2022
Improving quality of life post-tumor craniotomy using personalized, parcel-guided TMS: safety and proof of concept
Tang S, Holle J, Lesslar O, Teo C, Sughrue M, Yeung J. Improving quality of life post-tumor craniotomy using personalized, parcel-guided TMS: safety and proof of concept. Journal Of Neuro-Oncology 2022, 160: 413-422. PMID: 36308593, DOI: 10.1007/s11060-022-04160-y.Peer-Reviewed Original ResearchConceptsRepetitive transcranial magnetic stimulationNeuro-cognitive dysfunctionRTMS treatmentBeck Depression InventoryFunctional deficitsNeurological disordersDepression InventoryPost-operative depressionTranscranial magnetic stimulationNeuro-cognitive deficitsNeuro-cognitive functionsMultiple cortical targetsFunctional connectivity approachNon-invasive toolEuroQol qualityNeuropsychiatric questionnaireResultsNine patientsAdverse eventsRetrospective reviewSurgical removalTMS treatmentCortical targetsShort-term memory difficultiesBrain tumorsDepressive symptoms
2020
Unexpected hubness: a proof-of-concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery
Yeung JT, Taylor HM, Young IM, Nicholas PJ, Doyen S, Sughrue ME. Unexpected hubness: a proof-of-concept study of the human connectome using pagerank centrality and implications for intracerebral neurosurgery. Journal Of Neuro-Oncology 2020, 151: 249-256. PMID: 33170473, DOI: 10.1007/s11060-020-03659-6.Peer-Reviewed Original ResearchConceptsIntracerebral surgeryHealthy cohortSubset of individualsSupratentorial neurosurgeryCohortBrain regionsHuman connectomeParcellation schemesParcellationNeurosurgeryConcept studyPersonalized levelPotential effectsConnectomeSurgeryQuartile rankMethodsWePrevalenceResultsInIndividualsBrainNeurosurgeons
2016
Macrovascular Lesions Underlying Spontaneous Intracerebral Hemorrhage
Yeung J, Cord BJ, O'Rourke TK, Maina RM, Sommaruga S, Matouk CC. Macrovascular Lesions Underlying Spontaneous Intracerebral Hemorrhage. Seminars In Neurology 2016, 36: 244-253. PMID: 27214699, DOI: 10.1055/s-0036-1581994.Peer-Reviewed Original ResearchConceptsSpontaneous intracerebral hemorrhageIntracerebral hemorrhageMacrovascular lesionsHigh case fatality rateCranial dural arteriovenous fistulasBrain arteriovenous malformationsCase fatality rateDural arteriovenous fistulaEtiology of hemorrhageCerebral cavernous malformationsRehemorrhage rateArteriovenous fistulaMorbid diseaseArteriovenous malformationsCavernous malformationsFatality rateClinical decisionHemorrhageLesionsMalformationsFistulaPrognosisAneurysmsEtiologyDiseaseHigh-resolution Vessel Wall Magnetic Resonance Imaging in Intracranial Aneurysms and Brain Arteriovenous Malformations
Matouk CC, Cord BJ, Yeung J, Malhotra A, Johnson MH, Minja FJ. High-resolution Vessel Wall Magnetic Resonance Imaging in Intracranial Aneurysms and Brain Arteriovenous Malformations. Topics In Magnetic Resonance Imaging 2016, 25: 49-55. PMID: 27049241, DOI: 10.1097/rmr.0000000000000084.Peer-Reviewed Original ResearchConceptsHigh-resolution vessel wall magnetic resonance imagingVessel wall magnetic resonance imagingMagnetic resonance imagingArteriovenous malformationsResonance imagingIntracranial aneurysmsSteno-occlusive diseaseBrain arteriovenous malformationsCerebrovascular diseaseClinical evaluationAcademic centersClinical practiceVW-MRIConventional imagingAneurysmsMalformationsDisease
2012
Increased expression of tumor-associated antigens in pediatric and adult ependymomas: implication for vaccine therapy
Yeung JT, Hamilton RL, Okada H, Jakacki RI, Pollack IF. Increased expression of tumor-associated antigens in pediatric and adult ependymomas: implication for vaccine therapy. Journal Of Neuro-Oncology 2012, 111: 103-111. PMID: 23179498, PMCID: PMC3546121, DOI: 10.1007/s11060-012-0998-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overAntigens, NeoplasmBrainBrain NeoplasmsCancer VaccinesChildChild, PreschoolEpendymomaFemaleGene Expression Regulation, NeoplasticHistocompatibility Antigens Class IHumansInfantInhibitor of Apoptosis ProteinsInterleukin-13 Receptor alpha1 SubunitMaleMiddle AgedReceptor, EphA2SurvivinWT1 ProteinsConceptsTumor-associated antigensMore tumor-associated antigensIL-13Rα2Positive stainingAdult ependymomasMultiple peptides vaccineNormal brain tissueGlioma vaccinesImmunotherapy approachesVaccine therapyPediatric casesAdult casesTumor recurrenceClinical trialsPeptide vaccinePediatric ependymomaNormal brainEpendymomaBrain tissuePediatric gliomasTumor 1SurvivinStainingEphA2Vaccine