2022
Dolutegravir hypersensitivity reaction: the need for strengthening pharmacovigilance systems with optimization of antiretroviral therapy in HIV programs in resource-limited settings (case report)
Adeiza M, Kekulah I, Wachekwa I, Ogbuagu O. Dolutegravir hypersensitivity reaction: the need for strengthening pharmacovigilance systems with optimization of antiretroviral therapy in HIV programs in resource-limited settings (case report). PAMJ Clinical Medicine 2022, 8 DOI: 10.11604/pamj-cm.2022.8.47.33930.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAdverse drug reactionsDrug reactionsHIV programsResource-limited settingsAntiretroviral therapyHypersensitivity reactionsAdvanced HIV diseaseLamivudine/tenofovirLamivudine/zidovudineRoutine laboratory monitoringCombination antiretroviral therapyAntiretroviral drug treatmentFirst-line cARTFeatures of anaphylaxisRelevant health educationDrug discontinuityViral suppressionHIV diseaseHIV infectionBlood workOpportunistic infectionsLaboratory monitoringNew symptomsDrug treatmentMedical treatment
2018
Infections in HIV-Infected Patients
Ogbuagu O, Bruce R. Infections in HIV-Infected Patients. 2018, 243-281. DOI: 10.1007/978-3-319-77674-3_13.ChaptersHuman immunodeficiency virusCombination antiretroviral therapyCD4 countCertain infectionsLife-threatening infectious complicationsHigher CD4 countsAntiretroviral therapyImmune reconstitutionInfectious complicationsUntreated patientsImmune defectsClinical presentationImmunodeficiency syndromeCommon infectionsImmunodeficiency virusPatientsNatural historyInfectionChief causeCountCD4ComplicationsSequelaePrognosisPathogenesis
2017
Comparison of Time to Viral Suppression Among Treatment-Naïve HIV-Infected Adults Initiating Combination Antiretroviral Therapy by Antiretroviral Regimen Class
Jacobson K, Ogbuagu O. Comparison of Time to Viral Suppression Among Treatment-Naïve HIV-Infected Adults Initiating Combination Antiretroviral Therapy by Antiretroviral Regimen Class. Open Forum Infectious Diseases 2017, 4: s432-s432. PMCID: PMC5630773, DOI: 10.1093/ofid/ofx163.1090.Peer-Reviewed Original ResearchViral suppressionAntiretroviral therapyART initiationMedian timeART regimensHIV patientsRetrospective single-center chart reviewTreatment-naïve HIV patientsSingle-center chart reviewProtease inhibitorsART regimen typeTreatment-naïve HIVCombination antiretroviral therapyBaseline viral loadTreatment of HIVStudy inclusion criteriaNon-nucleoside reverseRoutine clinical settingLower median timeART regimenINSTI regimensNonstandard regimensRegimen typeVirologic suppressionVirologic failure