The goal of the Yale DRC is to enhance the quality of research and training in diabetes and related metabolic and endocrine disorders at the University. The Center currently brings together a multidisciplinary group of nearly 100 member scientists, new investigators and research trainees from the Departments of Internal Medicine, Pediatrics, Immunobiology, Biology, Cell Biology, Molecular Biophysics and Biochemistry, Bioengineering, Genetics, Molecular, Cellular and Developmental Biology, Physiology, Pharmacology, Surgery, Orthopedics, Neurosurgery, Neurology, Psychiatry, Obstetrics and Gynecology, Diagnostic Radiology, Psychology, Pathology, Laboratory Medicine, and from the Schools of Public Health and Nursing and the Pierce Laboratory. The cornerstone of the Center is its 5 Research Cores (clinical metabolism core, molecular genetic mouse core, physiology core, cell biology core, and human translation core), which provide funded basic and clinical investigators with the opportunity to more efficiently utilize resources and expand the scope of their research programs.