A Computational Account of the Development and Evolution of Psychotic Symptoms.
Powers A, Angelos P, Bond A, Farina E, Fredericks C, Gandhi J, Greenwald M, Hernandez-Busot G, Hosein G, Kelley M, Mourgues C, Palmer W, Rodriguez-Sanchez J, Seabury R, Toribio S, Vin R, Weleff J, Woods S, Benrimoh D. A Computational Account of the Development and Evolution of Psychotic Symptoms. Biological Psychiatry 2024 PMID: 39260466, DOI: 10.1016/j.biopsych.2024.08.026.Peer-Reviewed Original ResearchPsychotic symptomsSymptom formationEmergence of psychotic symptomsConversion to psychosisPrediction error signalsIncoming sensory informationHallucination severityDiminished signal-to-noise ratioComputational accountPsychiatric interventionNeural systemsHallucinationsIncreasing convictionOver-reliancePsychosisSensory informationLongitudinal developmentSymptomsBelief formation