Oligonucleotide Synthesis Pricing
Rates as of 7/1/2024
| Service | Description | Yale Cost per sample* | Non-Yale Cost per sample* |
|---|---|---|---|
| Unpurified DNA | |||
| 25 nanomole scale-96-well PLATE for >47 oligos (DESALTED, =65 bases/un-modified ONLY!) (Yield of final product will be <25 nmoles) | residue charge | $0.22 | $0.28 |
| 25 nanomole scale-TUBES (DESALTED, =65 bases/un-modified ONLY!) (Yield of final product will be <25 nmoles) | residue charge | $0.23 | $0.31 |
| 100 nanomole scale-96-well PLATE for >47 oligos (DESALTED, 1-119 bases with 3' dA, dG, dC or dT) (Yield of final product will be <100 nmoles) | residue charge | $0.27 | $0.35 |
| 100 nanomole scale-TUBES (DESALTED, 1-119 bases with 3' dA, dG, dC or dT) (Yield of final product will be <100 nmoles) | residue charge | $0.30 | $0.37 |
| 40 nanomole scale (>119 bases and/or modified) (Yield of final product will be <40 nmoles) | residue charge | $0.57 | $0.70 |
| 200 nanomole scale (Yield of final product will be <200 nmoles) | residue charge | $0.88 | $1.15 |
| 1.0 Micromole Scale (Yield of final product will be < 1.0 umole) | residue charge | $2.20 | $2.75 |
| RNA/2'-O-Methyl RNA | |||
| 1.0 Micromole Scale (Yield of final product will be <1.0 umole) | residue charge | $17.00 | $21.00 |
| Purified DNA | |||
|
Cartridge Purified DNA-all synthesis scales except 25 nanomole
|
Surcharge per oligo | $17.00 | $25.00 |
| RP-HPLC/All Synthesis Scales (< 100-mers - DNA only) | Surcharge per oligo | $58.00 | $72.00 |
| 40 nanomole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $52.00 | $65.00 |
| 200 nanomole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $90.00 | $110.00 |
| 1.0 umole PAGE purification (surcharge per Oligo) | Surcharge per oligo | $285.00 | $355.00 |
| Purified RNA | |||
| 2' Deprotection/Purification | Surcharge per oligo | $58.00 | $73.00 |
Consulting |
Consulting Charge (per hour) | $30.00 | $51.75 |
| Custom Processing | Pooling, Normalization, Special Packaging (surcharge per oligo) | Request A Quote | - |
| Custom Processing | Custom synthesizer programming (surcharge per oligo) | Request A Quote | - |
*E-mail oligos@yale.edu for for-profit company pricing.