Publications

Prodrug nanotherapy demonstrates in vivo anticryptosporidial efficacy in a mouse model of chronic Cryptosporidium infection.Ranjan AP, Czyzyk DJ, Martinez-Traverso G, Sadiqova A, Valhondo M, Schaefer DA, Spasov KA, Jorgensen WL, Vishwanatha JK, Riggs MW, Castellanos-Gonzalez A, Anderson KS. RSC Pharm. 2024 Dec 10; 2024 Sep 19. PMID: 39372445.
Applications of a Rayleigh-Taylor model to direct-drive laser fusion.Thomas CA, Rosenberg MJ, Theobald W, Knauer JP, Stoeckl C, Regan SP, Collins TJB, Goncharov VN, Betti R, Froula D, Deeney C, Anderson KS, Bauer KA, Bonino MJ, Cao D, Craxton RS, Edgell DH, Epstein R, Fess S, Forrest CJ, Glebov VY, Gopalaswamy V, Harding DR, Igumenshchev IV, Ivancic ST, Jacobs-Perkins DW, Janezic RT, Joshi T, Koch M, Kwiatkowski J, Lees A, Marshall FJ, Michalko M, Morse SFB, Patel D, Peebles JL, Radha PB, Rinderknecht HG, Sampat S, Sangster TC, Shah RC, Shmayda WT, Turnbull D, Williams CA, Campbell EM, Christopherson AR, Tabak M, Alexander NB, Farrell MP, Shuldberg C. Phys Rev E. 2024 Oct. PMID: 39562888.
RAD52 resolves transcription-replication conflicts to mitigate R-loop induced genome instability.Jalan M, Sharma A, Pei X, Weinhold N, Buechelmaier ES, Zhu Y, Ahmed-Seghir S, Ratnakumar A, Di Bona M, McDermott N, Gomez-Aguilar J, Anderson KS, Ng CKY, Selenica P, Bakhoum SF, Reis-Filho JS, Riaz N, Powell SN. Nat Commun. 2024 Sep 5; 2024 Sep 5. PMID: 39237529.
Persistent Hot-Spot Mix in Cryogenic Direct-Drive Fusion Experiments.Shah RC, Cao D, Igumenshchev IV, Goncharov VN, Anderson KS, Bauer KA, Betti R, Bonino MJ, Campbell EM, Colaïtis A, Collins TJB, Churnetski K, Forrest CJ, Froula DH, Glebov VY, Gopalaswamy V, Harding DR, Hu SX, Janezic RT, Kwiatkowski J, Lees A, Morse SFB, Miller S, Patel D, Regan SP, Sampat S, Thomas CA, Turnbull D. Phys Rev Lett. 2024 Aug 30. PMID: 39270173.
Proof-of-concept studies with a computationally designed M(pro) inhibitor as a synergistic combination regimen alternative to Paxlovid.Papini C, Ullah I, Ranjan AP, Zhang S, Wu Q, Spasov KA, Zhang C, Mothes W, Crawford JM, Lindenbach BD, Uchil PD, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2024 Apr 23; 2024 Apr 15. PMID: 38621119.
The electrostatic landscape of MHC-peptide binding revealed using inception networks.Wilson E, Cava JK, Chowell D, Raja R, Mangalaparthi KK, Pandey A, Curtis M, Anderson KS, Singharoy A. Cell Syst. 2024 Apr 17; 2024 Mar 29. PMID: 38554709.
Autoantibodies, antigen-autoantibody complexes and antigens complement CA125 for early detection of ovarian cancer.Young Han C, Bedia JS, Yang WL, Hawley SJ, Bergan L, Hopper M, Celestino J, Guo J, Gornet TG, Soosaipillai A, Yang H, Doskocil SD, Lokshin AE, Handy BC, Diamandis EP, Moore RG, Lu KH, Lu Z, Anderson KS, Drescher CW, Skates SJ, Bast RC Jr. Br J Cancer. 2024 Mar; 2024 Jan 9. PMID: 38195887.
Quantitative assessment of multiple pathogen exposure and immune dynamics at scale.Song L, Rauf F, Hou C-W, Qiu J, Murugan V, Chung Y, Lai H, Adam D, Magee DM, Trivino Soto G, Peterson M, Anderson KS, Rice SG, Readhead B, Park JG, LaBaer J. Microbiol Spectr. 2024 Jan 11; 2023 Dec 8. PMID: 38063388.
Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer.Seyedi S, Teo R, Foster L, Saha D, Mina L, Northfelt D, Anderson KS, Shibata D, Gatenby R, Cisneros LH, Troan B, Anderson ARA, Maley CC. Cancers (Basel). 2024 Jan 6; 2024 Jan 6. PMID: 38254748.
Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase.Prucha GR, Henry S, Hollander K, Carter ZJ, Spasov KA, Jorgensen WL, Anderson KS. Eur J Med Chem. 2023 Dec 15; 2023 Oct 20. PMID: 37883896.
Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise.Hollander K, Chan AH, Frey KM, Hunker O, Ippolito JA, Spasov KA, Yeh YJ, Jorgensen WL, Ho YC, Anderson KS. Protein Sci. 2023 Dec. PMID: 37861472.
A High-Throughput, High-Containment Human Primary Epithelial Airway Organ-on-Chip Platform for SARS-CoV-2 Therapeutic Screening.Fisher CR, Mba Medie F, Luu RJ, Gaibler RB, Mulhern TJ, Miller CR, Zhang CJ, Rubio LD, Marr EE, Vijayakumar V, Gabriel EP, Lopez Quezada L, Zhang CH, Anderson KS, Jorgensen WL, Alladina JW, Medoff BD, Borenstein JT, Gard AL. Cells. 2023 Nov 16; 2023 Nov 16. PMID: 37998374.
Examining ways to score the Epidemic-Pandemic Impacts Inventory in parents of young children.Ratcliff CG, Torres D, Anderson KS, Langley HA. Psychol Assess. 2023 Nov. PMID: 37902666.
Testing Adaptive Therapy Protocols using Gemcitabine and Capecitabine on a Mouse Model of Endocrine-Resistant Breast Cancer.Seyedi S, Teo R, Foster L, Saha D, Mina L, Northfelt D, Anderson KS, Shibata D, Gatenby R, Cisneros L, Troan B, Anderson ARA, Maley CC. bioRxiv. 2023 Sep 22; 2023 Sep 22. PMID: 37781632.
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.Schrank TP, Kothari A, Weir WH, Stepp WH, Rehmani H, Liu X, Wang X, Sewell A, Li X, Tasoulas J, Kim S, Yarbrough G, Xie Y, Flamand Y, Marur S, Hayward MC, Wu D, Burtness B, Anderson KS, Baldwin AS, Yarbrough WG, Issaeva N. Proc Natl Acad Sci U S A. 2023 Aug 8; 2023 Jul 31. PMID: 37523561.
Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy.Wang Z, Muthusamy V, Petrylak DP, Anderson KS. NPJ Precis Oncol. 2023 Jul 21; 2023 Jul 21. PMID: 37479885.
Design, synthesis, and biological testing of biphenylmethyloxazole inhibitors targeting HIV-1 reverse transcriptase.Carter ZJ, Hollander K, Spasov KA, Anderson KS, Jorgensen WL. Bioorg Med Chem Lett. 2023 Mar 15; 2023 Mar 3. PMID: 36871704.
Immunogenicity of CRISPR therapeutics-Critical considerations for clinical translation.Ewaisha R, Anderson KS. Front Bioeng Biotechnol. 2023; 2023 Feb 16. PMID: 36873375.
PDJ amplicon in triple negative breast cancer.Roesler AS, Malasi S, Koslosky L, Hartmayer P, Naab TJ, Carter JM, Zahrieh D, Hillman D, Leon-Ferre RA, Couch FJ, Goetz MP, Anderson KS, Pockaj BA, Barrett MT. Sci Rep. 2023 Jan 12; 2023 Jan 12. PMID: 36635351.
Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.Gannam ZTK, Jamali H, Kweon OS, Herrington J, Shillingford SR, Papini C, Gentzel E, Lolis E, Bennett AM, Ellman JA, Anderson KS. Eur J Med Chem. 2022 Dec 5; 2022 Sep 2. PMID: 36116232.
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies.Lidsky ME, Wang Z, Lu M, Liu A, Hsu SD, McCall SJ, Sheng Z, Granek JA, Owzar K, Anderson KS, Wood KC. NPJ Precis Oncol. 2022 Oct 23; 2022 Oct 23. PMID: 36274097.
Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.Papini C, Wang Z, Kudalkar SN, Schrank TP, Tang S, Sasaki T, Wu C, Tejada B, Ziegler SJ, Xiong Y, Issaeva N, Yarbrough WG, Anderson KS. iScience. 2022 Oct 21; 2022 Oct 7. PMID: 36248736.
Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.Papini C, Wang Z, Kudalkar SN, Schrank TP, Tang S, Sasaki T, Wu C, Tejada B, Ziegler SJ, Xiong Y, Issaeva N, Yarbrough WG, Anderson KS. iScience. 2022 Oct 21; 2022 Sep 5. PMID: 36164654.
Development of an x-ray radiography platform to study laser-direct-drive energy coupling at the National Ignition Facility.Ceurvorst L, Theobald W, Rosenberg MJ, Radha PB, Stoeckl C, Betti R, Anderson KS, Marozas JA, Goncharov VN, Campbell EM, Shuldberg CM, Luo RW, Sweet W, Aghaian L, Carlson L, Bachmann B, Döppner T, Hohenberger M, Glize K, Scott RHH, Colaïtis A, Regan SP. Rev Sci Instrum. 2022 Oct 1. PMID: 36319381.
Therapeutic Targeting of FGFR Signaling in Head and Neck Cancer.Wang Z, Anderson KS. Cancer J. 2022 Sep-Oct 01. PMID: 36165723.
APOBEC mutagenesis and selection for NFE2L2 contribute to the origin of lung squamous-cell carcinoma.Cannataro VL, Kudalkar S, Dasari K, Gaffney SG, Lazowski HM, Jackson LK, Yildiz I, Das RK, Gould Rothberg BE, Anderson KS, Townsend JP. Lung Cancer. 2022 Sep; 2022 Jul 9. PMID: 35872531.
An ultra-brief screening scale for pediatric obsessive-compulsive disorder: The OCI-CV-5.Abramovitch A, Abramowitz JS, McKay D, Cham H, Anderson KS, Farrell LJ, Geller DA, Hanna GL, Mathieu S, McGuire JF, Rosenberg DR, Stewart SE, Storch EA, Wilhelm S. J Affect Disord. 2022 Sep 1; 2022 Jun 11. PMID: 35697331.
Using the Biopsychosocial Approach to Identify Factors Associated with Major Depressive Disorder for Individuals with Hypothyroidism.Anderson KS, Howard KJ, Haskard-Zolnierek KB, Pruin J, Deason RG. Issues Ment Health Nurs. 2022 Aug; 2022 Mar 31. PMID: 35358004.
Is 2045 the best we can do? Mitigating the HPV-related oropharyngeal cancer epidemic.Schuman A, Anderson KS, Day AT, Ferrell J, Sturgis EM, Dahlstrom KR. Expert Rev Anticancer Ther. 2022 Jul; 2022 Jun 17. PMID: 35679626.
The feasibility of using an autologous GM-CSF-secreting breast cancer vaccine to induce immunity in patients with stage II-III and metastatic breast cancers.Anderson KS, Erick TK, Chen M, Daley H, Campbell M, Colson Y, Mihm M, Zakka LR, Hopper M, Barry W, Winer EP, Dranoff G, Overmoyer B. Breast Cancer Res Treat. 2022 Jul; 2022 Apr 28. PMID: 35482127.
The OCI-CV-R: A Revision of the Obsessive-Compulsive Inventory - Child Version.Abramovitch A, Abramowitz JS, McKay D, Cham H, Anderson KS, Farrell L, Geller DA, Hanna GL, Mathieu S, McGuire JF, Rosenberg DR, Stewart SE, Storch EA, Wilhelm S. J Anxiety Disord. 2022 Mar; 2022 Jan 15. PMID: 35091252.
Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase.Frey KM, Bertoletti N, Chan AH, Ippolito JA, Bollini M, Spasov KA, Jorgensen WL, Anderson KS. Front Mol Biosci. 2022; 2022 Feb 14. PMID: 35237658.
Long-acting and extended-release implant and nanoformulations with a synergistic antiretroviral two-drug combination controls HIV-1 infection in a humanized mouse model.Beloor J, Kudalkar SN, Buzzelli G, Yang F, Mandl HK, Rajashekar JK, Spasov KA, Jorgensen WL, Saltzman WM, Anderson KS, Kumar P. Bioeng Transl Med. 2022 Jan; 2021 Jun 26. PMID: 35079625.
Beyond Sequencing: Prioritizing and Delivering Neoantigens for Cancer Vaccines.Roesler AS, Anderson KS. Methods Mol Biol. 2022. PMID: 34914074.
Pitch and Rhythm Perception and Verbal Short-Term Memory in Acute Traumatic Brain Injury.Anderson KS, Gosselin N, Sadikot AF, Laguë-Beauvais M, Kang ESH, Fogarty AE, Marcoux J, Dagher J, de Guise E. Brain Sci. 2021 Sep 3; 2021 Sep 3. PMID: 34573194.
Experimentally Inferred Fusion Yield Dependencies of OMEGA Inertial Confinement Fusion Implosions.Lees A, Betti R, Knauer JP, Gopalaswamy V, Patel D, Woo KM, Anderson KS, Campbell EM, Cao D, Carroll-Nellenback J, Epstein R, Forrest C, Goncharov VN, Harding DR, Hu SX, Igumenshchev IV, Janezic RT, Mannion OM, Radha PB, Regan SP, Shvydky A, Shah RC, Shmayda WT, Stoeckl C, Theobald W, Thomas C. Phys Rev Lett. 2021 Sep 3. PMID: 34533333.
Screening for HPV-related oropharyngeal, anal, and penile cancers in middle-aged men: Initial report from the HOUSTON clinical trial.Dahlstrom KR, Anderson KS, Guo M, Kwon MC, Messick CA, Pettaway CA, Asomaning N, Hopper M, Price A, Xu L, Day AT, Gillenwater AM, Sturgis EM. Oral Oncol. 2021 Sep; 2021 Jun 26. PMID: 34182223.
Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.Zhang CH, Spasov KA, Reilly RA, Hollander K, Stone EA, Ippolito JA, Liosi ME, Deshmukh MG, Tirado-Rives J, Zhang S, Liang Z, Miller SJ, Isaacs F, Lindenbach BD, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2021 Aug 12; 2021 Jul 14. PMID: 34408808.
Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease.Deshmukh MG, Ippolito JA, Zhang CH, Stone EA, Reilly RA, Miller SJ, Jorgensen WL, Anderson KS. Structure. 2021 Aug 5; 2021 Jun 22. PMID: 34161756.
Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell.Hussain SS, Majumdar R, Moore GM, Narang H, Buechelmaier ES, Bazil MJ, Ravindran PT, Leeman JE, Li Y, Jalan M, Anderson KS, Farina A, Soni R, Mohibullah N, Hamzic E, Rong-Mullins X, Sifuentes C, Damerla RR, Viale A, Powell SN, Higginson DS. Nucleic Acids Res. 2021 Jul 21. PMID: 33877327.
Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation.Wu K, Wu H, Lyu W, Kim Y, Furdui CM, Anderson KS, Koleske AJ. J Biol Chem. 2021 Jul; 2021 Jun 16. PMID: 34144039.
Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity.Phung TN, Webster TH, Lenkiewicz E, Malasi S, Andreozzi M, McCullough AE, Anderson KS, Pockaj BA, Wilson MA, Barrett MT. Sci Rep. 2021 May 19; 2021 May 19. PMID: 34011996.
Public health impact of delaying second dose of BNT162b2 or mRNA-1273 covid-19 vaccine: simulation agent based modeling study.Romero-Brufau S, Chopra A, Ryu AJ, Gel E, Raskar R, Kremers W, Anderson KS, Subramanian J, Krishnamurthy B, Singh A, Pasupathy K, Dong Y, O'Horo JC, Wilson WR, Mitchell O, Kingsley TC. BMJ. 2021 May 12; 2021 May 12. PMID: 33980718.
Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.Zhang CH, Stone EA, Deshmukh M, Ippolito JA, Ghahremanpour MM, Tirado-Rives J, Spasov KA, Zhang S, Takeo Y, Kudalkar SN, Liang Z, Isaacs F, Lindenbach B, Miller SJ, Anderson KS, Jorgensen WL. ACS Cent Sci. 2021 Mar 24; 2021 Feb 22. PMID: 33786375.
Total predicted MHC-I epitope load is inversely associated with population mortality from SARS-CoV-2.Wilson EA, Hirneise G, Singharoy A, Anderson KS. Cell Rep Med. 2021 Mar 16; 2021 Feb 25. PMID: 33649748.
Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead.Ippolito JA, Niu H, Bertoletti N, Carter ZJ, Jin S, Spasov KA, Cisneros JA, Valhondo M, Cutrona KJ, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2021 Feb 11; 2021 Jan 6. PMID: 33603971.
Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.Hajek M, Biktasova A, Sewell A, Gary C, Cantalupo P, Anderson KS, Yarbrough WG, Issaeva N. Cancers (Basel). 2020 Dec 23; 2020 Dec 23. PMID: 33374558.
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2.Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, Cabeza de Vaca I, Liosi ME, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2020 Dec 10; 2020 Oct 25. PMID: 33324471.
Biomarkers and Strategies for Early Detection of Ovarian Cancer.Bast RC Jr, Lu Z, Han CY, Lu KH, Anderson KS, Drescher CW, Skates SJ. Cancer Epidemiol Biomarkers Prev. 2020 Dec; 2020 Oct 13. PMID: 33051337.
Autoantibodies in Early Detection of Breast Cancer.Rauf F, Anderson KS, LaBaer J. Cancer Epidemiol Biomarkers Prev. 2020 Dec; 2020 Sep 29. PMID: 32994341.
Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.Bertoletti N, Chan AH, Schinazi RF, Anderson KS. Molecules. 2020 Oct 21; 2020 Oct 21. PMID: 33096918.
Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site.Duong VN, Ippolito JA, Chan AH, Lee WG, Spasov KA, Jorgensen WL, Anderson KS. Protein Sci. 2020 Sep; 2020 Aug 5. PMID: 32643196.
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2.Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, de Vaca IC, Liosi ME, Anderson KS, Jorgensen WL. bioRxiv. 2020 Aug 28; 2020 Aug 28. PMID: 32869018.
An allosteric site on MKP5 reveals a strategy for small-molecule inhibition.Gannam ZTK, Min K, Shillingford SR, Zhang L, Herrington J, Abriola L, Gareiss PC, Pantouris G, Tzouvelekis A, Kaminski N, Zhang X, Yu J, Jamali H, Ellman JA, Lolis E, Anderson KS, Bennett AM. Sci Signal. 2020 Aug 25; 2020 Aug 25. PMID: 32843541.
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors.Ruiz VG, Czyzyk DJ, Kumar VP, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2020 Aug 15; 2020 May 30. PMID: 32631514.
Unique genomic and neoepitope landscapes across tumors: a study across time, tissues, and space within a single lynch syndrome patient.Phung TN, Lenkiewicz E, Malasi S, Sharma A, Anderson KS, Wilson MA, Pockaj BA, Barrett MT. Sci Rep. 2020 Jul 22; 2020 Jul 22. PMID: 32699259.
Change in 21-gene Recurrence Score result after exposure to neo-adjuvant endocrine therapy in patients with operable breast cancer.Hilal T, Mi L, Ertz-Archambault NM, Almquist DR, Anderson KS, Gray RJ, Pockaj BA, Northfelt DW. Breast J. 2020 Jul; 2019 Dec 26. PMID: 31876083.
Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patient.Duong VN, Zhou L, Martínez-Jiménez MI, He L, Cosme M, Blanco L, Paintsil E, Anderson KS. Sci Rep. 2020 Jun 9; 2020 Jun 9. PMID: 32518272.
Structure-Guided Identification of DNMT3B Inhibitors.Newton AS, Faver JC, Micevic G, Muthusamy V, Kudalkar SN, Bertoletti N, Anderson KS, Bosenberg MW, Jorgensen WL. ACS Med Chem Lett. 2020 May 14; 2020 Feb 7. PMID: 32435413.
Depomedroxyprogesterone acetate therapy for hot flashes in survivors of breast cancer: no unfavorable impact on recurrence and survival.Ertz-Archambault NM, Rogoff LB, Kosiorek HE, Ernst BJ, Anderson KS, Pockaj BA, Gray RJ, Northfelt DW. Support Care Cancer. 2020 May; 2019 Aug 11. PMID: 31402403.
Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors.Czyzyk DJ, Valhondo M, Deiana L, Tirado-Rives J, Jorgensen WL, Anderson KS. Eur J Med Chem. 2019 Dec 1; 2019 Sep 4. PMID: 31536894.
Weakly immunogenic CRISPR therapies.Wilson EA, Anderson KS. Nat Biomed Eng. 2019 Oct. PMID: 31591524.
Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine.Bertoletti N, Chan AH, Schinazi RF, Yin YW, Anderson KS. Protein Sci. 2019 Sep; 2019 Aug 6. PMID: 31301259.
Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase.Sasaki T, Gannam ZTK, Kudalkar SN, Frey KM, Lee WG, Spasov KA, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2019 Aug 15; 2019 Jun 26. PMID: 31281023.
Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer.McDonald BR, Contente-Cuomo T, Sammut SJ, Odenheimer-Bergman A, Ernst B, Perdigones N, Chin SF, Farooq M, Mejia R, Cronin PA, Anderson KS, Kosiorek HE, Northfelt DW, McCullough AE, Patel BK, Weitzel JN, Slavin TP, Caldas C, Pockaj BA, Murtaza M. Sci Transl Med. 2019 Aug 7. PMID: 31391323.
Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase.Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS. FEBS Lett. 2019 Aug; 2019 Jun 18. PMID: 31172516.
The burden of 14 hr-HPV genotypes in women attending routine cervical cancer screening in 20 states of Mexico: a cross-sectional study.Campos-Romero A, Anderson KS, Longatto-Filho A, Luna-Ruiz Esparza MA, Morán-Portela DJ, Castro-Menéndez JA, Moreno-Camacho JL, Calva-Espinosa DY, Acosta-Alfaro MA, Meynard-Mejía FA, Muñoz-Gaitán M, Alcántar-Fernández J. Sci Rep. 2019 Jul 12; 2019 Jul 12. PMID: 31300693.
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.Kudalkar SN, Ullah I, Bertoletti N, Mandl HK, Cisneros JA, Beloor J, Chan AH, Quijano E, Saltzman WM, Jorgensen WL, Kumar P, Anderson KS. Antiviral Res. 2019 Jul; 2019 Apr 26. PMID: 31034849.
Novel allosteric covalent inhibitors of bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa identified by virtual screening.Ruiz V, Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2019 Jun 1; 2019 Mar 20. PMID: 30929953.
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.Cannataro VL, Gaffney SG, Sasaki T, Issaeva N, Grewal NKS, Grandis JR, Yarbrough WG, Burtness B, Anderson KS, Townsend JP. Oncogene. 2019 May; 2019 Jan 15. PMID: 30647454.
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes.Ferdosi SR, Ewaisha R, Moghadam F, Krishna S, Park JG, Ebrahimkhani MR, Kiani S, Anderson KS. Nat Commun. 2019 Apr 23; 2019 Apr 23. PMID: 31015529.
The neoepitope landscape of breast cancer: implications for immunotherapy.Narang P, Chen M, Sharma AA, Anderson KS, Wilson MA. BMC Cancer. 2019 Mar 4; 2019 Mar 4. PMID: 30832597.
HPV: Immunology lessons from an ancient oncotarget.Krishna S, Anderson KS. Oncotarget. 2019 Feb 12; 2019 Feb 12. PMID: 30863487.
The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance through STAT3 Activation and EMT.Ryan MR, Sohl CD, Luo B, Anderson KS. Mol Cancer Res. 2019 Feb; 2018 Sep 26. PMID: 30257990.
Tripled yield in direct-drive laser fusion through statistical modelling.Gopalaswamy V, Betti R, Knauer JP, Luciani N, Patel D, Woo KM, Bose A, Igumenshchev IV, Campbell EM, Anderson KS, Bauer KA, Bonino MJ, Cao D, Christopherson AR, Collins GW, Collins TJB, Davies JR, Delettrez JA, Edgell DH, Epstein R, Forrest CJ, Froula DH, Glebov VY, Goncharov VN, Harding DR, Hu SX, Jacobs-Perkins DW, Janezic RT, Kelly JH, Mannion OM, Maximov A, Marshall FJ, Michel DT, Miller S, Morse SFB, Palastro J, Peebles J, Radha PB, Regan SP, Sampat S, Sangster TC, Sefkow AB, Seka W, Shah RC, Shmyada WT, Shvydky A, Stoeckl C, Solodov AA, Theobald W, Zuegel JD, Johnson MG, Petrasso RD, Li CK, Frenje JA. Nature. 2019 Jan; 2019 Jan 30. PMID: 30700868.
A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women over age 50 with BI-RADS 3, 4, or 5 Assessment.Henderson MC, Silver M, Tran Q, Letsios EE, Mulpuri R, Reese DE, Lourenco AP, LaBaer J, Anderson KS, Alpers J, Costantini C, Rohatgi N, Ali H, Baker K, Northfelt DW, Ghosh K, Grobmyer SR, Polen W, Wolf JK. Clin Cancer Res. 2019 Jan 1; 2018 Sep 5. PMID: 30185421.
Lost in the crowd: identifying targetable MHC class I neoepitopes for cancer immunotherapy.Wilson EA, Anderson KS. Expert Rev Proteomics. 2018 Dec; 2018 Nov 14. PMID: 30408427.
Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8(+) T Cells in Head and Neck Cancer.Krishna S, Ulrich P, Wilson E, Parikh F, Narang P, Yang S, Read AK, Kim-Schulze S, Park JG, Posner M, Wilson Sayres MA, Sikora A, Anderson KS. Cancer Res. 2018 Nov 1; 2018 Aug 28. PMID: 30154146.
Eccrine Sweat as a Biofluid for Profiling Immune Biomarkers.Katchman BA, Zhu M, Blain Christen J, Anderson KS. Proteomics Clin Appl. 2018 Nov; 2018 Jun 28. PMID: 29882373.
DRONE: Direct Tracking of DNA Cytidine Deamination and Other DNA Modifying Activities.Sasaki T, Kudalkar SN, Bertoletti N, Anderson KS. Anal Chem. 2018 Oct 16; 2018 Sep 28. PMID: 30256094.
A compact, low-cost, quantitative and multiplexed fluorescence detection platform for point-of-care applications.Obahiagbon U, Smith JT, Zhu M, Katchman BA, Arafa H, Anderson KS, Blain Christen JM. Biosens Bioelectron. 2018 Oct 15; 2018 Apr 4. PMID: 29894852.
JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer.Chen M, Pockaj B, Andreozzi M, Barrett MT, Krishna S, Eaton S, Niu R, Anderson KS. Clin Breast Cancer. 2018 Oct; 2018 May 26. PMID: 29933930.
Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection.Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2018 Aug 28; 2018 Aug 10. PMID: 30097540.
Tumor-associated autoantibodies as early detection markers for ovarian cancer? A prospective evaluation.Kaaks R, Fortner RT, Hüsing A, Barrdahl M, Hopper M, Johnson T, Tjønneland A, Hansen L, Overvad K, Fournier A, Boutron-Ruault MC, Kvaskoff M, Dossus L, Johansson M, Boeing H, Trichopoulou A, Benetou V, La Vecchia C, Sieri S, Mattiello A, Palli D, Tumino R, Matullo G, Onland-Moret NC, Gram IT, Weiderpass E, Sánchez MJ, Navarro Sanchez C, Duell EJ, Ardanaz E, Larranaga N, Lundin E, Idahl A, Jirström K, Nodin B, Travis RC, Riboli E, Merritt M, Aune D, Terry K, Cramer DW, Anderson KS. Int J Cancer. 2018 Aug 1; 2018 Mar 8. PMID: 29473162.
The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers.Barrett MT, Lenkiewicz E, Malasi S, Basu A, Yearley JH, Annamalai L, McCullough AE, Kosiorek HE, Narang P, Wilson Sayres MA, Chen M, Anderson KS, Pockaj BA. Breast Cancer Res. 2018 Jul 11; 2018 Jul 11. PMID: 29996881.
Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent.Yang M, Wu H, Chu J, Gabriel LA, Kim Y, Anderson KS, Furdui CM, Bierbach U. Chem Commun (Camb). 2018 Jul 11; 2018 Jun 19. PMID: 29915817.
Activity and fidelity of human DNA polymerase α depend on primer structure.Baranovskiy AG, Duong VN, Babayeva ND, Zhang Y, Pavlov YI, Anderson KS, Tahirov TH. J Biol Chem. 2018 May 4; 2018 Mar 19. PMID: 29555682.
Pre-diagnostic dynamic HPV16 IgG seropositivity and risk of oropharyngeal cancer: Methodologic issues.Anderson KS, Mork J, Langseth H, Wallstrom G. Oral Oncol. 2018 May; 2018 Mar 30. PMID: 29606498.
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.Ziegler SJ, Liu C, Landau M, Buzovetsky O, Desimmie BA, Zhao Q, Sasaki T, Burdick RC, Pathak VK, Anderson KS, Xiong Y. PLoS One. 2018; 2018 Mar 29. PMID: 29596531.
An Automated Microfluidic Assay for Photonic Crystal Enhanced Detection and Analysis of an Antiviral Antibody Cancer Biomarker in Serum.Race CM, Kwon LE, Foreman MT, Huang Q, Inan H, Kesiraju S, Le P, Lim SJ, Smith AM, Zangar RC, Demirci U, Anderson KS, Cunningham BT. IEEE Sens J. 2018 Feb 15; 2017 Nov 24. PMID: 29881332.
Modeling the Subclonal Evolution of Cancer Cell Populations.Chowell D, Napier J, Gupta R, Anderson KS, Maley CC, Sayres MAW. Cancer Res. 2018 Feb 1; 2017 Nov 29. PMID: 29187407.
From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2018 Jan 23; 2017 Dec 26. PMID: 29279368.
Stage Dependence, Cell-Origin Independence, and Prognostic Capacity of Serum Glycan Fucosylation, β1-4 Branching, β1-6 Branching, and α2-6 Sialylation in Cancer.Ferdosi S, Rehder DS, Maranian P, Castle EP, Ho TH, Pass HI, Cramer DW, Anderson KS, Fu L, Cole DEC, Le T, Wu X, Borges CR. J Proteome Res. 2018 Jan 5; 2017 Nov 21. PMID: 29129073.
Diagnostic accuracy of serum antibodies to human papillomavirus type 16 early antigens in the detection of human papillomavirus-related oropharyngeal cancer.Dahlstrom KR, Anderson KS, Field MS, Chowell D, Ning J, Li N, Wei Q, Li G, Sturgis EM. Cancer. 2017 Dec 15; 2017 Sep 12. PMID: 28898394.
Discussion of: "The success of sentinel lymph node biopsy after neoadjuvant therapy: A single institution review".Chang JM, Kosiorek HE, Wasif N, Gray RJ, Stucky CH, Northfelt DW, Anderson KS, McCullough AE, Tolgay Ocal I, Pockaj BA. Am J Surg. 2017 Dec; 2017 Sep 30. PMID: 29037421.
The success of sentinel lymph node biopsy after neoadjuvant therapy: A single institution review.Chang JM, Kosiorek HE, Wasif N, Gray RJ, Stucky CH, Northfelt DW, Anderson KS, McCullough AE, Ocal IT, Pockaj BA. Am J Surg. 2017 Dec; 2017 Sep 18. PMID: 28943062.
Development and validation of a novel clinical fluorescence in situ hybridization assay to detect JAK2 and PD-L1 amplification: a fluorescence in situ hybridization assay for JAK2 and PD-L1 amplification.Chen M, Andreozzi M, Pockaj B, Barrett MT, Ocal IT, McCullough AE, Linnaus ME, Chang JM, Yearley JH, Annamalai L, Anderson KS. Mod Pathol. 2017 Nov; 2017 Jul 28. PMID: 28752839.
Pre-diagnostic dynamic HPV16 IgG seropositivity and risk of oropharyngeal cancer.Anderson KS, Wallstrom G, Langseth H, Posner M, Cheng JN, Alam R, Chowell D, Furre IE, Mork J. Oral Oncol. 2017 Oct; 2017 Sep 1. PMID: 28939065.
Classifying the evolutionary and ecological features of neoplasms.Maley CC, Aktipis A, Graham TA, Sottoriva A, Boddy AM, Janiszewska M, Silva AS, Gerlinger M, Yuan Y, Pienta KJ, Anderson KS, Gatenby R, Swanton C, Posada D, Wu CI, Schiffman JD, Hwang ES, Polyak K, Anderson ARA, Brown JS, Greaves M, Shibata D. Nat Rev Cancer. 2017 Oct; 2017 Sep 15. PMID: 28912577.
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.Chan AH, Lee WG, Spasov KA, Cisneros JA, Kudalkar SN, Petrova ZO, Buckingham AB, Anderson KS, Jorgensen WL. Proc Natl Acad Sci U S A. 2017 Sep 5; 2017 Aug 21. PMID: 28827354.