2024
Peripheral Arterial Disease prevalence and risk factors in the Eastern Caribbean Health Outcomes Research Network (ECHORN) cohort
Adams O, Galusha D, Martinez-Brockman J, Morris E, Hassan S, Maharaj R, Nazario C, Nunez M, Nunez-Smith M. Peripheral Arterial Disease prevalence and risk factors in the Eastern Caribbean Health Outcomes Research Network (ECHORN) cohort. PLOS ONE 2024, 19: e0306918. PMID: 39186495, PMCID: PMC11346651, DOI: 10.1371/journal.pone.0306918.Peer-Reviewed Original ResearchConceptsEastern Caribbean Health Outcomes Research NetworkAnkle brachial indexPeripheral arterial disease prevalencePeripheral arterial diseasePotential risk factorsSample of community-dwelling peopleRisk factorsCommunity-dwelling peopleAssociation of potential risk factorsFemale sexLower educational attainmentHistory of heart diseaseRisk factors of peripheral arterial diseaseCohort Study participantsAssociated with peripheral arterial diseaseHigh school educationHeart diseaseBody mass indexMultivariate logistic regressionOscillometric deviceAssociation of increasing ageSmoking statusYears of ageStudy participantsHeart disease history
2020
Is hypertension in African-descent populations contributed to by an imbalance in the activities of the ACE2/Ang-(1-7)/Mas and the ACE/Ang II/AT1 axes?
Cohall D, Ojeh N, Ferrario CM, Adams OP, Nunez-Smith M. Is hypertension in African-descent populations contributed to by an imbalance in the activities of the ACE2/Ang-(1-7)/Mas and the ACE/Ang II/AT1 axes? Journal Of The Renin-Angiotensin-Aldosterone System 2020, 21: 1470320320908186. PMID: 32089050, PMCID: PMC7036504, DOI: 10.1177/1470320320908186.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAngiotensin IAngiotensin IIAngiotensin-Converting Enzyme 2Black PeopleHumansHypertensionMiddle AgedPeptide FragmentsPeptidesPeptidyl-Dipeptidase AProto-Oncogene MasProto-Oncogene ProteinsReceptor, Angiotensin, Type 1Receptors, G-Protein-CoupledRenin-Angiotensin SystemYoung AdultConceptsRenin angiotensin aldosterone systemAngiotensin aldosterone systemAldosterone systemClinical blood pressure readingsType 2 diabetes mellitusACE2/AngEnzyme 2 activityChronic renal diseaseBlood pressure readingsVenous blood samplesAfro-Caribbean originAntihypertensive treatmentMineralocorticoid blockersPressor armDiabetes mellitusRenal diseaseReceptor axisAfrican descentUrine collectionEnzyme 2Blood samplesHypertensionPressure readingsAnthropometric dataAfrican descent populations
2019
Phenotypes of Hypertensive Ambulatory Blood Pressure Patterns: Design and Rationale of the ECHORN Hypertension Study.
Spatz ES, Martinez-Brockman JL, Tessier-Sherman B, Mortazavi B, Roy B, Schwartz JI, Nazario CM, Maharaj R, Nunez M, Adams OP, Burg M, Nunez-Smith M. Phenotypes of Hypertensive Ambulatory Blood Pressure Patterns: Design and Rationale of the ECHORN Hypertension Study. Ethnicity & Disease 2019, 29: 535-544. PMID: 31641320, PMCID: PMC6802166, DOI: 10.18865/ed.29.4.535.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure measurementsABPM patternsBP patternAmbulatory blood pressure patternsMore precision-based approachesAmbulatory BP patternsDiagnosis of HTNTreatment of HTNBlood pressure patternWave 2High-risk populationBlood pressure measurementsCommunity-residing adultsPrecision-based approachesAntihypertensive medicationsBlood pressureProspective studyHypertension StudyHypertensive phenotypeCardiovascular diseaseParent studyHTNEcological momentary assessmentSelf-report surveyHigh rate
2018
Non-communicable chronic diseases and timely breast cancer screening among women of the Eastern Caribbean Health Outcomes Research Network (ECHORN) Cohort Study
Wang KH, Thompson TA, Galusha D, Friedman H, Nazario CM, Nunez M, Maharaj RG, Adams OP, Nunez-Smith M, on behalf of the ECHORN Writing Group. Non-communicable chronic diseases and timely breast cancer screening among women of the Eastern Caribbean Health Outcomes Research Network (ECHORN) Cohort Study. Cancer Causes & Control 2018, 29: 315-324. PMID: 29423760, PMCID: PMC6587190, DOI: 10.1007/s10552-018-1005-4.Peer-Reviewed Original ResearchConceptsNon-communicable chronic diseasesTimely breast cancer screeningBreast cancer screeningChronic diseasesCancer screeningBreast cancerEastern Caribbean Health Outcomes Research Network (ECHORN) Cohort StudyUsual sourceReceipt of mammographyChronic disease controlCohort studyEligible womenCancer deathCross-sectional data analysisPreventive screeningCancer preventionSubstantial burdenClinical providersTimely screeningDiabetesTimely mammographyBivariate analysisHypertensionDisease controlDisease