1995
Na+ channel β1 subunit mRNA expression in developing rat central nervous system
Sashihara S, Oh Y, Black J, Waxman S. Na+ channel β1 subunit mRNA expression in developing rat central nervous system. Brain Research 1995, 34: 239-250. PMID: 8750827, DOI: 10.1016/0169-328x(95)00168-r.Peer-Reviewed Original ResearchConceptsGranule cell layerCell layerRat central nervous systemBeta 1Channel beta 1 subunitRexed's lamina IXDentate granule cellsPyramidal cell layerPostnatal day 2Beta 1 expressionSpecific neuronal populationsVentral-dorsal gradientCentral nervous systemSubunit mRNA expressionVoltage-dependent sodium channelsExternal granule cell layerInternal granule cell layerDorsal hornVentral hornLamina IXSpinal cordBeta 1 subunitAdult ratsIntensity of labelingGranule cells
1993
Peripheral nerve abnormalities in multiple sclerosis
Waxman S. Peripheral nerve abnormalities in multiple sclerosis. Muscle & Nerve 1993, 16: 1-5. PMID: 8380899, DOI: 10.1002/mus.880160102.Peer-Reviewed Original Research
1992
Effects of Temperature on Evoked Electrical Activity and Anoxic Injury in CNS White Matter
Stys P, Waxman S, Ransom B. Effects of Temperature on Evoked Electrical Activity and Anoxic Injury in CNS White Matter. Cerebrovascular And Brain Metabolism Reviews 1992, 12: 977-986. PMID: 1400652, DOI: 10.1038/jcbfm.1992.135.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsCarrier ProteinsCentral Nervous SystemCold TemperatureEvoked PotentialsHypoxiaOptic NerveRatsSodium-Calcium ExchangerTemperatureConceptsFunctional recoveryWhite matterAnoxic injuryMin of anoxiaOptic nerveFunctional outcomeTypical CNS white matter tractAnoxic exposureIntracellular Ca2Anoxic/ischemic injuryCNS white matter tractCompound action potential areaGray matterIsolated rat optic nerveGreater functional recoveryEvoked electrical activityAction potential areaCNS white matterRat optic nerveWhite matter tractsFunctional injuryIschemic injuryPathological increaseAnoxic damageCAP peakIonic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger
Stys P, Waxman S, Ransom B. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. Journal Of Neuroscience 1992, 12: 430-439. PMID: 1311030, PMCID: PMC6575619, DOI: 10.1523/jneurosci.12-02-00430.1992.Peer-Reviewed Original ResearchConceptsRat optic nerveCompound action potentialAnoxic injuryOptic nerveWhite matterAction potentialsCentral white matter tractsWhite matter injuryCNS white matterMembrane depolarizationAnoxia/ischemiaWhite matter tractsCNS protectionAnoxic insultMyelinated tractsChannel blockersExchanger blockerIrreversible injuryExtracellular Ca2Mammalian CNSNerveInjuryMore injuriesBlockersFunctional integrity
1991
Reverse Operation of the Na+ ‐Ca2+ Exchanger Mediates Ca 2+ Influx during Anoxia in Mammalian CNS White Mattera
STYS P, WAXMAN S, RANSOM B. Reverse Operation of the Na+ ‐Ca2+ Exchanger Mediates Ca 2+ Influx during Anoxia in Mammalian CNS White Mattera. Annals Of The New York Academy Of Sciences 1991, 639: 328-332. PMID: 1785859, DOI: 10.1111/j.1749-6632.1991.tb17321.x.Peer-Reviewed Original ResearchNon-synaptic mechanisms of Ca2+-mediated injury in CNS white matter
Waxman S, Ransom B, Stys P. Non-synaptic mechanisms of Ca2+-mediated injury in CNS white matter. Trends In Neurosciences 1991, 14: 461-468. PMID: 1722366, DOI: 10.1016/0166-2236(91)90046-w.Peer-Reviewed Original ResearchDifferential sensitivity to hypoxia of the peripheral versus central trajectory of primary afferent axons
Utzschneider D, Kocsis J, Waxman S. Differential sensitivity to hypoxia of the peripheral versus central trajectory of primary afferent axons. Brain Research 1991, 551: 136-141. PMID: 1913145, DOI: 10.1016/0006-8993(91)90924-k.Peer-Reviewed Original ResearchConceptsDorsal columnsDorsal rootsAfferent fibersCentral nervous system componentsPrimary afferent fibersSucrose gap chamberAction potential amplitudePrimary afferent axonsCompound action potentialDorsal spinal rootsNervous system componentsAxonal trunksPeripheral nervesSpinal cordSpinal rootsAfferent axonsCNS portionSchwann cellsAdult ratsPotential amplitudeAxon branchesAction potentialsHypoxiaMembrane potential changesMembrane depolarization
1990
Anoxic injury of mammalian central white matter: Decreased susceptibility in myelin‐deficient optic nerve
Waxman S, Davis P, Black J, Ransom B. Anoxic injury of mammalian central white matter: Decreased susceptibility in myelin‐deficient optic nerve. Annals Of Neurology 1990, 28: 335-340. PMID: 2241117, DOI: 10.1002/ana.410280306.Peer-Reviewed Original ResearchConceptsCompound action potentialOptic nerveCentral white matterMinutes of anoxiaAction potentialsMD ratsWhite matterMammalian central white matterSupramaximal compound action potentialCompound action potential amplitudeAction potential amplitudeNeonatal optic nerveRat optic nerveControl optic nervesDistinct action potentialsWhite matter tractsUnaffected male littermatesAnoxic injuryMale littermatesDays postnatalNervePotential amplitudeOligodendroglial proliferationEffects of anoxiaAdult pattern
1988
The perinodal astrocyte
Black J, Waxman S. The perinodal astrocyte. Glia 1988, 1: 169-183. PMID: 2976037, DOI: 10.1002/glia.440010302.Peer-Reviewed Original Research
1977
The conduction properties of axons in central white matter
Waxman S, Swadlow H. The conduction properties of axons in central white matter. Progress In Neurobiology 1977, 8: 297-324. PMID: 335441, DOI: 10.1016/0301-0082(77)90009-0.Peer-Reviewed Original Research
1972
Regional differentiation of the axon: A review with special reference to the concept of the multiplex neuron
Waxman S. Regional differentiation of the axon: A review with special reference to the concept of the multiplex neuron. Brain Research 1972, 47: 269-288. PMID: 4345196, DOI: 10.1016/0006-8993(72)90639-7.Peer-Reviewed Original ResearchRelative Conduction Velocities of Small Myelinated and Non-myelinated Fibres in the Central Nervous System
WAXMAN S, BENNETT M. Relative Conduction Velocities of Small Myelinated and Non-myelinated Fibres in the Central Nervous System. Nature 1972, 238: 217-219. PMID: 4506206, DOI: 10.1038/newbio238217a0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCatsCentral Nervous SystemLizardsMathematicsMyelin SheathNerve Fibers, MyelinatedNeural ConductionNeuronsOculomotor NerveRabbits