumor cell proliferation by a novel gene SPATA12].
Liu Z, Lin Y, Liu X, Yu W, Zhang Y, Li D. [Experimental study of inhibition of tumor cell proliferation by a novel gene SPATA12]. Journal Of Central South University Medical Sciences 2012, 37: 222-7. PMID: 22561491, DOI: 10.3969/j.issn.1672-7347.2012.03.002.Peer-Reviewed Original ResearchConceptsTumor cell proliferationTesticular tumorsCell proliferationColony formationReverse transcription-polymerase chainSitu hybridization analysisTranscription-polymerase chainNormal adult testisDevelopment of tumorsDiphenyl tetrazolium bromideCell cycle genesTissue microarrayCyclin D1MRNA expressionTumor cellsInhibitory roleCyclin A1 geneCyclin E1RT-PCRTumorsDimethylthiazol-2MTT assayTetrazolium bromideCyclin B1Expression levels